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OPENSEQ.org
YDIK - UPF0118 inner membrane protein YdiK
UniProt: P0AFS7 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13970
Length: 370 (336)
Sequences: 4746
Seq/Len: 14.12
YDIK
Paralog alert: 0.78 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: PERM TQSA YDIK YHHT
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
230_G 245_T 4.599 1.00
232_G 284_W 4.068 1.00
54_R 58_I 3.817 1.00
46_I 208_A 2.888 1.00
279_T 283_V 2.84 1.00
314_G 334_L 2.815 1.00
56_Q 63_R 2.628 1.00
230_G 234_A 2.58 1.00
226_A 249_I 2.552 1.00
226_A 245_T 2.535 1.00
62_R 65_L 2.494 1.00
233_L 238_V 2.467 1.00
61_G 69_V 2.404 1.00
266_I 282_L 2.383 1.00
175_A 179_W 2.379 1.00
44_V 174_S 2.339 1.00
41_A 174_S 2.227 1.00
338_W 342_A 2.165 1.00
54_R 57_K 2.073 1.00
276_T 280_V 2.068 1.00
231_I 234_A 2.045 1.00
173_F 309_I 2.04 1.00
173_F 177_L 1.984 1.00
234_A 241_A 1.936 1.00
266_I 278_G 1.931 1.00
180_R 307_P 1.923 1.00
219_V 253_L 1.912 1.00
217_G 299_L 1.893 1.00
298_M 302_M 1.853 1.00
229_G 248_M 1.814 1.00
67_V 175_A 1.809 1.00
52_L 67_V 1.76 1.00
225_Q 252_C 1.738 1.00
52_L 70_M 1.679 1.00
52_L 63_R 1.672 1.00
48_T 178_Y 1.668 1.00
295_I 299_L 1.649 1.00
64_S 179_W 1.648 1.00
49_W 53_L 1.616 1.00
49_W 63_R 1.607 1.00
99_A 102_S 1.556 1.00
230_G 241_A 1.546 1.00
229_G 288_V 1.543 1.00
277_W 280_V 1.54 1.00
232_G 288_V 1.539 1.00
241_A 245_T 1.537 1.00
280_V 283_V 1.526 1.00
319_L 327_L 1.525 1.00
38_F 313_S 1.517 1.00
231_I 235_V 1.511 1.00
64_S 68_L 1.509 1.00
64_S 175_A 1.501 1.00
51_V 54_R 1.489 1.00
79_I 83_A 1.485 1.00
283_V 287_V 1.482 1.00
137_A 140_A 1.461 1.00
42_G 177_L 1.432 1.00
193_T 197_G 1.429 1.00
315_V 327_L 1.416 1.00
247_L 251_S 1.415 1.00
251_S 261_V 1.407 0.99
270_Y 278_G 1.379 0.99
51_V 70_M 1.37 0.99
244_L 265_A 1.366 0.99
288_V 291_L 1.357 0.99
156_Q 160_I 1.355 0.99
247_L 261_V 1.352 0.99
61_G 66_A 1.348 0.99
55_L 73_L 1.346 0.99
207_A 336_V 1.343 0.99
222_A 252_C 1.34 0.99
225_Q 296_R 1.336 0.99
245_T 249_I 1.331 0.99
276_T 279_T 1.328 0.99
325_I 329_I 1.325 0.99
75_V 79_I 1.32 0.99
38_F 173_F 1.317 0.99
140_A 144_P 1.314 0.99
269_L 281_L 1.312 0.99
252_C 258_P 1.309 0.99
186_Q 190_H 1.307 0.99
239_P 272_T 1.306 0.99
170_M 174_S 1.289 0.99
284_W 288_V 1.289 0.99
41_A 170_M 1.275 0.99
221_T 252_C 1.263 0.99
313_S 317_G 1.254 0.99
245_T 248_M 1.241 0.98
189_R 201_D 1.237 0.98
63_R 182_E 1.235 0.98
97_I 101_S 1.222 0.98
226_A 230_G 1.221 0.98
274_D 277_W 1.22 0.98
236_S 284_W 1.219 0.98
52_L 178_Y 1.216 0.98
52_L 66_A 1.213 0.98
233_L 244_L 1.208 0.98
56_Q 66_A 1.207 0.98
183_Q 186_Q 1.205 0.98
41_A 45_V 1.199 0.98
249_I 253_L 1.193 0.98
221_T 296_R 1.187 0.98
225_Q 288_V 1.187 0.98
180_R 183_Q 1.181 0.98
291_L 294_V 1.18 0.98
37_G 301_R 1.175 0.98
240_Y 243_L 1.173 0.98
306_L 334_L 1.172 0.98
280_V 284_W 1.172 0.98
45_V 177_L 1.169 0.97
292_D 296_R 1.167 0.97
150_T 153_F 1.165 0.97
210_A 335_A 1.161 0.97
232_G 236_S 1.161 0.97
318_G 333_L 1.16 0.97
193_T 196_A 1.154 0.97
192_A 200_G 1.153 0.97
225_Q 258_P 1.153 0.97
318_G 334_L 1.153 0.97
225_Q 229_G 1.147 0.97
230_G 242_T 1.14 0.97
53_L 57_K 1.137 0.97
262_L 285_S 1.134 0.97
181_G 185_A 1.132 0.97
86_V 90_V 1.129 0.97
219_V 223_L 1.128 0.97
48_T 74_L 1.127 0.97
218_V 296_R 1.124 0.97
206_L 343_A 1.117 0.96
261_V 331_P 1.113 0.96
112_W 115_T 1.104 0.96
163_F 167_C 1.102 0.96
258_P 261_V 1.101 0.96
65_L 68_L 1.088 0.96
173_F 313_S 1.086 0.96
37_G 41_A 1.082 0.96
275_T 279_T 1.078 0.95
315_V 320_I 1.076 0.95
221_T 225_Q 1.071 0.95
275_T 278_G 1.065 0.95
30_I 33_P 1.057 0.95
252_C 296_R 1.056 0.95
221_T 300_I 1.047 0.94
282_L 286_G 1.04 0.94
269_L 278_G 1.037 0.94
48_T 70_M 1.035 0.94
310_L 334_L 1.034 0.94
221_T 299_L 1.034 0.94
45_V 174_S 1.033 0.94
314_G 318_G 1.032 0.94
318_G 322_F 1.031 0.94
213_A 217_G 1.028 0.94
330_G 334_L 1.026 0.94
262_L 266_I 1.021 0.93
49_W 181_G 1.021 0.93
111_A 114_N 1.021 0.93
68_L 72_L 1.019 0.93
94_G 98_K 1.015 0.93
157_A 161_G 1.007 0.93
67_V 71_T 1.005 0.93
222_A 225_Q 1.004 0.93
278_G 282_L 1.004 0.93
83_A 87_N 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4b19A10.081110.10.966Contact Map0.235
2kv5A10.08928.70.967Contact Map0
2gfpA20.513550.97Contact Map0.164
1ji6A10.19464.10.971Contact Map0.815
2lw9A20.05413.20.973Contact Map
3zjzA40.28923.20.973Contact Map0.431
2l16A10.178430.973Contact Map0.226
3mktA20.95142.80.974Contact Map0.146
2kncA10.13782.60.974Contact Map0.234
3bz1X10.13512.50.974Contact Map0.293
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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