| UniProt: | P76584 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13463 | ||
| Length: | 290 (285) | ||
| Sequences: | 3204 | ||
| Seq/Len: | 11.24 |
| YPHB
Paralog alert: 0.62 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: GALM YEAD YIHR YPHB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 60_N | 73_P | 3.706 | 1.00 | |
| 81_Y | 110_G | 3.431 | 1.00 | |
| 212_I | 250_F | 3.257 | 1.00 | |
| 61_R | 68_E | 2.855 | 1.00 | |
| 94_V | 104_V | 2.582 | 1.00 | |
| 13_L | 25_F | 2.562 | 1.00 | |
| 140_T | 274_A | 2.547 | 1.00 | |
| 260_D | 264_R | 2.504 | 1.00 | |
| 167_W | 202_G | 2.421 | 1.00 | |
| 113_H | 138_A | 2.385 | 1.00 | |
| 7_S | 12_K | 2.363 | 1.00 | |
| 13_L | 22_I | 2.313 | 1.00 | |
| 234_I | 250_F | 2.295 | 1.00 | |
| 106_E | 115_R | 2.283 | 1.00 | |
| 24_G | 31_P | 2.276 | 1.00 | |
| 102_C | 119_A | 2.268 | 1.00 | |
| 20_G | 103_L | 2.265 | 1.00 | |
| 222_I | 286_R | 2.247 | 1.00 | |
| 214_Q | 219_Y | 2.246 | 1.00 | |
| 13_L | 127_L | 2.165 | 1.00 | |
| 30_T | 219_Y | 2.15 | 1.00 | |
| 130_T | 282_E | 2.074 | 1.00 | |
| 72_Q | 86_G | 2.028 | 1.00 | |
| 130_T | 280_T | 2.024 | 1.00 | |
| 132_S | 278_S | 2.022 | 1.00 | |
| 5_T | 14_D | 2.006 | 1.00 | |
| 164_S | 207_N | 2.005 | 1.00 | |
| 4_Y | 101_L | 1.983 | 1.00 | |
| 182_L | 189_N | 1.982 | 1.00 | |
| 89_G | 105_Y | 1.976 | 1.00 | |
| 106_E | 113_H | 1.976 | 1.00 | |
| 168_L | 178_F | 1.962 | 1.00 | |
| 192_A | 197_Q | 1.901 | 1.00 | |
| 128_T | 282_E | 1.867 | 1.00 | |
| 16_S | 23_E | 1.86 | 1.00 | |
| 100_S | 121_H | 1.845 | 1.00 | |
| 114_Y | 143_F | 1.842 | 1.00 | |
| 134_T | 278_S | 1.825 | 1.00 | |
| 117_S | 132_S | 1.796 | 1.00 | |
| 15_V | 103_L | 1.793 | 1.00 | |
| 12_K | 26_W | 1.787 | 1.00 | |
| 121_H | 130_T | 1.749 | 1.00 | |
| 104_V | 117_S | 1.723 | 1.00 | |
| 274_A | 277_E | 1.719 | 1.00 | |
| 17_D | 90_E | 1.716 | 1.00 | |
| 102_C | 117_S | 1.708 | 1.00 | |
| 126_T | 284_S | 1.7 | 1.00 | |
| 104_V | 115_R | 1.688 | 1.00 | |
| 6_L | 122_L | 1.688 | 1.00 | |
| 61_R | 70_Q | 1.688 | 1.00 | |
| 49_P | 118_Q | 1.677 | 1.00 | |
| 224_E | 286_R | 1.674 | 1.00 | |
| 115_R | 134_T | 1.673 | 1.00 | |
| 132_S | 280_T | 1.638 | 1.00 | |
| 60_N | 70_Q | 1.619 | 1.00 | |
| 53_F | 262_H | 1.618 | 1.00 | |
| 159_I | 188_F | 1.616 | 1.00 | |
| 55_N | 233_F | 1.607 | 1.00 | |
| 3_I | 16_S | 1.602 | 1.00 | |
| 128_T | 284_S | 1.597 | 1.00 | |
| 119_A | 132_S | 1.596 | 1.00 | |
| 64_W | 272_A | 1.592 | 1.00 | |
| 126_T | 286_R | 1.59 | 1.00 | |
| 63_V | 68_E | 1.587 | 1.00 | |
| 50_L | 146_G | 1.583 | 1.00 | |
| 123_T | 126_T | 1.581 | 1.00 | |
| 20_G | 49_P | 1.565 | 1.00 | |
| 211_R | 220_A | 1.564 | 1.00 | |
| 142_P | 272_A | 1.562 | 1.00 | |
| 211_R | 222_I | 1.561 | 1.00 | |
| 4_Y | 93_C | 1.54 | 1.00 | |
| 192_A | 196_R | 1.501 | 1.00 | |
| 254_P | 283_M | 1.498 | 1.00 | |
| 194_L | 250_F | 1.494 | 1.00 | |
| 65_Q | 140_T | 1.492 | 1.00 | |
| 107_H | 113_H | 1.488 | 1.00 | |
| 140_T | 275_P | 1.479 | 1.00 | |
| 94_V | 102_C | 1.459 | 1.00 | |
| 188_F | 192_A | 1.45 | 1.00 | |
