| UniProt: | P07464 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10524 | ||
| Length: | 203 (188) | ||
| Sequences: | 1548 | ||
| Seq/Len: | 8.23 |
| THGA
Paralog alert: 0.45 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: CAIE MAA PAAY THGA WBBJ WCAF YRDA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 90_I | 96_V | 5.071 | 1.00 | |
| 110_L | 132_I | 4.656 | 1.00 | |
| 155_N | 171_N | 3.437 | 1.00 | |
| 168_I | 174_A | 2.885 | 1.00 | |
| 57_T | 77_H | 2.814 | 1.00 | |
| 135_G | 154_D | 2.803 | 1.00 | |
| 111_S | 142_S | 2.67 | 1.00 | |
| 159_G | 175_A | 2.656 | 1.00 | |
| 81_N | 101_N | 2.592 | 1.00 | |
| 140_I | 146_I | 2.546 | 1.00 | |
| 87_N | 107_N | 2.452 | 1.00 | |
| 147_N | 160_A | 2.437 | 1.00 | |
| 136_N | 154_D | 2.349 | 1.00 | |
| 5_M | 8_R | 2.306 | 1.00 | |
| 156_S | 170_P | 2.306 | 1.00 | |
| 100_D | 136_N | 2.148 | 1.00 | |
| 154_D | 170_P | 2.137 | 1.00 | |
| 77_H | 97_T | 2.112 | 1.00 | |
| 110_L | 134_I | 2.104 | 1.00 | |
| 25_K | 74_S | 2.098 | 1.00 | |
| 101_N | 137_N | 1.962 | 1.00 | |
| 137_N | 155_N | 1.96 | 1.00 | |
| 43_E | 46_K | 1.952 | 1.00 | |
| 80_R | 100_D | 1.946 | 1.00 | |
| 29_G | 54_M | 1.837 | 1.00 | |
| 175_A | 182_I | 1.798 | 1.00 | |
| 34_Y | 41_P | 1.739 | 1.00 | |
| 78_I | 82_F | 1.727 | 1.00 | |
| 156_S | 172_V | 1.724 | 1.00 | |
| 158_I | 168_I | 1.711 | 1.00 | |
| 162_S | 179_C | 1.709 | 1.00 | |
| 94_Y | 129_S | 1.706 | 1.00 | |
| 59_G | 80_R | 1.691 | 1.00 | |
| 104_I | 110_L | 1.691 | 1.00 | |
| 117_V | 157_V | 1.683 | 1.00 | |
| 97_T | 133_T | 1.65 | 1.00 | |
| 93_D | 129_S | 1.648 | 1.00 | |
| 34_Y | 38_H | 1.64 | 1.00 | |
| 102_V | 136_N | 1.635 | 1.00 | |
| 117_V | 173_V | 1.579 | 1.00 | |
| 6_T | 25_K | 1.563 | 1.00 | |
| 4_P | 7_E | 1.558 | 1.00 | |
| 140_I | 144_V | 1.551 | 1.00 | |
| 61_N | 81_N | 1.546 | 1.00 | |
| 110_L | 146_I | 1.484 | 1.00 | |
| 35_E | 53_E | 1.476 | 0.99 | |
| 133_T | 151_T | 1.444 | 0.99 | |
| 174_A | 179_C | 1.426 | 0.99 | |
| 46_K | 49_S | 1.414 | 0.99 | |
| 28_R | 32_L | 1.407 | 0.99 | |
| 36_F | 51_I | 1.395 | 0.99 | |
| 123_K | 137_N | 1.379 | 0.99 | |
| 109_T | 143_H | 1.363 | 0.99 | |
| 156_S | 168_I | 1.334 | 0.99 | |
| 158_I | 174_A | 1.333 | 0.99 | |
| 135_G | 156_S | 1.32 | 0.99 | |
| 89_T | 107_N | 1.313 | 0.98 | |
| 98_I | 104_I | 1.311 | 0.98 | |
| 68_V | 76_I | 1.299 | 0.98 | |
| 102_V | 154_D | 1.278 | 0.98 | |
| 29_G | 33_M | 1.272 | 0.98 | |
| 48_E | 52_K | 1.263 | 0.98 | |
| 70_F | 76_I | 1.254 | 0.98 | |
| 31_T | 42_S | 1.244 | 0.98 | |
| 6_T | 74_S | 1.225 | 0.97 | |
| 82_F | 136_N | 1.225 | 0.97 | |
| 58_V | 62_A | 1.203 | 0.97 | |
| 82_F | 100_D | 1.201 | 0.97 | |
| 172_V | 184_E | 1.168 | 0.96 | |
| 84_A | 90_I | 1.164 | 0.96 | |
| 82_F | 102_V | 1.137 | 0.95 | |
| 109_T | 142_S | 1.135 | 0.95 | |
| 77_H | 95_T | 1.132 | 0.95 | |
| 98_I | 110_L | 1.103 | 0.94 | |
| 32_L | 53_E | 1.101 | 0.94 | |
| 61_N | 80_R | 1.095 | 0.94 | |
| 32_L | 54_M | 1.08 | 0.93 | |
| 84_A | 104_I | 1.075 | 0.93 | |
| 6_T | 10_R | 1.061 | 0.93 | |
| 98_I | 134_I | 1.048 | 0.92 | |
| 114_G | 130_F | 1.044 | 0.92 | |
| 108_V | 144_V | 1.044 | 0.92 | |
| 172_V | 181_V | 1.041 | 0.92 | |
| 159_G | 162_S | 1.035 | 0.91 | |
| 79_G | 100_D | 1.029 | 0.91 | |
| 152_I | 174_A | 1.029 | 0.91 | |
| 35_E | 40_H | 1.01 | 0.90 | |
| 138_V | 170_P | 1.008 | 0.90 | |
| 169_P | 174_A | 1.003 | 0.90 | |
| 56_A | 77_H | 1 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1krrA | 3 | 1 | 100 | 0.282 | Contact Map | 0.799 |
| 3srtA | 2 | 0.9212 | 100 | 0.295 | Contact Map | 0.808 |
| 3fttA | 1 | 0.9754 | 100 | 0.295 | Contact Map | 0.739 |
| 2p2oA | 6 | 0.9113 | 100 | 0.305 | Contact Map | 0.865 |
| 3hjjA | 3 | 0.9212 | 100 | 0.311 | Contact Map | 0.848 |
| 3nz2A | 12 | 0.9458 | 100 | 0.315 | Contact Map | 0.902 |
| 1ocxA | 3 | 0.8966 | 100 | 0.333 | Contact Map | 0.837 |
| 3q1xA | 1 | 0.9212 | 100 | 0.623 | Contact Map | 0.472 |
| 3vbiA | 3 | 0.8768 | 100 | 0.629 | Contact Map | 0.763 |
| 3tk8A | 3 | 0.9507 | 100 | 0.63 | Contact Map | 0.539 |
Sequence Conservation (Image Generated using WebLogo v3)