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YGEY - Uncharacterized protein YgeY
UniProt: P65807 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13055
Length: 403 (382)
Sequences: 12975
Seq/Len: 33.97
YGEY
Paralog alert: 0.89 [within 20: 0.21] - ratio of genomes with paralogs
Cluster includes: ABGA ABGB ALLC ARGE DAPE PEPT YGEY
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
193_D 257_S 3.293 1.00
68_Y 141_L 3.153 1.00
46_K 50_E 3.088 1.00
199_C 207_G 3.079 1.00
193_D 259_A 2.919 1.00
195_Q 291_V 2.763 1.00
330_N 398_S 2.715 1.00
276_L 280_R 2.695 1.00
277_D 281_A 2.69 1.00
334_G 398_S 2.687 1.00
194_V 217_I 2.682 1.00
280_R 284_A 2.675 1.00
213_K 290_A 2.596 1.00
27_D 44_R 2.573 1.00
191_R 259_A 2.554 1.00
94_D 377_N 2.536 1.00
214_M 244_I 2.532 1.00
48_E 51_K 2.484 1.00
106_L 379_K 2.481 1.00
334_G 394_A 2.459 1.00
195_Q 257_S 2.414 1.00
75_L 139_T 2.414 1.00
333_E 339_A 2.408 1.00
193_D 293_S 2.401 1.00
214_M 258_C 2.303 1.00
214_M 260_V 2.285 1.00
47_E 51_K 2.227 1.00
191_R 261_S 2.18 1.00
215_G 218_L 2.12 1.00
43_H 47_E 2.099 1.00
394_A 397_L 2.09 1.00
191_R 308_P 2.089 1.00
49_M 67_G 2.037 1.00
245_F 259_A 2.035 1.00
45_I 82_I 2.03 1.00
39_K 43_H 2.011 1.00
329_V 333_E 2 1.00
40_R 43_H 1.986 1.00
20_D 127_K 1.981 1.00
95_F 103_T 1.959 1.00
195_Q 293_S 1.948 1.00
27_D 40_R 1.923 1.00
128_I 132_L 1.915 1.00
44_R 48_E 1.911 1.00
52_V 127_K 1.907 1.00
217_I 283_P 1.885 1.00
105_E 383_S 1.838 1.00
96_D 99_E 1.83 1.00
328_L 395_I 1.825 1.00
157_Q 161_E 1.812 1.00
278_E 281_A 1.793 1.00
31_I 44_R 1.78 1.00
21_M 389_A 1.778 1.00
197_V 208_D 1.772 1.00
273_E 277_D 1.766 1.00
128_I 393_A 1.757 1.00
77_A 167_P 1.751 1.00
247_T 258_C 1.717 1.00
95_F 99_E 1.693 1.00
19_A 23_R 1.687 1.00
331_A 398_S 1.682 1.00
208_D 290_A 1.667 1.00
23_R 27_D 1.656 1.00
355_M 362_V 1.656 1.00
46_K 65_V 1.649 1.00
27_D 30_A 1.645 1.00
335_L 394_A 1.642 1.00
274_G 278_E 1.623 1.00
216_P 219_G 1.623 1.00
326_K 329_V 1.621 1.00
208_D 213_K 1.62 1.00
68_Y 139_T 1.609 1.00
121_S 388_C 1.604 1.00
75_L 141_L 1.596 1.00
210_A 258_C 1.591 1.00
271_T 274_G 1.588 1.00
21_M 124_Y 1.583 1.00
198_S 256_D 1.575 1.00
47_E 50_E 1.571 1.00
54_F 69_I 1.556 1.00
243_E 261_S 1.555 1.00
193_D 308_P 1.541 1.00
211_I 244_I 1.534 1.00
78_M 122_M 1.533 1.00
215_G 219_G 1.532 1.00
194_V 214_M 1.529 1.00
48_E 52_V 1.526 1.00
127_K 131_D 1.525 1.00
77_A 143_T 1.512 1.00
42_V 82_I 1.508 1.00
216_P 288_A 1.506 1.00
158_Y 161_E 1.468 1.00
18_Q 386_V 1.456 1.00
26_R 30_A 1.447 1.00
46_K 58_E 1.437 1.00
44_R 47_E 1.427 1.00
21_M 120_A 1.422 1.00
33_S 41_V 1.421 1.00
24_F 48_E 1.417 1.00
274_G 277_D 1.399 0.99
29_V 109_G 1.374 0.99