| 224_E | 284_S | 1.444 | 1.00 | |
| 148_H | 253_E | 1.441 | 1.00 | |
| 79_A | 172_Q | 1.44 | 1.00 | |
| 70_Q | 73_P | 1.429 | 1.00 | |
| 58_S | 260_D | 1.422 | 1.00 | |
| 202_G | 233_F | 1.416 | 1.00 | |
| 193_P | 196_R | 1.411 | 1.00 | |
| 97_S | 100_S | 1.37 | 0.99 | |
| 158_R | 213_E | 1.364 | 0.99 | |
| 158_R | 191_P | 1.354 | 0.99 | |
| 49_P | 147_W | 1.351 | 0.99 | |
| 214_Q | 217_E | 1.333 | 0.99 | |
| 5_T | 12_K | 1.317 | 0.99 | |
| 16_S | 21_V | 1.303 | 0.99 | |
| 204_A | 258_A | 1.302 | 0.99 | |
| 158_R | 215_P | 1.284 | 0.99 | |
| 123_T | 128_T | 1.276 | 0.99 | |
| 260_D | 263_H | 1.273 | 0.99 | |
| 33_L | 149_P | 1.272 | 0.99 | |
| 227_P | 281_S | 1.27 | 0.99 | |
| 161_A | 234_I | 1.267 | 0.99 | |
| 118_Q | 129_V | 1.263 | 0.99 | |
| 92_Q | 104_V | 1.263 | 0.99 | |
| 160_Q | 211_R | 1.262 | 0.99 | |
| 121_H | 128_T | 1.232 | 0.98 | |
| 237_S | 240_A | 1.229 | 0.98 | |
| 152_P | 214_Q | 1.226 | 0.98 | |
| 237_S | 249_F | 1.226 | 0.98 | |
| 65_Q | 139_E | 1.225 | 0.98 | |
| 213_E | 220_A | 1.215 | 0.98 | |
| 65_Q | 274_A | 1.211 | 0.98 | |
| 133_V | 143_F | 1.198 | 0.98 | |
| 169_E | 173_W | 1.186 | 0.98 | |
| 143_F | 273_L | 1.182 | 0.98 | |
| 144_G | 257_H | 1.155 | 0.97 | |
| 232_Y | 252_L | 1.147 | 0.97 | |
| 166_Y | 179_C | 1.144 | 0.97 | |
| 114_Y | 141_L | 1.143 | 0.97 | |
| 18_Q | 90_E | 1.136 | 0.97 | |
| 168_L | 179_C | 1.134 | 0.97 | |
| 143_F | 279_T | 1.134 | 0.97 | |
| 59_G | 80_H | 1.122 | 0.97 | |
| 94_V | 117_S | 1.111 | 0.96 | |
| 83_H | 253_E | 1.11 | 0.96 | |
| 181_Q | 184_Q | 1.098 | 0.96 | |
| 14_D | 24_G | 1.086 | 0.96 | |
| 73_P | 79_A | 1.086 | 0.96 | |
| 22_I | 33_L | 1.085 | 0.96 | |
| 83_H | 148_H | 1.085 | 0.96 | |
| 89_G | 108_R | 1.085 | 0.96 | |
| 226_T | 281_S | 1.077 | 0.95 | |
| 3_I | 14_D | 1.069 | 0.95 | |
| 22_I | 127_L | 1.065 | 0.95 | |
| 136_Q | 141_L | 1.057 | 0.95 | |
| 91_W | 116_V | 1.05 | 0.94 | |
| 59_G | 73_P | 1.048 | 0.94 | |
| 3_I | 23_E | 1.048 | 0.94 | |
| 159_I | 250_F | 1.047 | 0.94 | |
| 273_L | 277_E | 1.039 | 0.94 | |
| 11_L | 25_F | 1.036 | 0.94 | |
| 113_H | 137_G | 1.03 | 0.94 | |
| 212_I | 252_L | 1.029 | 0.94 | |
| 45_A | 87_W | 1.027 | 0.94 | |
| 67_R | 139_E | 1.021 | 0.93 | |
| 11_L | 122_L | 1.017 | 0.93 | |
| 109_S | 139_E | 1.011 | 0.93 | |
| 34_R | 249_F | 1.009 | 0.93 | |
| 146_G | 255_M | 1.008 | 0.93 | |
| 160_Q | 191_P | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1z45A | 1 | 0.9724 | 100 | 0.169 | Contact Map | 0.754 |
| 3nreA | 4 | 0.9931 | 100 | 0.169 | Contact Map | 0.728 |
| 1ygaA | 2 | 0.9759 | 100 | 0.182 | Contact Map | 0.769 |
| 1lurA | 2 | 0.9724 | 100 | 0.186 | Contact Map | 0.846 |
| 1nsxA | 2 | 0.9621 | 100 | 0.201 | Contact Map | 0.835 |
| 1snzA | 2 | 0.969 | 100 | 0.208 | Contact Map | 0.867 |
| 3mwxA | 2 | 0.9724 | 100 | 0.221 | Contact Map | 0.806 |
| 3os7A | 4 | 0.9759 | 100 | 0.223 | Contact Map | 0.72 |
| 3imhA | 2 | 0.9552 | 100 | 0.223 | Contact Map | 0.816 |
| 3q1nA | 1 | 0.9069 | 100 | 0.265 | Contact Map | 0.685 |
Sequence Conservation (Image Generated using WebLogo v3)