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OPENSEQ.org
WBBJ - Putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ
UniProt: P37750 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11984
Length: 196 (187)
Sequences: 397
Seq/Len: 2.12
WBBJ
Paralog alert: 0.18 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CAIE MAA PAAY THGA WBBJ WCAF YRDA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
169_I 175_I 4.471 1.00
136_G 155_N 2.953 1.00
160_G 176_A 2.811 1.00
102_I 133_V 2.745 1.00
141_L 147_V 2.68 1.00
92_R 137_Q 2.596 1.00
137_Q 155_N 2.472 1.00
187_N 194_E 2.465 1.00
91_G 137_Q 2.345 1.00
175_I 182_I 2.295 1.00
82_I 88_V 2.164 1.00
173_T 182_I 1.923 0.99
176_A 183_I 1.889 0.99
151_T 168_S 1.865 0.98
153_I 169_I 1.805 0.98
151_T 167_G 1.788 0.98
73_N 93_D 1.788 0.98
170_P 182_I 1.727 0.97
91_G 136_G 1.678 0.96
170_P 175_I 1.608 0.95
131_S 150_G 1.595 0.95
74_V 94_T 1.582 0.94
145_V 163_S 1.573 0.94
157_V 169_I 1.558 0.94
159_V 175_I 1.515 0.92
106_N 149_P 1.491 0.92
156_G 172_N 1.485 0.91
72_D 92_R 1.481 0.91
94_T 136_G 1.47 0.91
51_N 73_N 1.457 0.90
71_S 92_R 1.456 0.90
139_V 171_E 1.444 0.90
151_T 166_R 1.422 0.89
49_G 72_D 1.422 0.89
138_R 156_G 1.386 0.87
94_T 137_Q 1.384 0.87
60_L 68_I 1.377 0.87
136_G 171_E 1.375 0.87
74_V 137_Q 1.361 0.86
123_P 126_R 1.351 0.85
90_I 96_I 1.35 0.85
153_I 165_V 1.35 0.85
50_E 72_D 1.348 0.85
168_S 175_I 1.34 0.85
99_K 144_N 1.332 0.84
107_H 140_W 1.321 0.83
157_V 173_T 1.318 0.83
159_V 169_I 1.31 0.83
163_S 178_V 1.298 0.82
86_E 104_D 1.284 0.81
79_Y 99_K 1.276 0.80
156_G 186_Y 1.274 0.80
70_F 90_I 1.259 0.79
68_I 84_S 1.257 0.79
153_I 175_I 1.225 0.77
70_F 74_V 1.219 0.76
74_V 91_G 1.215 0.76
104_D 149_P 1.215 0.76
138_R 172_N 1.201 0.75
154_G 171_E 1.193 0.74
190_T 194_E 1.183 0.73
153_I 159_V 1.17 0.72
133_V 149_P 1.169 0.72
77_N 97_A 1.167 0.71
186_Y 193_W 1.164 0.71
134_V 152_I 1.151 0.70
140_W 158_V 1.151 0.70
95_L 140_W 1.148 0.70
77_N 98_S 1.139 0.69
106_N 138_R 1.133 0.68
87_S 134_V 1.122 0.67
96_I 133_V 1.119 0.67
135_I 163_S 1.117 0.67
68_I 124_D 1.109 0.66
178_V 181_K 1.108 0.66
173_T 185_K 1.096 0.65
10_G 13_G 1.074 0.62
154_G 170_P 1.072 0.62
192_L 195_K 1.061 0.61
151_T 175_I 1.06 0.61
48_F 52_F 1.055 0.60
80_V 100_V 1.054 0.60
102_I 135_I 1.048 0.59
89_T 136_G 1.046 0.59
155_N 171_E 1.04 0.59
102_I 159_V 1.036 0.58
91_G 139_V 1.029 0.57
85_I 105_H 1.027 0.57
157_V 171_E 1.022 0.57
157_V 175_I 1.011 0.55
81_H 143_E 1.009 0.55
146_T 162_N 1.008 0.55
29_R 34_I 1.005 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3vbiA30.96941000.463Contact Map0.764
1krrA30.93371000.464Contact Map0.755
3srtA20.88781000.465Contact Map0.754
3fttA10.93881000.471Contact Map0.717
3nz2A120.92861000.473Contact Map0.802
2p2oA60.88781000.476Contact Map0.753
3hjjA30.89291000.48Contact Map0.753
1ocxA30.87241000.509Contact Map0.762
2wlgA30.9491000.513Contact Map0.702
3jqyB30.928699.90.541Contact Map0.755
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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