| UniProt: | P77181 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13747 | ||
| Length: | 196 (172) | ||
| Sequences: | 1728 | ||
| Seq/Len: | 10.05 |
| PAAY
Paralog alert: 0.39 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: CAIE MAA PAAY THGA WBBJ WCAF YRDA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 55_G | 77_D | 3.38 | 1.00 | |
| 64_M | 72_T | 3.195 | 1.00 | |
| 127_M | 133_I | 2.589 | 1.00 | |
| 92_R | 111_E | 2.58 | 1.00 | |
| 14_P | 33_K | 2.528 | 1.00 | |
| 33_K | 54_D | 2.468 | 1.00 | |
| 94_N | 112_N | 2.425 | 1.00 | |
| 54_D | 76_E | 2.423 | 1.00 | |
| 34_G | 55_G | 2.329 | 1.00 | |
| 116_G | 134_V | 2.273 | 1.00 | |
| 70_Q | 106_G | 2.252 | 1.00 | |
| 75_G | 93_R | 2.242 | 1.00 | |
| 108_V | 126_E | 2.235 | 1.00 | |
| 112_N | 130_N | 2.148 | 1.00 | |
| 9_L | 28_D | 2.121 | 1.00 | |
| 39_P | 166_C | 2.112 | 1.00 | |
| 86_L | 89_C | 2.058 | 1.00 | |
| 77_D | 94_N | 2.04 | 1.00 | |
| 30_I | 51_V | 2.018 | 1.00 | |
| 63_V | 83_S | 1.896 | 1.00 | |
| 93_R | 111_E | 1.867 | 1.00 | |
| 25_L | 29_V | 1.82 | 1.00 | |
| 12_V | 30_I | 1.807 | 1.00 | |
| 35_V | 76_E | 1.79 | 1.00 | |
| 20_H | 39_P | 1.754 | 1.00 | |
| 103_V | 107_A | 1.75 | 1.00 | |
| 55_G | 160_Q | 1.745 | 1.00 | |
| 41_A | 62_C | 1.703 | 1.00 | |
| 111_E | 129_A | 1.699 | 1.00 | |
| 76_E | 93_R | 1.682 | 1.00 | |
| 32_G | 54_D | 1.681 | 1.00 | |
| 110_G | 126_E | 1.652 | 1.00 | |
| 113_S | 131_Y | 1.637 | 1.00 | |
| 142_R | 148_E | 1.633 | 1.00 | |
| 5_Q | 8_G | 1.604 | 1.00 | |
| 16_E | 34_G | 1.584 | 1.00 | |
| 22_T | 40_N | 1.584 | 1.00 | |
| 122_K | 125_A | 1.578 | 1.00 | |
| 130_N | 149_L | 1.55 | 1.00 | |
| 62_C | 84_A | 1.542 | 1.00 | |
| 133_I | 140_A | 1.539 | 1.00 | |
| 25_L | 31_L | 1.525 | 1.00 | |
| 92_R | 108_V | 1.494 | 1.00 | |
| 110_G | 129_A | 1.433 | 1.00 | |
| 13_V | 17_S | 1.423 | 1.00 | |
| 5_Q | 10_T | 1.417 | 1.00 | |
| 7_D | 165_R | 1.411 | 1.00 | |
| 145_S | 148_E | 1.4 | 0.99 | |
| 121_V | 138_A | 1.364 | 0.99 | |
| 113_S | 129_A | 1.312 | 0.99 | |
| 61_N | 83_S | 1.306 | 0.99 | |
| 105_D | 123_A | 1.298 | 0.99 | |
| 115_V | 127_M | 1.294 | 0.99 | |
| 28_D | 49_R | 1.276 | 0.99 | |
| 90_I | 108_V | 1.256 | 0.99 | |
| 110_G | 128_P | 1.25 | 0.99 | |
| 37_V | 43_L | 1.23 | 0.98 | |
| 31_L | 37_V | 1.215 | 0.98 | |
| 16_E | 33_K | 1.21 | 0.98 | |
| 131_Y | 140_A | 1.21 | 0.98 | |
| 131_Y | 143_E | 1.2 | 0.98 | |
| 58_I | 80_I | 1.18 | 0.98 | |
| 115_V | 133_I | 1.17 | 0.97 | |
| 30_I | 49_R | 1.17 | 0.97 | |
| 122_K | 138_A | 1.144 | 0.97 | |
| 102_V | 118_S | 1.133 | 0.97 | |
| 40_N | 61_N | 1.129 | 0.97 | |
| 79_H | 155_G | 1.123 | 0.97 | |
| 95_A | 113_S | 1.115 | 0.96 | |
| 140_A | 143_E | 1.114 | 0.96 | |
| 85_I | 100_N | 1.107 | 0.96 | |
| 112_N | 149_L | 1.105 | 0.96 | |
| 115_V | 138_A | 1.098 | 0.96 | |
| 133_I | 138_A | 1.09 | 0.96 | |
| 67_F | 105_D | 1.083 | 0.96 | |
| 128_P | 140_A | 1.051 | 0.94 | |
| 130_N | 146_E | 1.05 | 0.94 | |
| 128_P | 133_I | 1.043 | 0.94 | |
| 134_V | 141_I | 1.043 | 0.94 | |
| 84_A | 101_A | 1.042 | 0.94 | |
| 14_P | 17_S | 1.039 | 0.94 | |
| 22_T | 39_P | 1.036 | 0.94 | |
| 83_S | 100_N | 1.022 | 0.93 | |
| 95_A | 129_A | 1.021 | 0.93 | |
| 128_P | 131_Y | 1.015 | 0.93 | |
| 80_I | 86_L | 1.008 | 0.93 | |
| 31_L | 35_V | 1.006 | 0.93 | |
| 4_Y | 20_H | 1.006 | 0.93 | |
| 85_I | 99_M | 1.002 | 0.92 | |
| 15_E | 33_K | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1v3wA | 1 | 0.8827 | 100 | 0.512 | Contact Map | 0.806 |
| 1xhdA | 1 | 0.8724 | 100 | 0.522 | Contact Map | 0.801 |
| 3r3rA | 1 | 0.8929 | 100 | 0.522 | Contact Map | 0.844 |
| 3ixcA | 1 | 0.852 | 100 | 0.532 | Contact Map | 0.805 |
| 3r1wA | 3 | 0.8827 | 100 | 0.536 | Contact Map | 0.871 |
| 4mfgA | 4 | 0.8469 | 100 | 0.544 | Contact Map | 0.839 |
| 3c8vA | 4 | 0.9337 | 100 | 0.545 | Contact Map | 0.607 |
| 3tv0A | 2 | 0.8827 | 100 | 0.58 | Contact Map | 0.752 |
| 3kwdA | 1 | 0.8469 | 100 | 0.581 | Contact Map | 0.602 |
| 3hsqA | 3 | 0.9898 | 100 | 0.586 | Contact Map | 0.687 |
Sequence Conservation (Image Generated using WebLogo v3)