| UniProt: | P0A8N3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10552 | ||
| Length: | 505 (488) | ||
| Sequences: | 4633 | ||
| Seq/Len: | 9.49 |
| SYK1
Paralog alert: 0.90 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: EPMA SYD SYK1 SYK2 SYN |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 125_K | 142_E | 4.804 | 1.00 | |
| 201_R | 296_S | 4.75 | 1.00 | |
| 197_F | 296_S | 4.461 | 1.00 | |
| 97_L | 140_C | 3.929 | 1.00 | |
| 69_A | 125_K | 3.772 | 1.00 | |
| 199_V | 256_F | 3.644 | 1.00 | |
| 67_E | 125_K | 3.622 | 1.00 | |
| 196_Q | 200_N | 3.596 | 1.00 | |
| 123_G | 144_R | 3.295 | 1.00 | |
| 53_F | 66_I | 3.292 | 1.00 | |
| 192_S | 196_Q | 3.243 | 1.00 | |
| 244_L | 255_V | 2.842 | 1.00 | |
| 193_G | 300_T | 2.839 | 1.00 | |
| 193_G | 304_D | 2.782 | 1.00 | |
| 67_E | 141_T | 2.775 | 1.00 | |
| 192_S | 199_V | 2.73 | 1.00 | |
| 186_V | 487_T | 2.683 | 1.00 | |
| 194_I | 278_M | 2.68 | 1.00 | |
| 299_R | 322_K | 2.661 | 1.00 | |
| 210_M | 262_F | 2.658 | 1.00 | |
| 428_S | 473_A | 2.635 | 1.00 | |
| 285_A | 289_D | 2.489 | 1.00 | |
| 51_A | 135_E | 2.48 | 1.00 | |
| 210_M | 259_N | 2.419 | 1.00 | |
| 328_T | 392_E | 2.339 | 1.00 | |
| 97_L | 124_A | 2.303 | 1.00 | |
| 248_V | 472_T | 2.302 | 1.00 | |
| 191_L | 479_I | 2.277 | 1.00 | |
| 331_E | 335_K | 2.261 | 1.00 | |
| 328_T | 331_E | 2.256 | 1.00 | |
| 418_I | 423_I | 2.252 | 1.00 | |
| 46_S | 92_G | 2.199 | 1.00 | |
| 295_E | 326_K | 2.174 | 1.00 | |
| 353_A | 356_E | 2.164 | 1.00 | |
| 195_R | 205_E | 2.148 | 1.00 | |
| 392_E | 404_N | 2.097 | 1.00 | |
| 197_F | 201_R | 2.095 | 1.00 | |
| 95_I | 138_I | 2.046 | 1.00 | |
| 327_L | 390_I | 2.032 | 1.00 | |
| 68_V | 138_I | 2.011 | 1.00 | |
| 287_Y | 412_D | 2.01 | 1.00 | |
| 196_Q | 199_V | 2.009 | 1.00 | |
| 190_I | 483_V | 2.008 | 1.00 | |
| 282_M | 285_A | 1.985 | 1.00 | |
| 310_E | 317_T | 1.979 | 1.00 | |
| 290_L | 473_A | 1.972 | 1.00 | |
| 71_A | 123_G | 1.964 | 1.00 | |
| 127_K | 141_T | 1.948 | 1.00 | |
| 197_F | 297_L | 1.936 | 1.00 | |
| 151_R | 466_E | 1.934 | 1.00 | |
| 116_W | 122_L | 1.924 | 1.00 | |
| 292_E | 296_S | 1.917 | 1.00 | |
| 188_S | 199_V | 1.914 | 1.00 | |
| 292_E | 326_K | 1.912 | 1.00 | |
| 67_E | 127_K | 1.911 | 1.00 | |
| 193_G | 301_L | 1.897 | 1.00 | |
| 288_K | 292_E | 1.87 | 1.00 | |
