| UniProt: | P29745 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11549 | ||
| Length: | 408 (382) | ||
| Sequences: | 12839 | ||
| Seq/Len: | 33.61 |
| PEPT
Paralog alert: 0.89 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: ABGA ABGB ALLC ARGE DAPE PEPT YGEY |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 216_K | 272_R | 3.192 | 1.00 | |
| 218_V | 310_Y | 3.151 | 1.00 | |
| 61_T | 166_R | 3.141 | 1.00 | |
| 39_K | 43_E | 3.083 | 1.00 | |
| 222_V | 231_M | 3.044 | 1.00 | |
| 237_L | 309_C | 2.875 | 1.00 | |
| 295_M | 299_K | 2.862 | 1.00 | |
| 216_K | 312_E | 2.822 | 1.00 | |
| 216_K | 274_D | 2.789 | 1.00 | |
| 292_R | 296_E | 2.754 | 1.00 | |
| 338_Q | 403_L | 2.722 | 1.00 | |
| 342_D | 403_L | 2.639 | 1.00 | |
| 10_N | 37_L | 2.606 | 1.00 | |
| 217_I | 241_I | 2.606 | 1.00 | |
| 214_N | 314_V | 2.554 | 1.00 | |
| 291_K | 295_M | 2.552 | 1.00 | |
| 128_L | 384_F | 2.544 | 1.00 | |
| 342_D | 399_R | 2.486 | 1.00 | |
| 218_V | 312_E | 2.484 | 1.00 | |
| 41_Q | 44_E | 2.479 | 1.00 | |
| 72_A | 164_D | 2.434 | 1.00 | |
| 341_R | 346_E | 2.336 | 1.00 | |
| 238_A | 266_M | 2.301 | 1.00 | |
| 218_V | 272_R | 2.276 | 1.00 | |
| 214_N | 274_D | 2.258 | 1.00 | |
| 39_K | 52_L | 2.254 | 1.00 | |
| 63_P | 164_D | 2.231 | 1.00 | |
| 40_E | 44_E | 2.202 | 1.00 | |
| 238_A | 273_A | 2.139 | 1.00 | |
| 399_R | 402_E | 2.136 | 1.00 | |
| 154_V | 398_V | 2.102 | 1.00 | |
| 239_A | 242_H | 2.096 | 1.00 | |
| 36_H | 40_E | 2.087 | 1.00 | |
| 32_W | 36_H | 2.076 | 1.00 | |
| 238_A | 275_M | 2.065 | 1.00 | |
| 42_L | 60_A | 2.038 | 1.00 | |
| 45_M | 153_A | 2.012 | 1.00 | |
| 214_N | 276_H | 2.004 | 1.00 | |
| 38_L | 79_V | 1.999 | 1.00 | |
| 337_Q | 341_R | 1.998 | 1.00 | |
| 33_K | 36_H | 1.983 | 1.00 | |
| 268_G | 273_A | 1.931 | 1.00 | |
| 10_N | 33_K | 1.905 | 1.00 | |
| 216_K | 314_V | 1.894 | 1.00 | |
| 37_L | 41_Q | 1.877 | 1.00 | |
| 336_A | 400_I | 1.832 | 1.00 | |
| 241_I | 298_A | 1.824 | 1.00 | |
| 14_L | 37_L | 1.779 | 1.00 | |
| 267_K | 274_D | 1.758 | 1.00 | |
| 72_A | 166_R | 1.754 | 1.00 | |
| 288_E | 292_R | 1.742 | 1.00 | |
| 10_N | 13_S | 1.74 | 1.00 | |
| 49_N | 63_P | 1.739 | 1.00 | |
| 293_K | 296_E | 1.72 | 1.00 | |
| 299_K | 303_K | 1.708 | 1.00 | |
| 90_V | 94_I | 1.694 | 1.00 | |
| 232_V | 237_L | 1.688 | 1.00 | |
| 36_H | 52_L | 1.686 | 1.00 | |
| 362_S | 368_C | 1.679 | 1.00 | |
| 154_V | 158_K | 1.678 | 1.00 | |
| 339_A | 403_L | 1.665 | 1.00 | |
| 6_E | 10_N | 1.654 | 1.00 | |
| 47_L | 50_V | 1.632 | 1.00 | |
| 221_N | 271_E | 1.619 | 1.00 | |
| 74_G | 189_A | 1.617 | 1.00 | |
| 61_T | 164_D | 1.614 | 1.00 | |
