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FECD - Fe(3+) dicitrate transport system permease protein FecD
UniProt: P15029 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10289
Length: 318 (302)
Sequences: 6165
Seq/Len: 20.41
FECD
Paralog alert: 0.86 [within 20: 0.62] - ratio of genomes with paralogs
Cluster includes: BTUC FECC FECD FEPD FEPG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
205_D 264_R 5.221 1.00
63_A 273_A 4.185 1.00
71_L 228_A 3.277 1.00
59_L 277_A 3.184 1.00
220_S 223_H 3.149 1.00
99_A 114_L 3.097 1.00
58_A 175_L 2.977 1.00
64_A 235_M 2.954 1.00
257_M 275_T 2.908 1.00
71_L 197_S 2.824 1.00
57_L 178_R 2.701 1.00
64_A 190_M 2.658 1.00
211_D 225_R 2.524 1.00
67_V 273_A 2.469 1.00
22_H 30_W 2.408 1.00
64_A 239_G 2.405 1.00
61_V 243_C 2.36 1.00
70_V 272_S 2.33 1.00
94_L 149_W 2.327 1.00
32_A 35_T 2.303 1.00
261_T 271_V 2.231 1.00
59_L 281_V 2.223 1.00
20_S 55_L 2.145 1.00
205_D 265_H 2.138 1.00
54_R 284_D 2.095 1.00
94_L 152_L 2.086 1.00
61_V 239_G 2.076 1.00
17_A 55_L 2.049 1.00
16_C 282_V 2.022 1.00
17_A 59_L 1.955 1.00
74_G 265_H 1.931 1.00
72_I 232_A 1.915 1.00
119_G 237_S 1.888 1.00
29_P 32_A 1.835 1.00
67_V 194_L 1.827 1.00
184_K 188_P 1.785 1.00
56_L 183_V 1.775 1.00
249_I 280_L 1.771 1.00
286_L 290_I 1.687 1.00
257_M 271_V 1.684 1.00
223_H 227_W 1.679 1.00
206_L 219_V 1.653 1.00
288_R 295_E 1.651 1.00
203_D 224_T 1.65 1.00
178_R 182_F 1.63 1.00
253_V 279_L 1.621 1.00
97_V 153_T 1.61 1.00
175_L 280_L 1.61 1.00
287_A 298_V 1.61 1.00
189_L 238_T 1.568 1.00
57_L 242_A 1.556 1.00
31_R 35_T 1.536 1.00
265_H 268_L 1.533 1.00
75_I 228_A 1.526 1.00
179_D 182_F 1.504 1.00
93_S 153_T 1.477 1.00
286_L 301_L 1.449 1.00
36_D 48_M 1.444 1.00
257_M 268_L 1.439 1.00
66_A 253_V 1.432 1.00
19_L 22_H 1.431 1.00
188_P 192_L 1.421 1.00
70_V 268_L 1.408 1.00
200_F 203_D 1.405 0.99
192_L 195_P 1.393 0.99
60_F 187_I 1.383 0.99
68_A 235_M 1.375 0.99
200_F 227_W 1.368 0.99
58_A 280_L 1.348 0.99
184_K 187_I 1.338 0.99
21_L 55_L 1.333 0.99
123_L 233_V 1.323 0.99
267_R 270_P 1.311 0.99
222_P 225_R 1.304 0.99
284_D 288_R 1.293 0.99
70_V 265_H 1.28 0.99
196_L 200_F 1.276 0.99
122_G 149_W 1.271 0.99
63_A 277_A 1.267 0.99
265_H 270_P 1.262 0.99
119_G 233_V 1.257 0.99
28_V 47_L 1.255 0.99
96_S 115_A 1.254 0.99
32_A 43_H 1.253 0.99
268_L 272_S 1.248 0.99
193_F 235_M 1.221 0.98
215_T 222_P 1.211 0.98
98_G 102_L 1.211 0.98
148_C 307_A 1.205 0.98
89_N 236_T 1.198 0.98
303_A 308_P 1.189 0.98
95_A 114_L 1.188 0.98
20_S 285_L 1.174 0.98
95_A 118_G 1.172 0.98
55_L 285_L 1.172 0.98
126_L 145_L 1.17 0.97
121_A 125_L 1.169 0.97
196_L 231_L 1.168 0.97
267_R 271_V 1.165 0.97
89_N 245_P 1.151 0.97
116_F 234_A 1.15 0.97
210_G 214_A 1.149 0.97
223_H 226_F 1.139 0.97
33_L 47_L 1.138 0.97
186_A 190_M 1.127 0.97
93_S 171_L 1.126 0.97
60_F 183_V 1.124 0.97
58_A 281_V 1.123 0.97
48_M 52_L 1.116 0.96
98_G 156_L 1.108 0.96
124_I 128_M 1.108 0.96
213_R 216_T 1.104 0.96
246_I 280_L 1.098 0.96
193_F 234_A 1.096 0.96
243_C 246_I 1.094 0.96
224_T 227_W 1.093 0.96
70_V 269_L 1.092 0.96
253_V 257_M 1.089 0.96
60_F 186_A 1.089 0.96
278_L 282_V 1.083 0.96
19_L 23_M 1.082 0.96
287_A 297_P 1.078 0.95
200_F 228_A 1.077 0.95
91_A 118_G 1.076 0.95
94_L 98_G 1.073 0.95
200_F 224_T 1.073 0.95
286_L 289_I 1.069 0.95
257_M 260_I 1.066 0.95
180_W 183_V 1.061 0.95
113_L 117_A 1.06 0.95
116_F 120_M 1.049 0.94
91_A 122_G 1.045 0.94
187_I 191_I 1.041 0.94
26_I 46_V 1.036 0.94
54_R 288_R 1.032 0.94
270_P 273_A 1.027 0.94
309_W 312_W 1.019 0.93
249_I 302_T 1.018 0.93
186_A 242_A 1.014 0.93
193_F 231_L 1.011 0.93
304_I 308_P 1.011 0.93
27_P 30_W 1.007 0.93
66_A 70_V 1.007 0.93
90_H 149_W 1.006 0.93
206_L 217_L 1.005 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4g1uA20.99691000.13Contact Map0.811
2nq2A20.99061000.155Contact Map0.829
2qi9A20.9781000.161Contact Map0.817
2l9uA20.08184.90.972Contact Map0.533
2m20A20.07231.20.979Contact Map0.605
2x2vA130.21381.20.98Contact Map0.466
2l6wA20.09430.80.981Contact Map0.103
1m56D20.06290.80.982Contact Map
3rlfF10.40880.80.982Contact Map0.438
1qleD10.06290.80.982Contact Map
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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