| UniProt: | P69210 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13926 | ||
| Length: | 109 (102) | ||
| Sequences: | 2057 | ||
| Seq/Len: | 20.17 |
| MDTI
Paralog alert: 0.68 [within 20: 0.29] - ratio of genomes with paralogs Cluster includes: EMRE MDTI MDTJ SUGE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 95_G | 105_M | 2.642 | 1.00 | |
| 18_L | 47_A | 2.32 | 1.00 | |
| 81_W | 88_L | 2.163 | 1.00 | |
| 54_Q | 57_K | 2.146 | 1.00 | |
| 16_I | 71_F | 2.133 | 1.00 | |
| 59_I | 64_A | 1.867 | 1.00 | |
| 79_A | 83_L | 1.858 | 1.00 | |
| 25_F | 40_L | 1.791 | 1.00 | |
| 36_I | 40_L | 1.749 | 1.00 | |
| 77_L | 96_L | 1.72 | 1.00 | |
| 22_A | 44_A | 1.679 | 1.00 | |
| 24_V | 79_A | 1.664 | 1.00 | |
| 21_V | 44_A | 1.656 | 1.00 | |
| 29_S | 32_F | 1.627 | 1.00 | |
| 56_V | 61_L | 1.607 | 1.00 | |
| 45_V | 49_F | 1.586 | 1.00 | |
| 98_L | 101_A | 1.55 | 1.00 | |
| 11_W | 51_A | 1.548 | 1.00 | |
| 35_K | 38_G | 1.51 | 1.00 | |
| 93_W | 97_V | 1.5 | 1.00 | |
| 90_R | 94_I | 1.478 | 1.00 | |
| 89_N | 92_G | 1.47 | 1.00 | |
| 20_I | 75_A | 1.465 | 1.00 | |
| 97_V | 101_A | 1.441 | 1.00 | |
| 90_R | 93_W | 1.424 | 1.00 | |
| 21_V | 40_L | 1.377 | 0.99 | |
| 56_V | 64_A | 1.361 | 0.99 | |
| 11_W | 54_Q | 1.36 | 0.99 | |
| 86_Q | 92_G | 1.36 | 0.99 | |
| 98_L | 102_G | 1.343 | 0.99 | |
| 95_G | 102_G | 1.328 | 0.99 | |
| 32_F | 38_G | 1.27 | 0.99 | |
| 22_A | 45_V | 1.256 | 0.99 | |
| 26_L | 41_S | 1.238 | 0.98 | |
| 36_I | 39_L | 1.231 | 0.98 | |
| 99_L | 102_G | 1.224 | 0.98 | |
| 61_L | 76_T | 1.223 | 0.98 | |
| 42_L | 46_L | 1.218 | 0.98 | |
| 14_L | 51_A | 1.217 | 0.98 | |
| 13_A | 71_F | 1.195 | 0.98 | |
| 34_R | 37_F | 1.177 | 0.98 | |
| 104_I | 108_L | 1.153 | 0.97 | |
| 67_L | 71_F | 1.146 | 0.97 | |
| 96_L | 106_V | 1.135 | 0.97 | |
| 23_N | 45_V | 1.134 | 0.97 | |
| 24_V | 28_F | 1.118 | 0.96 | |
| 80_G | 86_Q | 1.116 | 0.96 | |
| 50_S | 54_Q | 1.11 | 0.96 | |
| 17_V | 75_A | 1.104 | 0.96 | |
| 52_L | 64_A | 1.069 | 0.95 | |
| 8_H | 58_G | 1.062 | 0.95 | |
| 55_A | 64_A | 1.059 | 0.95 | |
| 18_L | 44_A | 1.057 | 0.95 | |
| 33_R | 37_F | 1.029 | 0.94 | |
| 66_A | 69_G | 1.012 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3b5dA | 2 | 0.9541 | 99.9 | 0.315 | Contact Map | 0.087 |
| 2i68A | 2 | 0.9541 | 99.9 | 0.349 | Contact Map | 0.026 |
| 2kr6A | 1 | 0.633 | 3.2 | 0.937 | Contact Map | 0.002 |
| 3rqwA | 10 | 0.5505 | 2.5 | 0.941 | Contact Map | 0.134 |
| 2ls4A | 1 | 0.2202 | 2.3 | 0.942 | Contact Map | 0.082 |
| 3effK | 4 | 0.7339 | 1.9 | 0.945 | Contact Map | 0.239 |
| 1pw4A | 1 | 1 | 1.9 | 0.945 | Contact Map | 0.243 |
| 4ikvA | 1 | 0.9908 | 1.4 | 0.948 | Contact Map | 0.276 |
| 4apsA | 2 | 0.9908 | 1.4 | 0.949 | Contact Map | 0.304 |
| 2xutA | 3 | 1 | 1.4 | 0.949 | Contact Map | 0.217 |
Sequence Conservation (Image Generated using WebLogo v3)