| 40_E | 43_E | 1.613 | 1.00 | |
| 127_T | 388_E | 1.611 | 1.00 | |
| 39_K | 58_L | 1.595 | 1.00 | |
| 240_R | 243_A | 1.589 | 1.00 | |
| 47_L | 62_L | 1.585 | 1.00 | |
| 234_A | 273_A | 1.584 | 1.00 | |
| 35_L | 79_V | 1.578 | 1.00 | |
| 235_L | 266_M | 1.577 | 1.00 | |
| 74_G | 168_A | 1.575 | 1.00 | |
| 147_E | 393_A | 1.574 | 1.00 | |
| 334_D | 337_Q | 1.569 | 1.00 | |
| 43_E | 52_L | 1.566 | 1.00 | |
| 39_K | 50_V | 1.565 | 1.00 | |
| 240_R | 306_H | 1.564 | 1.00 | |
| 220_N | 232_V | 1.564 | 1.00 | |
| 232_V | 309_C | 1.563 | 1.00 | |
| 75_F | 148_I | 1.524 | 1.00 | |
| 9_L | 13_S | 1.504 | 1.00 | |
| 41_Q | 45_M | 1.494 | 1.00 | |
| 289_A | 293_K | 1.492 | 1.00 | |
| 217_I | 238_A | 1.482 | 1.00 | |
| 265_S | 276_H | 1.48 | 1.00 | |
| 286_Q | 289_A | 1.47 | 1.00 | |
| 239_A | 243_A | 1.455 | 1.00 | |
| 7_R | 41_Q | 1.446 | 1.00 | |
| 32_W | 56_G | 1.445 | 1.00 | |
| 66_V | 69_D | 1.431 | 1.00 | |
| 12_V | 131_T | 1.43 | 1.00 | |
| 9_L | 387_L | 1.43 | 1.00 | |
| 298_A | 311_I | 1.422 | 1.00 | |
| 180_K | 184_V | 1.422 | 1.00 | |
| 302_G | 311_I | 1.408 | 1.00 | |
| 37_L | 40_E | 1.405 | 0.99 | |
| 18_S | 175_V | 1.398 | 0.99 | |
| 211_A | 287_F | 1.394 | 0.99 | |
| 4_L | 394_V | 1.394 | 0.99 | |
| 257_Y | 283_D | 1.383 | 0.99 | |
| 16_T | 34_L | 1.378 | 0.99 | |
| 49_N | 61_T | 1.368 | 0.99 | |
| 77_S | 141_D | 1.357 | 0.99 | |
| 43_E | 50_V | 1.347 | 0.99 | |
| 392_K | 395_Q | 1.346 | 0.99 | |
| 399_R | 403_L | 1.343 | 0.99 | |
| 391_E | 395_Q | 1.343 | 0.99 | |
| 7_R | 37_L | 1.341 | 0.99 | |
| 217_I | 237_L | 1.333 | 0.99 | |
| 153_A | 157_Q | 1.328 | 0.99 | |
| 13_S | 96_E | 1.327 | 0.99 | |
| 3_K | 153_A | 1.32 | 0.99 | |
| 62_L | 156_Q | 1.32 | 0.99 | |
| 143_A | 385_V | 1.318 | 0.99 | |
| 240_R | 304_G | 1.317 | 0.99 | |
| 340_M | 396_V | 1.308 | 0.99 | |
| 148_I | 167_V | 1.307 | 0.99 | |
| 75_F | 401_A | 1.305 | 0.99 | |
| 339_A | 399_R | 1.3 | 0.99 | |
| 143_A | 390_M | 1.291 | 0.99 | |
| 66_V | 162_H | 1.288 | 0.99 | |
| 38_L | 145_I | 1.283 | 0.99 | |
| 289_A | 292_R | 1.274 | 0.99 | |
| 156_Q | 159_K | 1.273 | 0.99 | |
| 215_I | 275_M | 1.271 | 0.99 | |
| 334_D | 338_Q | 1.265 | 0.99 | |
| 214_N | 316_E | 1.258 | 0.99 | |
| 99_R | 382_H | 1.252 | 0.99 | |
| 7_R | 150_T | 1.245 | 0.98 | |
| 291_K | 315_I | 1.241 | 0.98 | |
| 4_L | 146_A | 1.24 | 0.98 | |
| 296_E | 300_K | 1.24 | 0.98 | |
| 236_S | 246_P | 1.231 | 0.98 | |
| 10_N | 14_L | 1.225 | 0.98 | |
| 292_R | 295_M | 1.211 | 0.98 | |
| 215_I | 241_I | 1.21 | 0.98 | |
| 336_A | 369_P | 1.209 | 0.98 | |
| 51_T | 186_A | 1.2 | 0.98 | |
