| UniProt: | P42599 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12729 | ||
| Length: | 328 (319) | ||
| Sequences: | 9073 | ||
| Seq/Len: | 28.44 |
| YGJR
Paralog alert: 0.78 [within 20: 0.22] - ratio of genomes with paralogs Cluster includes: YCEM YCJS YDGJ YGJR YHHX YJHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 56_E | 82_L | 3.277 | 1.00 | |
| 81_Q | 109_C | 3.054 | 1.00 | |
| 131_L | 134_Q | 3.004 | 1.00 | |
| 141_K | 243_E | 2.941 | 1.00 | |
| 3_R | 27_K | 2.911 | 1.00 | |
| 36_L | 40_Q | 2.858 | 1.00 | |
| 84_L | 115_V | 2.807 | 1.00 | |
| 197_S | 218_D | 2.702 | 1.00 | |
| 77_F | 105_A | 2.674 | 1.00 | |
| 81_Q | 85_S | 2.659 | 1.00 | |
| 124_A | 186_A | 2.658 | 1.00 | |
| 85_S | 109_C | 2.611 | 1.00 | |
| 104_D | 304_R | 2.548 | 1.00 | |
| 81_Q | 105_A | 2.364 | 1.00 | |
| 133_R | 137_P | 2.345 | 1.00 | |
| 40_Q | 44_N | 2.344 | 1.00 | |
| 104_D | 308_K | 2.311 | 1.00 | |
| 54_S | 57_A | 2.311 | 1.00 | |
| 71_S | 79_Q | 2.3 | 1.00 | |
| 66_A | 286_F | 2.294 | 1.00 | |
| 77_F | 102_E | 2.252 | 1.00 | |
| 108_A | 112_E | 2.246 | 1.00 | |
| 196_K | 220_G | 2.232 | 1.00 | |
| 5_A | 58_M | 2.229 | 1.00 | |
| 109_C | 113_N | 2.225 | 1.00 | |
| 77_F | 81_Q | 2.197 | 1.00 | |
| 75_L | 79_Q | 2.182 | 1.00 | |
| 30_A | 52_F | 2.175 | 1.00 | |
| 288_T | 292_E | 2.155 | 1.00 | |
| 80_T | 92_C | 2.132 | 1.00 | |
| 111_R | 301_A | 2.087 | 1.00 | |
| 89_N | 116_V | 2.065 | 1.00 | |
| 131_L | 135_A | 2.065 | 1.00 | |
| 139_V | 242_G | 2.047 | 1.00 | |
| 215_V | 313_I | 2.016 | 1.00 | |
| 85_S | 113_N | 2.004 | 1.00 | |
| 104_D | 108_A | 1.938 | 1.00 | |
| 25_K | 291_D | 1.934 | 1.00 | |
| 84_L | 110_A | 1.932 | 1.00 | |
| 53_T | 57_A | 1.88 | 1.00 | |
| 132_L | 247_L | 1.843 | 1.00 | |
| 50_H | 61_S | 1.842 | 1.00 | |
| 71_S | 75_L | 1.824 | 1.00 | |
| 14_R | 45_D | 1.81 | 1.00 | |
| 64_I | 88_I | 1.785 | 1.00 | |
| 116_V | 293_H | 1.781 | 1.00 | |
| 78_S | 82_L | 1.751 | 1.00 | |
| 85_S | 112_E | 1.75 | 1.00 | |
| 35_S | 38_Q | 1.742 | 1.00 | |
| 26_Y | 287_A | 1.73 | 1.00 | |
| 67_V | 83_F | 1.724 | 1.00 | |
| 142_L | 240_I | 1.721 | 1.00 | |
| 99_N | 102_E | 1.721 | 1.00 | |
| 80_T | 106_A | 1.717 | 1.00 | |
| 89_N | 115_V | 1.695 | 1.00 | |
