| UniProt: | P52045 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12972 | ||
| Length: | 261 (258) | ||
| Sequences: | 12136 | ||
| Seq/Len: | 47.04 |
| SCPB
Paralog alert: 0.66 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: CAID MENB PAAF PAAG SCPB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 180_H | 190_F | 3.361 | 1.00 | |
| 125_S | 183_E | 3.298 | 1.00 | |
| 128_T | 166_P | 3.15 | 1.00 | |
| 190_F | 193_Q | 3.15 | 1.00 | |
| 123_A | 178_L | 2.886 | 1.00 | |
| 16_V | 192_L | 2.728 | 1.00 | |
| 126_T | 184_V | 2.606 | 1.00 | |
| 101_S | 118_S | 2.598 | 1.00 | |
| 165_S | 197_H | 2.575 | 1.00 | |
| 168_T | 171_R | 2.373 | 1.00 | |
| 135_N | 201_K | 2.36 | 1.00 | |
| 171_R | 174_A | 2.301 | 1.00 | |
| 159_E | 165_S | 2.293 | 1.00 | |
| 248_N | 252_E | 2.173 | 1.00 | |
| 156_I | 175_V | 2.167 | 1.00 | |
| 44_N | 96_P | 2.162 | 1.00 | |
| 25_L | 60_K | 2.146 | 1.00 | |
| 7_N | 20_N | 2.132 | 1.00 | |
| 125_S | 170_Q | 2.098 | 1.00 | |
| 102_M | 191_T | 2.095 | 1.00 | |
| 122_I | 182_V | 2.044 | 1.00 | |
| 186_E | 189_D | 2.011 | 1.00 | |
| 102_M | 188_E | 2.003 | 1.00 | |
| 41_S | 91_M | 1.998 | 1.00 | |
| 25_L | 61_V | 1.928 | 1.00 | |
| 161_I | 209_I | 1.908 | 1.00 | |
| 108_W | 130_S | 1.903 | 1.00 | |
| 54_R | 104_E | 1.897 | 1.00 | |
| 159_E | 179_N | 1.879 | 1.00 | |
| 245_E | 254_R | 1.863 | 1.00 | |
| 51_I | 95_F | 1.85 | 1.00 | |
| 170_Q | 174_A | 1.803 | 1.00 | |
| 15_A | 43_L | 1.797 | 1.00 | |
| 159_E | 180_H | 1.792 | 1.00 | |
| 31_V | 35_D | 1.791 | 1.00 | |
| 125_S | 184_V | 1.742 | 1.00 | |
| 16_V | 54_R | 1.736 | 1.00 | |
| 171_R | 175_V | 1.728 | 1.00 | |
| 165_S | 171_R | 1.726 | 1.00 | |
| 154_F | 158_K | 1.719 | 1.00 | |
| 13_K | 49_R | 1.706 | 1.00 | |
| 241_E | 261_H | 1.694 | 1.00 | |
| 122_I | 194_M | 1.66 | 1.00 | |
| 115_I | 121_I | 1.645 | 1.00 | |
| 158_K | 214_R | 1.631 | 1.00 | |
| 10_T | 15_A | 1.622 | 1.00 | |
| 158_K | 213_L | 1.61 | 1.00 | |
| 119_D | 210_K | 1.604 | 1.00 | |
| 43_L | 51_I | 1.597 | 1.00 | |
| 121_I | 155_H | 1.589 | 1.00 | |
| 15_A | 48_I | 1.589 | 1.00 | |
| 123_A | 129_F | 1.579 | 1.00 | |
| 18_E | 56_P | 1.566 | 1.00 | |
| 158_K | 162_F | 1.561 | 1.00 | |
| 20_N | 56_P | 1.558 | 1.00 | |
| 186_E | 190_F | 1.542 | 1.00 | |
| 37_M | 91_M | 1.536 | 1.00 | |
| 12_N | 196_H | 1.531 | 1.00 | |
| 18_E | 54_R | 1.509 | 1.00 | |
| 241_E | 259_V | 1.501 | 1.00 | |
| 192_L | 196_H | 1.495 | 1.00 | |
| 134_V | 164_A | 1.483 | 1.00 | |
| 124_A | 184_V | 1.479 | 1.00 | |
| 182_V | 190_F | 1.457 | 1.00 | |
| 19_F | 32_F | 1.456 | 1.00 | |
| 173_L | 181_V | 1.456 | 1.00 | |
| 187_L | 191_T | 1.44 | 1.00 | |
| 121_I | 151_D | 1.432 | 1.00 | |
| 92_I | 99_I | 1.415 | 1.00 | |
| 17_I | 39_A | 1.399 | 0.99 | |
| 112_F | 131_M | 1.388 | 0.99 | |
| 104_E | 124_A | 1.381 | 0.99 | |