194_V 213_K 1.358 0.99
387_T 390_A 1.347 0.99
235_G 268_W 1.342 0.99
192_I 260_V 1.333 0.99
283_P 292_V 1.33 0.99
332_Y 391_M 1.326 0.99
331_A 394_A 1.315 0.99
102_E 382_K 1.306 0.99
212_F 222_Q 1.299 0.99
26_R 102_E 1.293 0.99
26_R 382_K 1.291 0.99
386_V 390_A 1.29 0.99
394_A 398_S 1.285 0.99
24_F 44_R 1.284 0.99
78_M 396_P 1.283 0.99
276_L 311_C 1.276 0.99
45_I 119_M 1.273 0.99
27_D 31_I 1.261 0.99
281_A 285_V 1.25 0.99
69_I 130_K 1.24 0.98
169_F 399_W 1.239 0.98
43_H 58_E 1.238 0.98
15_K 390_A 1.238 0.98
277_D 280_R 1.226 0.98
26_R 100_G 1.217 0.98
190_I 262_I 1.213 0.98
23_R 26_R 1.213 0.98
220_E 285_V 1.211 0.98
325_V 363_I 1.211 0.98
188_M 272_W 1.209 0.98
50_E 58_E 1.202 0.98
330_N 334_G 1.201 0.98
24_F 124_Y 1.201 0.98
22_T 26_R 1.2 0.98
192_I 217_I 1.196 0.98
30_A 99_E 1.195 0.98
326_K 330_N 1.193 0.98
13_K 17_Y 1.189 0.98
39_K 63_G 1.187 0.98
212_F 223_E 1.187 0.98
17_Y 20_D 1.187 0.98
29_V 112_T 1.178 0.98
218_L 260_V 1.176 0.98
327_A 331_A 1.171 0.98
12_E 16_D 1.168 0.97
383_S 387_T 1.165 0.97
80_A 115_Q 1.164 0.97
50_E 56_K 1.163 0.97
237_G 275_A 1.163 0.97
244_I 258_C 1.158 0.97
130_K 133_G 1.157 0.97
80_A 119_M 1.146 0.97
43_H 46_K 1.133 0.97
190_I 276_L 1.127 0.97
20_D 23_R 1.126 0.97
40_R 44_R 1.123 0.97
194_V 260_V 1.12 0.96
42_V 65_V 1.117 0.96
229_G 278_E 1.116 0.96
46_K 56_K 1.115 0.96
125_A 393_A 1.113 0.96
327_A 398_S 1.111 0.96
105_E 381_W 1.11 0.96
330_N 333_E 1.106 0.96
220_E 223_E 1.104 0.96
28_M 41_V 1.101 0.96
331_A 335_L 1.096 0.96
212_F 218_L 1.093 0.96
55_D 68_Y 1.092 0.96
280_R 307_Y 1.091 0.96
102_E 105_E 1.08 0.95
18_Q 383_S 1.076 0.95
24_F 127_K 1.075 0.95
122_M 142_V 1.075 0.95
322_H 326_K 1.068 0.95
28_M 44_R 1.058 0.95
77_A 170_V 1.058 0.95
276_L 309_T 1.055 0.95
220_E 282_L 1.055 0.95
221_L 279_I 1.052 0.95
35_S 150_D 1.05 0.94
218_L 244_I 1.05 0.94
30_A 102_E 1.045 0.94
195_Q 256_D 1.041 0.94
158_Y 162_Q 1.041 0.94
21_M 385_L 1.023 0.93
82_I 119_M 1.022 0.93
106_L 381_W 1.021 0.93
216_P 287_K 1.018 0.93
381_W 384_H 1.017 0.93
138_Y 400_L 1.016 0.93
192_I 307_Y 1.015 0.93
328_L 363_I 1.009 0.93
219_G 223_E 1.008 0.93
329_V 342_V 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3pfoA20.95781000.204Contact Map0.707
1vgyA20.91811000.255Contact Map0.708
3iszA20.90821000.257Contact Map0.803
4g1pA10.96031000.278Contact Map0.714
1cg2A40.9281000.282Contact Map0.68
2pokA20.95041000.283Contact Map0.699
2zogA20.95291000.286Contact Map0.678
3io1A20.92311000.286Contact Map0.718
3rzaA20.91561000.291Contact Map0.749
3dljA20.95531000.293Contact Map0.64
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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