| 97_A | 106_A | 1.694 | 1.00 | |
| 312_E | 316_Q | 1.694 | 1.00 | |
| 5_A | 64_I | 1.644 | 1.00 | |
| 4_F | 66_A | 1.63 | 1.00 | |
| 3_R | 65_D | 1.621 | 1.00 | |
| 77_F | 106_A | 1.61 | 1.00 | |
| 20_A | 68_Y | 1.605 | 1.00 | |
| 185_L | 309_L | 1.591 | 1.00 | |
| 285_L | 289_L | 1.57 | 1.00 | |
| 58_M | 64_I | 1.548 | 1.00 | |
| 98_S | 102_E | 1.545 | 1.00 | |
| 196_K | 218_D | 1.544 | 1.00 | |
| 59_A | 83_F | 1.525 | 1.00 | |
| 23_S | 284_E | 1.52 | 1.00 | |
| 120_A | 282_E | 1.519 | 1.00 | |
| 117_L | 300_L | 1.508 | 1.00 | |
| 52_F | 61_S | 1.504 | 1.00 | |
| 143_R | 243_E | 1.498 | 1.00 | |
| 146_F | 239_E | 1.475 | 1.00 | |
| 60_E | 86_H | 1.461 | 1.00 | |
| 41_H | 45_D | 1.459 | 1.00 | |
| 219_Y | 224_V | 1.452 | 1.00 | |
| 135_A | 138_K | 1.434 | 1.00 | |
| 133_R | 190_A | 1.426 | 1.00 | |
| 108_A | 111_R | 1.42 | 1.00 | |
| 288_T | 294_L | 1.402 | 0.99 | |
| 139_V | 245_G | 1.393 | 0.99 | |
| 84_L | 113_N | 1.392 | 0.99 | |
| 52_F | 58_M | 1.39 | 0.99 | |
| 57_A | 60_E | 1.376 | 0.99 | |
| 107_I | 304_R | 1.375 | 0.99 | |
| 195_P | 219_Y | 1.362 | 0.99 | |
| 56_E | 60_E | 1.359 | 0.99 | |
| 89_N | 290_V | 1.358 | 0.99 | |
| 30_A | 58_M | 1.345 | 0.99 | |
| 69_I | 80_T | 1.344 | 0.99 | |
| 109_C | 112_E | 1.341 | 0.99 | |
| 97_A | 103_V | 1.337 | 0.99 | |
| 285_L | 297_H | 1.336 | 0.99 | |
| 107_I | 300_L | 1.329 | 0.99 | |
| 105_A | 108_A | 1.326 | 0.99 | |
| 189_V | 194_E | 1.324 | 0.99 | |
| 305_I | 308_K | 1.323 | 0.99 | |
| 55_L | 82_L | 1.315 | 0.99 | |
| 82_L | 85_S | 1.314 | 0.99 | |
| 194_E | 220_G | 1.312 | 0.99 | |
| 100_L | 311_T | 1.294 | 0.99 | |
| 3_R | 29_T | 1.289 | 0.99 | |
| 84_L | 90_V | 1.288 | 0.99 | |
| 83_F | 90_V | 1.287 | 0.99 | |
| 9_T | 31_V | 1.284 | 0.99 | |
| 239_E | 248_V | 1.281 | 0.99 | |
| 87_K | 113_N | 1.274 | 0.99 | |
| 185_L | 310_L | 1.257 | 0.99 | |
| 55_L | 59_A | 1.249 | 0.99 | |
| 69_I | 79_Q | 1.248 | 0.99 | |
| 39_A | 51_L | 1.247 | 0.99 | |
| 100_L | 104_D | 1.243 | 0.98 | |
| 63_A | 88_I | 1.234 | 0.98 | |
| 62_D | 88_I | 1.234 | 0.98 | |
| 82_L | 86_H | 1.234 | 0.98 | |
| 32_Y | 55_L | 1.221 | 0.98 | |
| 36_L | 53_T | 1.22 | 0.98 | |
| 84_L | 109_C | 1.218 | 0.98 | |
| 39_A | 43_A | 1.216 | 0.98 | |