| 224_I | 233_D | 1.857 | 1.00 | |
| 442_D | 445_A | 1.856 | 1.00 | |
| 288_K | 326_K | 1.856 | 1.00 | |
| 196_Q | 304_D | 1.851 | 1.00 | |
| 286_D | 289_D | 1.847 | 1.00 | |
| 27_A | 31_E | 1.845 | 1.00 | |
| 300_T | 304_D | 1.814 | 1.00 | |
| 450_G | 453_E | 1.797 | 1.00 | |
| 197_F | 300_T | 1.792 | 1.00 | |
| 28_N | 31_E | 1.785 | 1.00 | |
| 298_F | 416_F | 1.783 | 1.00 | |
| 291_I | 326_K | 1.751 | 1.00 | |
| 70_V | 95_I | 1.749 | 1.00 | |
| 183_T | 489_S | 1.747 | 1.00 | |
| 437_A | 441_L | 1.734 | 1.00 | |
| 202_G | 254_R | 1.731 | 1.00 | |
| 182_N | 186_V | 1.731 | 1.00 | |
| 129_F | 139_H | 1.727 | 1.00 | |
| 280_L | 475_L | 1.704 | 1.00 | |
| 331_E | 334_K | 1.698 | 1.00 | |
| 194_I | 297_L | 1.694 | 1.00 | |
| 45_T | 48_Q | 1.681 | 1.00 | |
| 185_K | 204_M | 1.672 | 1.00 | |
| 438_Q | 442_D | 1.651 | 1.00 | |
| 310_E | 319_D | 1.651 | 1.00 | |
| 373_T | 377_E | 1.649 | 1.00 | |
| 355_A | 371_I | 1.637 | 1.00 | |
| 437_A | 459_E | 1.634 | 1.00 | |
| 124_A | 140_C | 1.633 | 1.00 | |
| 438_Q | 441_L | 1.632 | 1.00 | |
| 325_E | 386_Q | 1.628 | 1.00 | |
| 353_A | 357_S | 1.622 | 1.00 | |
| 65_N | 127_K | 1.612 | 1.00 | |
| 389_F | 416_F | 1.607 | 1.00 | |
| 451_D | 454_A | 1.606 | 1.00 | |
| 200_N | 300_T | 1.606 | 1.00 | |
| 325_E | 335_K | 1.598 | 1.00 | |
| 332_A | 390_I | 1.575 | 1.00 | |
| 433_A | 437_A | 1.573 | 1.00 | |
| 404_N | 412_D | 1.571 | 1.00 | |
| 455_M | 463_T | 1.57 | 1.00 | |
| 330_R | 334_K | 1.562 | 1.00 | |
| 189_Q | 192_S | 1.556 | 1.00 | |
| 203_F | 282_M | 1.552 | 1.00 | |
| 40_F | 123_G | 1.548 | 1.00 | |
| 50_H | 53_F | 1.53 | 1.00 | |
| 433_A | 466_E | 1.529 | 1.00 | |
| 89_Q | 94_R | 1.525 | 1.00 | |
| 302_A | 486_F | 1.522 | 1.00 | |
| 74_M | 122_L | 1.514 | 1.00 | |
| 140_C | 143_L | 1.504 | 1.00 | |
| 303_Q | 319_D | 1.492 | 1.00 | |
| 327_L | 332_A | 1.483 | 1.00 | |
| 198_M | 278_M | 1.482 | 1.00 | |
| 45_T | 92_G | 1.474 | 1.00 | |
| 374_E | 378_E | 1.474 | 1.00 | |
| 181_R | 185_K | 1.457 | 1.00 | |
| 166_R | 173_D | 1.45 | 1.00 | |
| 330_R | 410_I | 1.449 | 1.00 | |
| 184_F | 497_L | 1.424 | 0.99 | |
| 69_A | 123_G | 1.42 | 0.99 | |
| 194_I | 479_I | 1.414 | 0.99 | |
| 336_Y | 383_H | 1.407 | 0.99 | |
| 285_A | 473_A | 1.402 | 0.99 | |
| 206_V | 252_F | 1.401 | 0.99 | |
| 84_S | 109_Y | 1.391 | 0.99 | |
