| UniProt: | P46888 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12862 | ||
| Length: | 142 (139) | ||
| Sequences: | 6568 | ||
| Seq/Len: | 47.25 |
| USPC
Paralog alert: 0.77 [within 20: 0.26] - ratio of genomes with paralogs Cluster includes: USPA USPC USPD USPF USPG |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 5_N | 35_S | 2.712 | 1.00 | |
| 5_N | 33_H | 2.621 | 1.00 | |
| 105_L | 135_L | 2.451 | 1.00 | |
| 91_S | 125_R | 2.432 | 1.00 | |
| 33_H | 82_K | 2.414 | 1.00 | |
| 124_K | 128_A | 2.356 | 1.00 | |
| 9_A | 108_C | 2.335 | 1.00 | |
| 7_L | 103_F | 2.289 | 1.00 | |
| 35_S | 84_F | 2.275 | 1.00 | |
| 97_V | 101_H | 2.123 | 1.00 | |
| 98_C | 106_V | 2.106 | 1.00 | |
| 108_C | 126_V | 2.079 | 1.00 | |
| 110_N | 138_P | 1.939 | 1.00 | |
| 35_S | 101_H | 1.896 | 1.00 | |
| 88_G | 93_H | 1.891 | 1.00 | |
| 22_K | 135_L | 1.884 | 1.00 | |
| 84_F | 97_V | 1.806 | 1.00 | |
| 35_S | 103_F | 1.732 | 1.00 | |
| 99_H | 131_E | 1.695 | 1.00 | |
| 106_V | 130_S | 1.688 | 1.00 | |
| 86_A | 93_H | 1.68 | 1.00 | |
| 8_V | 23_A | 1.675 | 1.00 | |
| 35_S | 97_V | 1.665 | 1.00 | |
| 93_H | 96_E | 1.638 | 1.00 | |
| 110_N | 136_L | 1.622 | 1.00 | |
| 66_Q | 70_D | 1.593 | 1.00 | |
| 3_Y | 22_K | 1.585 | 1.00 | |
| 127_I | 136_L | 1.556 | 1.00 | |
| 9_A | 94_I | 1.555 | 1.00 | |
| 38_T | 65_T | 1.532 | 1.00 | |
| 21_A | 75_D | 1.509 | 1.00 | |
| 73_I | 83_T | 1.482 | 1.00 | |
| 23_A | 27_A | 1.48 | 1.00 | |
| 37_I | 97_V | 1.383 | 0.99 | |
| 39_L | 93_H | 1.369 | 0.99 | |
| 106_V | 132_V | 1.35 | 0.99 | |
| 20_L | 72_L | 1.341 | 0.99 | |
| 95_L | 129_S | 1.339 | 0.99 | |
| 37_I | 94_I | 1.329 | 0.99 | |
| 62_H | 66_Q | 1.32 | 0.99 | |
| 130_S | 134_V | 1.277 | 0.99 | |
| 26_I | 30_V | 1.261 | 0.99 | |
| 95_L | 126_V | 1.258 | 0.99 | |
| 98_C | 131_E | 1.253 | 0.99 | |
| 22_K | 133_D | 1.25 | 0.99 | |
| 58_R | 62_H | 1.242 | 0.98 | |
| 125_R | 129_S | 1.24 | 0.98 | |
| 8_V | 20_L | 1.239 | 0.98 | |
| 22_K | 25_S | 1.219 | 0.98 | |
| 3_Y | 133_D | 1.215 | 0.98 | |
| 123_A | 136_L | 1.206 | 0.98 | |
| 16_S | 19_L | 1.205 | 0.98 | |
| 13_T | 112_N | 1.201 | 0.98 | |
| 25_S | 29_P | 1.19 | 0.98 | |
| 17_Q | 75_D | 1.185 | 0.98 | |
| 13_T | 16_S | 1.166 | 0.97 | |
| 35_S | 82_K | 1.158 | 0.97 | |
| 95_L | 98_C | 1.152 | 0.97 | |
| 84_F | 101_H | 1.137 | 0.97 | |
| 96_E | 100_K | 1.127 | 0.97 | |
| 94_I | 126_V | 1.125 | 0.97 | |
| 90_L | 122_S | 1.119 | 0.96 | |
| 6_I | 105_L | 1.104 | 0.96 | |
| 68_F | 72_L | 1.104 | 0.96 | |
| 5_N | 103_F | 1.092 | 0.96 | |
| 23_A | 34_I | 1.089 | 0.96 | |
| 112_N | 115_F | 1.087 | 0.96 | |
| 86_A | 97_V | 1.082 | 0.96 | |
| 5_N | 104_D | 1.07 | 0.95 | |
| 106_V | 126_V | 1.065 | 0.95 | |
| 24_V | 76_A | 1.058 | 0.95 | |
| 10_V | 72_L | 1.057 | 0.95 | |
| 70_D | 83_T | 1.042 | 0.94 | |
| 70_D | 74_Q | 1.021 | 0.93 | |
| 12_V | 72_L | 1.015 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3tnjA | 1 | 0.993 | 99.9 | 0.125 | Contact Map | 0.781 |
| 2dumA | 4 | 0.993 | 99.9 | 0.151 | Contact Map | 0.785 |
| 3s3tA | 8 | 0.9718 | 99.9 | 0.158 | Contact Map | 0.711 |
| 1jmvA | 4 | 0.9859 | 99.9 | 0.162 | Contact Map | 0.792 |
| 1mjhA | 2 | 1 | 99.9 | 0.166 | Contact Map | 0.876 |
| 3fg9A | 6 | 0.9577 | 99.9 | 0.186 | Contact Map | 0.686 |
| 3olqA | 1 | 1 | 99.9 | 0.187 | Contact Map | 0.752 |
| 2gm3A | 6 | 1 | 99.9 | 0.193 | Contact Map | 0.827 |
| 2z08A | 1 | 0.9507 | 99.9 | 0.195 | Contact Map | 0.743 |
| 3hgmA | 4 | 0.9577 | 99.9 | 0.196 | Contact Map | 0.875 |
Sequence Conservation (Image Generated using WebLogo v3)