| 8_V | 15_A | 1.381 | 0.99 | |
| 29_S | 32_F | 1.372 | 0.99 | |
| 50_C | 195_A | 1.347 | 0.99 | |
| 24_K | 69_H | 1.335 | 0.99 | |
| 160_L | 167_I | 1.329 | 0.99 | |
| 40_L | 95_F | 1.321 | 0.99 | |
| 104_E | 126_T | 1.321 | 0.99 | |
| 8_V | 43_L | 1.298 | 0.99 | |
| 195_A | 199_S | 1.288 | 0.99 | |
| 103_V | 107_V | 1.286 | 0.99 | |
| 130_S | 166_P | 1.282 | 0.99 | |
| 52_I | 191_T | 1.28 | 0.99 | |
| 188_E | 191_T | 1.27 | 0.99 | |
| 124_A | 187_L | 1.259 | 0.99 | |
| 188_E | 192_L | 1.252 | 0.99 | |
| 155_H | 179_N | 1.25 | 0.99 | |
| 169_A | 181_V | 1.244 | 0.98 | |
| 153_G | 156_I | 1.242 | 0.98 | |
| 11_I | 196_H | 1.242 | 0.98 | |
| 211_E | 215_V | 1.239 | 0.98 | |
| 16_V | 188_E | 1.227 | 0.98 | |
| 11_I | 192_L | 1.226 | 0.98 | |
| 54_R | 188_E | 1.221 | 0.98 | |
| 93_Q | 147_N | 1.213 | 0.98 | |
| 156_I | 159_E | 1.213 | 0.98 | |
| 106_S | 128_T | 1.201 | 0.98 | |
| 11_I | 16_V | 1.2 | 0.98 | |
| 156_I | 171_R | 1.192 | 0.98 | |
| 30_K | 70_E | 1.187 | 0.98 | |
| 35_D | 39_A | 1.183 | 0.98 | |
| 21_Y | 67_D | 1.177 | 0.98 | |
| 21_Y | 24_K | 1.176 | 0.98 | |
| 220_H | 223_N | 1.172 | 0.98 | |
| 37_M | 41_S | 1.172 | 0.98 | |
| 201_K | 206_I | 1.161 | 0.97 | |
| 69_H | 251_L | 1.156 | 0.97 | |
| 198_I | 206_I | 1.151 | 0.97 | |
| 120_L | 194_M | 1.133 | 0.97 | |
| 103_V | 129_F | 1.128 | 0.97 | |
| 51_I | 97_K | 1.116 | 0.96 | |
| 103_V | 115_I | 1.105 | 0.96 | |
| 44_N | 91_M | 1.099 | 0.96 | |
| 167_I | 175_V | 1.083 | 0.96 | |
| 63_S | 111_A | 1.075 | 0.95 | |
| 19_F | 63_S | 1.07 | 0.95 | |
| 103_V | 121_I | 1.058 | 0.95 | |
| 104_E | 187_L | 1.056 | 0.95 | |
| 225_D | 228_E | 1.055 | 0.95 | |
| 16_V | 52_I | 1.05 | 0.94 | |
| 242_D | 260_G | 1.048 | 0.94 | |
| 148_L | 152_A | 1.047 | 0.94 | |
| 120_L | 179_N | 1.046 | 0.94 | |
| 244_Q | 248_N | 1.037 | 0.94 | |
| 183_E | 186_E | 1.037 | 0.94 | |
| 90_R | 94_K | 1.036 | 0.94 | |
| 170_Q | 173_L | 1.035 | 0.94 | |
| 55_A | 58_G | 1.032 | 0.94 | |
| 42_D | 45_R | 1.025 | 0.93 | |
| 46_P | 97_K | 1.02 | 0.93 | |
| 173_L | 178_L | 1.003 | 0.93 | |
| 208_V | 236_A | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3kqfA | 6 | 0.9885 | 100 | 0.015 | Contact Map | 0.841 |
| 3hinA | 2 | 0.9808 | 100 | 0.017 | Contact Map | 0.695 |
| 4jcsA | 1 | 0.9847 | 100 | 0.018 | Contact Map | 0.639 |
| 4jwvA | 2 | 0.9847 | 100 | 0.019 | Contact Map | 0.678 |
| 2pbpA | 1 | 0.9808 | 100 | 0.02 | Contact Map | 0.742 |
| 4lk5A | 3 | 0.9847 | 100 | 0.021 | Contact Map | 0.713 |
| 3h81A | 3 | 0.9808 | 100 | 0.022 | Contact Map | 0.842 |
| 2fbmA | 3 | 0.9847 | 100 | 0.023 | Contact Map | 0.751 |
| 2ej5A | 2 | 0.9808 | 100 | 0.024 | Contact Map | 0.705 |
| 4fzwC | 2 | 0.9808 | 100 | 0.026 | Contact Map | 0.677 |
Sequence Conservation (Image Generated using WebLogo v3)