| UniProt: | P39173 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12679 | ||
| Length: | 294 (274) | ||
| Sequences: | 1625 | ||
| Seq/Len: | 5.93 |
| YEAD
Paralog alert: 0.42 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: GALM YEAD YIHR YPHB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 106_K | 120_E | 3.396 | 1.00 | |
| 123_Q | 134_D | 3.335 | 1.00 | |
| 49_S | 57_E | 3.026 | 1.00 | |
| 123_Q | 128_K | 2.731 | 1.00 | |
| 31_V | 143_V | 2.558 | 1.00 | |
| 118_T | 140_H | 2.547 | 1.00 | |
| 98_A | 121_L | 2.349 | 1.00 | |
| 38_A | 50_W | 2.274 | 1.00 | |
| 29_I | 117_L | 2.274 | 1.00 | |
| 128_K | 134_D | 2.254 | 1.00 | |
| 41_A | 48_L | 2.201 | 1.00 | |
| 42_L | 102_P | 2.142 | 1.00 | |
| 37_K | 51_K | 2.138 | 1.00 | |
| 32_D | 53_A | 2.054 | 1.00 | |
| 167_F | 220_I | 2.041 | 1.00 | |
| 160_T | 271_A | 2.015 | 1.00 | |
| 278_T | 281_K | 2.011 | 1.00 | |
| 134_D | 153_S | 2.002 | 1.00 | |
| 30_V | 39_S | 1.987 | 1.00 | |
| 140_H | 152_E | 1.954 | 1.00 | |
| 79_V | 139_A | 1.904 | 1.00 | |
| 45_A | 119_F | 1.889 | 1.00 | |
| 120_E | 138_L | 1.88 | 1.00 | |
| 40_F | 117_L | 1.875 | 1.00 | |
| 38_A | 47_L | 1.873 | 1.00 | |
| 32_D | 37_K | 1.868 | 1.00 | |
| 142_R | 150_D | 1.858 | 1.00 | |
| 122_T | 136_T | 1.834 | 1.00 | |
| 36_V | 50_W | 1.813 | 1.00 | |
| 120_E | 136_T | 1.81 | 1.00 | |
| 116_A | 142_R | 1.81 | 1.00 | |
| 232_G | 288_S | 1.795 | 1.00 | |
| 152_E | 284_H | 1.734 | 1.00 | |
| 150_D | 284_H | 1.677 | 1.00 | |
| 98_A | 137_L | 1.644 | 1.00 | |
| 80_C | 162_A | 1.626 | 1.00 | |
| 164_H | 267_E | 1.623 | 1.00 | |
| 116_A | 140_H | 1.604 | 0.99 | |
| 228_I | 292_A | 1.596 | 0.99 | |
| 124_S | 127_T | 1.594 | 0.99 | |
| 156_E | 276_K | 1.576 | 0.99 | |
| 255_M | 263_F | 1.572 | 0.99 | |
| 109_H | 115_V | 1.572 | 0.99 | |
| 162_A | 269_A | 1.57 | 0.99 | |
| 159_T | 283_A | 1.541 | 0.99 | |
| 109_H | 116_A | 1.537 | 0.99 | |
| 232_G | 290_R | 1.533 | 0.99 | |
| 123_Q | 135_F | 1.53 | 0.99 | |
| 78_P | 242_W | 1.519 | 0.99 | |
| 238_N | 273_E | 1.519 | 0.99 | |
| 135_F | 157_F | 1.506 | 0.99 | |
| 277_V | 283_A | 1.486 | 0.99 | |
| 50_W | 291_V | 1.478 | 0.99 | |
| 142_R | 148_E | 1.476 | 0.99 | |
| 104_T | 120_E | 1.464 | 0.99 | |
| 30_V | 37_K | 1.451 | 0.99 | |
| 84_F | 240_V | 1.444 | 0.99 | |
| 123_Q | 127_T | 1.439 | 0.99 | |
| 219_V | 230_A | 1.437 | 0.99 | |
| 45_A | 139_A | 1.426 | 0.98 | |
| 139_A | 149_I | 1.42 | 0.98 | |
| 33_H | 115_V | 1.419 | 0.98 | |
| 101_L | 124_S | 1.415 | 0.98 | |
| 131_W | 157_F | 1.412 | 0.98 | |
| 138_L | 152_E | 1.406 | 0.98 | |
| 156_E | 278_T | 1.402 | 0.98 | |
| 118_T | 138_L | 1.39 | 0.98 | |
| 127_T | 135_F | 1.39 | 0.98 | |
| 256_P | 259_G | 1.388 | 0.98 | |