| 368_L | 372_V | 1.388 | 0.99 | |
| 47_D | 51_A | 1.382 | 0.99 | |
| 70_V | 88_L | 1.381 | 0.99 | |
| 463_T | 504_V | 1.38 | 0.99 | |
| 88_L | 122_L | 1.376 | 0.99 | |
| 178_D | 182_N | 1.376 | 0.99 | |
| 205_E | 256_F | 1.374 | 0.99 | |
| 405_D | 412_D | 1.373 | 0.99 | |
| 74_M | 86_V | 1.364 | 0.99 | |
| 428_S | 431_N | 1.358 | 0.99 | |
| 312_T | 315_D | 1.357 | 0.99 | |
| 185_K | 189_Q | 1.355 | 0.99 | |
| 57_E | 60_E | 1.353 | 0.99 | |
| 437_A | 462_V | 1.353 | 0.99 | |
| 299_R | 321_G | 1.339 | 0.99 | |
| 74_M | 116_W | 1.331 | 0.99 | |
| 261_N | 277_M | 1.331 | 0.99 | |
| 333_I | 372_V | 1.329 | 0.99 | |
| 127_K | 139_H | 1.327 | 0.99 | |
| 348_F | 352_K | 1.32 | 0.99 | |
| 432_D | 435_D | 1.317 | 0.99 | |
| 451_D | 455_M | 1.314 | 0.99 | |
| 240_P | 261_N | 1.308 | 0.99 | |
| 128_L | 136_L | 1.306 | 0.99 | |
| 395_A | 439_R | 1.294 | 0.99 | |
| 87_T | 94_R | 1.293 | 0.99 | |
| 416_F | 424_G | 1.285 | 0.99 | |
| 278_M | 479_I | 1.276 | 0.99 | |
| 190_I | 301_L | 1.273 | 0.99 | |
| 435_D | 438_Q | 1.273 | 0.99 | |
| 328_T | 391_T | 1.268 | 0.99 | |
| 324_F | 416_F | 1.268 | 0.99 | |
| 206_V | 247_L | 1.266 | 0.99 | |
| 254_R | 282_M | 1.263 | 0.98 | |
| 403_R | 432_D | 1.263 | 0.98 | |
| 403_R | 435_D | 1.262 | 0.98 | |
| 381_E | 384_L | 1.26 | 0.98 | |
| 182_N | 185_K | 1.259 | 0.98 | |
| 295_E | 323_P | 1.257 | 0.98 | |
| 303_Q | 307_G | 1.245 | 0.98 | |
| 184_F | 252_F | 1.237 | 0.98 | |
| 20_K | 24_E | 1.233 | 0.98 | |
| 194_I | 301_L | 1.228 | 0.98 | |
| 186_V | 305_I | 1.226 | 0.98 | |
| 211_M | 234_M | 1.218 | 0.98 | |
| 334_K | 338_P | 1.214 | 0.98 | |
| 309_T | 321_G | 1.206 | 0.98 | |
| 64_L | 130_K | 1.204 | 0.98 | |
| 282_M | 293_L | 1.203 | 0.98 | |
| 347_N | 350_S | 1.201 | 0.98 | |
| 198_M | 280_L | 1.2 | 0.98 | |
| 441_L | 451_D | 1.182 | 0.97 | |
| 169_Q | 463_T | 1.181 | 0.97 | |
| 349_D | 352_K | 1.179 | 0.97 | |
| 189_Q | 304_D | 1.176 | 0.97 | |
| 350_S | 353_A | 1.175 | 0.97 | |
| 395_A | 403_R | 1.172 | 0.97 | |
| 242_L | 460_D | 1.163 | 0.97 | |
| 198_M | 297_L | 1.163 | 0.97 | |
| 335_K | 341_D | 1.161 | 0.97 | |
| 295_E | 324_F | 1.16 | 0.97 | |
| 193_G | 305_I | 1.159 | 0.97 | |
| 49_L | 53_F | 1.157 | 0.97 | |
| 189_Q | 199_V | 1.155 | 0.97 | |
| 190_I | 486_F | 1.153 | 0.97 | |
| 285_A | 290_L | 1.151 | 0.97 | |