| 343_C | 399_R | 1.198 | 0.98 | |
| 213_V | 277_Y | 1.197 | 0.98 | |
| 335_I | 339_A | 1.189 | 0.98 | |
| 5_L | 9_L | 1.187 | 0.98 | |
| 11_Y | 34_L | 1.186 | 0.98 | |
| 12_V | 134_K | 1.181 | 0.98 | |
| 215_I | 313_L | 1.179 | 0.98 | |
| 50_V | 60_A | 1.174 | 0.98 | |
| 295_M | 313_L | 1.174 | 0.98 | |
| 181_H | 184_V | 1.17 | 0.97 | |
| 101_G | 104_A | 1.166 | 0.97 | |
| 291_K | 317_D | 1.165 | 0.97 | |
| 338_Q | 342_D | 1.162 | 0.97 | |
| 227_A | 230_V | 1.161 | 0.97 | |
| 6_E | 9_L | 1.156 | 0.97 | |
| 330_P | 334_D | 1.155 | 0.97 | |
| 335_I | 403_L | 1.154 | 0.97 | |
| 337_Q | 349_L | 1.15 | 0.97 | |
| 252_E | 293_K | 1.141 | 0.97 | |
| 151_A | 398_V | 1.14 | 0.97 | |
| 33_K | 37_L | 1.137 | 0.97 | |
| 388_E | 392_K | 1.135 | 0.97 | |
| 236_S | 247_A | 1.124 | 0.97 | |
| 7_R | 153_A | 1.121 | 0.97 | |
| 244_E | 300_K | 1.118 | 0.96 | |
| 35_L | 58_L | 1.116 | 0.96 | |
| 338_Q | 341_R | 1.115 | 0.96 | |
| 235_L | 268_G | 1.108 | 0.96 | |
| 71_P | 190_R | 1.101 | 0.96 | |
| 4_L | 150_T | 1.101 | 0.96 | |
| 191_W | 404_T | 1.1 | 0.96 | |
| 11_Y | 37_L | 1.096 | 0.96 | |
| 296_E | 299_K | 1.094 | 0.96 | |
| 128_L | 386_T | 1.089 | 0.96 | |
| 88_K | 91_N | 1.087 | 0.96 | |
| 266_M | 273_A | 1.086 | 0.96 | |
| 213_V | 291_K | 1.086 | 0.96 | |
| 2_D | 6_E | 1.082 | 0.96 | |
| 154_V | 395_Q | 1.081 | 0.95 | |
| 96_E | 125_G | 1.072 | 0.95 | |
| 386_T | 389_G | 1.071 | 0.95 | |
| 74_G | 192_A | 1.071 | 0.95 | |
| 36_H | 39_K | 1.067 | 0.95 | |
| 41_Q | 153_A | 1.067 | 0.95 | |
| 79_V | 145_I | 1.052 | 0.95 | |
| 333_L | 369_P | 1.049 | 0.94 | |
| 300_K | 304_G | 1.048 | 0.94 | |
| 242_H | 275_M | 1.045 | 0.94 | |
| 64_A | 164_D | 1.045 | 0.94 | |
| 339_A | 400_I | 1.041 | 0.94 | |
| 72_A | 190_R | 1.03 | 0.94 | |
| 10_N | 41_Q | 1.01 | 0.93 | |
| 236_S | 242_H | 1.009 | 0.93 | |
| 43_E | 49_N | 1.004 | 0.93 | |
| 395_Q | 399_R | 1.004 | 0.93 | |
| 158_K | 402_E | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1fnoA | 1 | 1 | 100 | 0.247 | Contact Map | 0.725 |
| 3ifeA | 1 | 0.9951 | 100 | 0.249 | Contact Map | 0.743 |
| 3pfoA | 2 | 0.8848 | 100 | 0.269 | Contact Map | 0.726 |
| 3rzaA | 2 | 0.8701 | 100 | 0.273 | Contact Map | 0.749 |
| 3gb0A | 1 | 0.8652 | 100 | 0.277 | Contact Map | 0.733 |
| 3iszA | 2 | 0.8652 | 100 | 0.3 | Contact Map | 0.792 |
| 1vgyA | 2 | 0.8676 | 100 | 0.305 | Contact Map | 0.719 |
| 1cg2A | 4 | 0.8725 | 100 | 0.315 | Contact Map | 0.697 |
| 2qyvA | 2 | 0.8799 | 100 | 0.328 | Contact Map | 0.663 |
| 4g1pA | 1 | 0.9069 | 100 | 0.338 | Contact Map | 0.728 |
Sequence Conservation (Image Generated using WebLogo v3)