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OPENSEQ.org
YHHT - UPF0118 inner membrane protein YhhT
UniProt: P0AGM0 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12220
Length: 349 (320)
Sequences: 4796
Seq/Len: 14.99
YHHT
Paralog alert: 0.78 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: PERM TQSA YDIK YHHT
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
214_G 267_L 4.677 1.00
212_W 227_A 4.307 1.00
53_W 57_R 3.638 1.00
262_I 266_A 2.796 1.00
55_I 61_R 2.631 1.00
159_V 163_F 2.538 1.00
208_G 227_A 2.51 1.00
208_G 231_F 2.496 1.00
60_Q 63_V 2.491 1.00
45_I 190_L 2.487 1.00
298_S 318_T 2.483 1.00
212_W 216_E 2.47 1.00
59_V 67_I 2.305 1.00
215_L 220_V 2.234 1.00
213_L 216_E 2.185 1.00
53_W 56_R 2.138 1.00
322_K 326_E 2.134 1.00
249_M 265_G 2.123 1.00
259_Y 263_L 2.049 1.00
266_A 270_V 1.993 1.00
43_F 158_V 1.992 1.00
201_T 235_Y 1.958 1.00
157_T 161_M 1.93 1.00
249_M 261_C 1.904 1.00
199_L 283_M 1.841 1.00
216_E 223_A 1.835 1.00
123_R 126_Q 1.821 1.00
211_V 271_V 1.816 1.00
282_R 286_H 1.8 1.00
211_V 230_A 1.797 1.00
40_A 158_V 1.791 1.00
263_L 266_A 1.77 1.00
279_L 283_M 1.702 1.00
93_M 96_K 1.683 1.00
62_P 66_T 1.65 1.00
260_E 263_L 1.648 1.00
48_N 61_R 1.623 1.00
203_L 275_I 1.615 1.00
164_E 291_S 1.605 1.00
157_T 293_M 1.603 1.00
207_T 234_N 1.6 1.00
259_Y 262_I 1.589 1.00
51_V 68_V 1.581 1.00
272_H 276_G 1.578 1.00
303_G 311_M 1.563 1.00
48_N 52_T 1.561 1.00
51_V 65_I 1.547 1.00
229_L 233_L 1.547 1.00
210_I 271_V 1.539 1.00
65_I 159_V 1.538 1.00
47_L 162_L 1.519 1.00
223_A 227_A 1.507 1.00
212_W 223_A 1.501 1.00
99_K 102_T 1.483 1.00
62_P 163_F 1.472 1.00
37_L 297_L 1.468 1.00
213_L 217_L 1.456 1.00
51_V 61_R 1.439 1.00
140_L 144_L 1.406 0.99
233_L 244_S 1.399 0.99
269_L 273_M 1.395 0.99
218_M 267_L 1.383 0.99
41_L 161_M 1.381 0.99
50_L 53_W 1.376 0.99
252_V 261_C 1.345 0.99
164_E 167_H 1.339 0.99
102_T 106_F 1.331 0.99
229_L 244_S 1.327 0.99
189_A 320_V 1.325 0.99
226_W 248_P 1.317 0.99
257_G 260_E 1.304 0.99
154_L 158_V 1.3 0.99
147_A 151_V 1.298 0.99
252_V 264_V 1.295 0.99
59_V 64_A 1.294 0.99
276_G 280_E 1.293 0.99
227_A 231_F 1.289 0.99
120_S 123_R 1.286 0.99
95_P 99_K 1.281 0.99
204_S 234_N 1.263 0.99
50_L 68_V 1.263 0.99
40_A 154_L 1.259 0.99
290_M 318_T 1.254 0.99
309_V 313_L 1.251 0.99
214_G 218_M 1.25 0.99
299_L 311_M 1.232 0.98
100_E 103_R 1.229 0.98
96_K 99_K 1.227 0.98
36_Q 285_G 1.221 0.98
36_Q 40_A 1.214 0.98
274_V 278_I 1.196 0.98
40_A 44_A 1.195 0.98
97_F 101_L 1.186 0.98
208_G 212_W 1.184 0.98
54_F 71_V 1.182 0.98
297_L 301_I 1.182 0.98
47_L 72_M 1.18 0.98
55_I 64_A 1.18 0.98
214_G 271_V 1.176 0.98
203_L 234_N 1.163 0.97
207_T 280_E 1.162 0.97
231_F 235_Y 1.155 0.97
207_T 271_V 1.155 0.97
176_L 179_P 1.151 0.97
201_T 205_L 1.145 0.97
165_V 169_P 1.14 0.97
188_R 327_T 1.14 0.97
291_S 322_K 1.139 0.97
215_L 226_W 1.138 0.97
245_A 249_M 1.135 0.97
104_K 107_K 1.134 0.97
65_I 69_V 1.133 0.97
234_N 241_A 1.129 0.97
73_L 77_T 1.128 0.97
275_I 280_E 1.127 0.97
218_M 264_V 1.127 0.97
203_L 280_E 1.126 0.97
273_M 277_N 1.118 0.96
122_E 125_L 1.118 0.96
37_L 157_T 1.117 0.96
302_W 318_T 1.116 0.96
258_V 261_C 1.115 0.96
170_Y 174_F 1.112 0.96
207_T 211_V 1.109 0.96
226_W 251_Q 1.103 0.96
212_W 224_L 1.102 0.96
263_L 267_L 1.095 0.96
195_H 199_L 1.087 0.96
207_T 241_A 1.083 0.96
253_L 261_C 1.083 0.96
167_H 170_Y 1.081 0.95
248_P 264_V 1.078 0.95
302_W 317_L 1.077 0.95
245_A 268_F 1.074 0.95
88_N 92_S 1.071 0.95
215_L 264_V 1.071 0.95
184_A 327_T 1.07 0.95
222_F 225_M 1.069 0.95
227_A 230_A 1.067 0.95
52_T 56_R 1.064 0.95
200_K 280_E 1.063 0.95
208_G 228_V 1.057 0.95
256_N 260_E 1.054 0.95
91_I 95_P 1.051 0.94
185_G 189_A 1.049 0.94
214_G 263_L 1.049 0.94
159_V 164_E 1.048 0.94
51_V 162_L 1.045 0.94
218_M 260_E 1.044 0.94
61_R 166_R 1.043 0.94
302_W 306_L 1.036 0.94
47_L 68_V 1.036 0.94
33_I 301_I 1.035 0.94
51_V 64_A 1.034 0.94
122_E 126_Q 1.034 0.94
298_S 302_W 1.029 0.94
270_V 274_V 1.027 0.94
258_V 262_I 1.023 0.93
195_H 287_R 1.015 0.93
203_L 207_T 1.006 0.93
17_L 20_L 1.006 0.93
170_Y 183_I 1.004 0.93
89_E 92_S 1 0.92
26_G 30_A 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3b4rA20.20924.90.968Contact Map0.259
1y0hA20.10893.30.97Contact Map0
2rilA10.10893.20.971Contact Map0
3w4tA10.97422.70.972Contact Map0.19
3bo0B10.18622.30.973Contact Map0.203
3ci9A20.12612.30.973Contact Map0.848
4b19A10.0862.20.973Contact Map0.31
3e8oA20.1492.10.973Contact Map0
2kncB10.16332.10.973Contact Map0.14
2kv5A10.09461.90.974Contact Map0.258
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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