| 81_Q | 106_A | 1.214 | 0.98 | |
| 105_A | 109_C | 1.211 | 0.98 | |
| 139_V | 142_L | 1.207 | 0.98 | |
| 237_A | 248_V | 1.198 | 0.98 | |
| 2_I | 66_A | 1.197 | 0.98 | |
| 37_E | 40_Q | 1.181 | 0.98 | |
| 102_E | 105_A | 1.181 | 0.98 | |
| 106_A | 117_L | 1.175 | 0.98 | |
| 103_V | 304_R | 1.172 | 0.98 | |
| 311_T | 315_R | 1.156 | 0.97 | |
| 2_I | 290_V | 1.155 | 0.97 | |
| 32_Y | 58_M | 1.143 | 0.97 | |
| 72_P | 75_L | 1.141 | 0.97 | |
| 189_V | 305_I | 1.126 | 0.97 | |
| 194_E | 305_I | 1.126 | 0.97 | |
| 312_E | 315_R | 1.122 | 0.97 | |
| 57_A | 61_S | 1.109 | 0.96 | |
| 55_L | 79_Q | 1.108 | 0.96 | |
| 201_T | 218_D | 1.107 | 0.96 | |
| 100_L | 308_K | 1.101 | 0.96 | |
| 61_S | 64_I | 1.101 | 0.96 | |
| 139_V | 247_L | 1.099 | 0.96 | |
| 92_C | 117_L | 1.092 | 0.96 | |
| 287_A | 291_D | 1.081 | 0.95 | |
| 61_S | 88_I | 1.077 | 0.95 | |
| 41_H | 44_N | 1.072 | 0.95 | |
| 96_L | 103_V | 1.065 | 0.95 | |
| 4_F | 26_Y | 1.065 | 0.95 | |
| 199_Q | 216_V | 1.063 | 0.95 | |
| 22_E | 280_L | 1.058 | 0.95 | |
| 189_V | 302_V | 1.057 | 0.95 | |
| 91_I | 120_A | 1.056 | 0.95 | |
| 97_A | 102_E | 1.042 | 0.94 | |
| 30_A | 64_I | 1.04 | 0.94 | |
| 195_P | 217_M | 1.031 | 0.94 | |
| 188_A | 224_V | 1.028 | 0.94 | |
| 125_C | 285_L | 1.026 | 0.94 | |
| 284_E | 288_T | 1.024 | 0.93 | |
| 192_F | 222_F | 1.019 | 0.93 | |
| 80_T | 84_L | 1.016 | 0.93 | |
| 5_A | 32_Y | 1.014 | 0.93 | |
| 299_G | 302_V | 1.007 | 0.93 | |
| 59_A | 86_H | 1.006 | 0.93 | |
| 189_V | 219_Y | 1.005 | 0.93 | |
| 1_M | 27_K | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zh8A | 2 | 0.9604 | 100 | 0.197 | Contact Map | 0.8 |
| 1h6dA | 12 | 0.9848 | 100 | 0.202 | Contact Map | 0.775 |
| 4nheA | 3 | 0.9787 | 100 | 0.202 | Contact Map | 0.794 |
| 3ohsX | 1 | 0.9604 | 100 | 0.207 | Contact Map | 0.8 |
| 2ho3A | 4 | 0.9787 | 100 | 0.209 | Contact Map | 0.798 |
| 2nvwA | 2 | 0.997 | 100 | 0.21 | Contact Map | 0.783 |
| 3e9mA | 4 | 0.9756 | 100 | 0.212 | Contact Map | 0.841 |
| 3dtyA | 4 | 0.997 | 100 | 0.219 | Contact Map | 0.785 |
| 4hadA | 4 | 0.9665 | 100 | 0.223 | Contact Map | 0.757 |
| 3v5nA | 4 | 0.9878 | 100 | 0.224 | Contact Map | 0.738 |
Sequence Conservation (Image Generated using WebLogo v3)