| 315_D | 488_N | 1.148 | 0.97 | |
| 92_G | 253_E | 1.144 | 0.97 | |
| 111_E | 114_K | 1.138 | 0.97 | |
| 232_L | 503_P | 1.136 | 0.97 | |
| 338_P | 369_G | 1.135 | 0.96 | |
| 193_G | 196_Q | 1.133 | 0.96 | |
| 296_S | 299_R | 1.131 | 0.96 | |
| 174_L | 184_F | 1.129 | 0.96 | |
| 86_V | 122_L | 1.127 | 0.96 | |
| 90_D | 93_G | 1.118 | 0.96 | |
| 401_A | 427_F | 1.117 | 0.96 | |
| 128_L | 138_I | 1.113 | 0.96 | |
| 179_E | 489_S | 1.108 | 0.96 | |
| 226_H | 233_D | 1.104 | 0.96 | |
| 294_T | 477_I | 1.103 | 0.96 | |
| 226_H | 231_D | 1.1 | 0.96 | |
| 240_P | 277_M | 1.1 | 0.96 | |
| 437_A | 466_E | 1.093 | 0.95 | |
| 106_E | 111_E | 1.093 | 0.95 | |
| 44_H | 48_Q | 1.088 | 0.95 | |
| 354_I | 358_I | 1.087 | 0.95 | |
| 70_V | 138_I | 1.083 | 0.95 | |
| 45_T | 253_E | 1.08 | 0.95 | |
| 99_V | 140_C | 1.077 | 0.95 | |
| 228_N | 231_D | 1.067 | 0.95 | |
| 188_S | 192_S | 1.065 | 0.94 | |
| 27_A | 30_R | 1.054 | 0.94 | |
| 99_V | 143_L | 1.051 | 0.94 | |
| 24_E | 28_N | 1.049 | 0.94 | |
| 113_F | 143_L | 1.036 | 0.93 | |
| 83_A | 98_Y | 1.036 | 0.93 | |
| 181_R | 252_F | 1.034 | 0.93 | |
| 188_S | 256_F | 1.033 | 0.93 | |
| 24_E | 27_A | 1.028 | 0.93 | |
| 190_I | 479_I | 1.027 | 0.93 | |
| 212_Q | 243_Y | 1.024 | 0.93 | |
| 463_T | 466_E | 1.022 | 0.93 | |
| 207_E | 260_R | 1.019 | 0.93 | |
| 44_H | 53_F | 1.017 | 0.92 | |
| 224_I | 235_Y | 1.017 | 0.92 | |
| 301_L | 305_I | 1.015 | 0.92 | |
| 123_G | 146_L | 1.014 | 0.92 | |
| 240_P | 243_Y | 1.014 | 0.92 | |
| 186_V | 190_I | 1.014 | 0.92 | |
| 191_L | 278_M | 1.006 | 0.92 | |
| 203_F | 254_R | 1.005 | 0.92 | |
| 402_R | 431_N | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4ex5A | 2 | 0.998 | 100 | 0.042 | Contact Map | 0.712 |
| 4h02A | 8 | 0.9723 | 100 | 0.088 | Contact Map | 0.809 |
| 1e1oA | 1 | 0.998 | 100 | 0.095 | Contact Map | 0.687 |
| 3bjuA | 4 | 0.9762 | 100 | 0.096 | Contact Map | 0.775 |
| 3a74A | 4 | 0.9743 | 100 | 0.108 | Contact Map | 0.808 |
| 1l0wA | 2 | 0.8574 | 100 | 0.223 | Contact Map | 0.791 |
| 4ah6A | 4 | 0.8653 | 100 | 0.224 | Contact Map | 0.684 |
| 1c0aA | 1 | 0.8574 | 100 | 0.232 | Contact Map | 0.719 |
| 4j15A | 2 | 0.9149 | 100 | 0.244 | Contact Map | 0.69 |
| 3i7fA | 2 | 0.9069 | 100 | 0.248 | Contact Map | 0.7 |
Sequence Conservation (Image Generated using WebLogo v3)