| 206_R | 248_L | 1.382 | 0.98 | |
| 86_P | 94_A | 1.378 | 0.98 | |
| 239_V | 266_V | 1.374 | 0.98 | |
| 167_F | 229_I | 1.373 | 0.98 | |
| 57_E | 61_L | 1.354 | 0.98 | |
| 250_I | 257_D | 1.322 | 0.97 | |
| 126_E | 129_K | 1.321 | 0.97 | |
| 150_D | 286_A | 1.317 | 0.97 | |
| 94_A | 99_R | 1.313 | 0.97 | |
| 85_G | 94_A | 1.311 | 0.97 | |
| 277_V | 280_E | 1.306 | 0.97 | |
| 159_T | 277_V | 1.304 | 0.97 | |
| 81_W | 137_L | 1.301 | 0.97 | |
| 95_H | 164_H | 1.3 | 0.97 | |
| 29_I | 42_L | 1.292 | 0.97 | |
| 104_T | 122_T | 1.269 | 0.96 | |
| 277_V | 282_P | 1.267 | 0.96 | |
| 106_K | 138_L | 1.251 | 0.96 | |
| 97_F | 100_N | 1.241 | 0.95 | |
| 230_A | 290_R | 1.238 | 0.95 | |
| 47_L | 77_V | 1.225 | 0.95 | |
| 78_P | 265_C | 1.224 | 0.95 | |
| 280_E | 283_A | 1.217 | 0.95 | |
| 28_L | 39_S | 1.21 | 0.95 | |
| 255_M | 259_G | 1.208 | 0.94 | |
| 275_Q | 283_A | 1.207 | 0.94 | |
| 95_H | 267_E | 1.2 | 0.94 | |
| 146_T | 290_R | 1.195 | 0.94 | |
| 43_Q | 102_P | 1.173 | 0.93 | |
| 153_S | 157_F | 1.173 | 0.93 | |
| 217_C | 230_A | 1.171 | 0.93 | |
| 51_K | 57_E | 1.16 | 0.93 | |
| 69_N | 100_N | 1.145 | 0.92 | |
| 78_P | 81_W | 1.143 | 0.92 | |
| 29_I | 105_L | 1.137 | 0.92 | |
| 170_G | 225_L | 1.129 | 0.91 | |
| 50_W | 59_L | 1.127 | 0.91 | |
| 236_H | 270_Y | 1.126 | 0.91 | |
| 148_E | 288_S | 1.09 | 0.89 | |
| 270_Y | 275_Q | 1.089 | 0.89 | |
| 49_S | 61_L | 1.089 | 0.89 | |
| 83_W | 92_L | 1.08 | 0.89 | |
| 105_L | 119_F | 1.064 | 0.88 | |
| 22_K | 25_E | 1.058 | 0.87 | |
| 84_F | 269_A | 1.056 | 0.87 | |
| 31_V | 38_A | 1.04 | 0.86 | |
| 220_I | 266_V | 1.036 | 0.86 | |
| 62_S | 70_G | 1.03 | 0.86 | |
| 277_V | 281_K | 1.025 | 0.85 | |
| 85_G | 99_R | 1.021 | 0.85 | |
| 74_R | 166_Y | 1.018 | 0.85 | |
| 217_C | 232_G | 1.016 | 0.84 | |
| 99_R | 242_W | 1.015 | 0.84 | |
| 80_C | 269_A | 1.011 | 0.84 | |
| 208_D | 240_V | 1.008 | 0.84 | |
| 244_P | 263_F | 1.005 | 0.84 | |
| 97_F | 135_F | 1.004 | 0.83 | |
| 145_K | 290_R | 1.004 | 0.83 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2htaA | 2 | 0.9864 | 100 | 0.232 | Contact Map | 0.685 |
| 2cirA | 1 | 0.9218 | 100 | 0.264 | Contact Map | 0.757 |
| 1jovA | 1 | 0.9082 | 100 | 0.312 | Contact Map | 0.689 |
| 3k25A | 2 | 0.8878 | 100 | 0.365 | Contact Map | 0.785 |
| 3os7A | 4 | 0.9184 | 100 | 0.395 | Contact Map | 0.709 |
| 3mwxA | 2 | 0.9082 | 100 | 0.398 | Contact Map | 0.729 |
| 3q1nA | 1 | 0.8299 | 100 | 0.399 | Contact Map | 0.781 |
| 3dcdA | 2 | 0.8367 | 100 | 0.411 | Contact Map | 0.871 |
| 3nreA | 4 | 0.8333 | 100 | 0.425 | Contact Map | 0.656 |
| 1snzA | 2 | 0.9388 | 100 | 0.432 | Contact Map | 0.688 |
Sequence Conservation (Image Generated using WebLogo v3)