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OPENSEQ.org

GCST - MTOX
UniProt: P27248 - P40874
Length: 736
Sequences: 646
Seq/Len: 0.89
I_Prob: 0.00

GCST - Aminomethyltransferase
Paralog alert: 0.58 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: GCST YGFZ
MTOX - N-methyl-L-tryptophan oxidase
Paralog alert: 0.81 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: DADA LHGO MTOX PUUB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2gagA:B:C:A:CContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
133_G 90_I 1.25 0.00
255_I 7_I 1.13 0.00
18_M 137_G 1.10 0.00
57_L 192_Q 1.06 0.00
291_V 137_G 0.98 0.00
303_A 2_K 0.97 0.00
67_R 7_I 0.96 0.00
155_K 283_S 0.96 0.00
322_G 192_Q 0.96 0.00
152_A 90_I 0.95 0.00
14_C 137_G 0.95 0.00
30_Y 161_E 0.95 0.00
13_L 90_I 0.94 0.00
105_T 193_A 0.94 0.00
147_V 331_L 0.93 0.00
194_G 114_V 0.92 0.00
107_D 92_L 0.92 0.00
27_P 135_Y 0.92 0.00
330_V 356_D 0.92 0.00
152_A 131_V 0.92 0.00
139_R 208_L 0.91 0.00
152_A 356_D 0.91 0.00
104_F 137_G 0.91 0.00
82_K 137_G 0.90 0.00
305_G 130_R 0.88 0.00
46_M 23_R 0.88 0.00
9_E 192_Q 0.88 0.00
338_A 173_T 0.87 0.00
349_V 110_W 0.87 0.00
30_Y 221_A 0.86 0.00
197_I 299_I 0.86 0.00
30_Y 181_G 0.85 0.00
151_N 328_N 0.85 0.00
321_L 137_G 0.84 0.00
129_A 354_A 0.84 0.00
105_T 74_L 0.84 0.00
152_A 207_L 0.83 0.00
334_I 124_A 0.83 0.00
250_N 118_D 0.83 0.00
197_I 8_I 0.83 0.00
17_R 204_V 0.83 0.00
348_P 121_G 0.83 0.00
125_I 113_N 0.82 0.00
140_D 303_L 0.82 0.00
333_G 28_V 0.81 0.00
33_Q 144_G 0.81 0.00
147_V 90_I 0.81 0.00
299_R 31_T 0.80 0.00
190_T 348_E 0.80 0.00
95_V 175_I 0.80 0.00
314_S 258_L 0.80 0.00
328_A 134_N 0.80 0.00
152_A 197_I 0.79 0.00
71_A 221_A 0.79 0.00
303_A 8_I 0.79 0.00
197_I 197_I 0.79 0.00
213_E 207_L 0.78 0.00
204_A 10_S 0.78 0.00
64_E 177_H 0.77 0.00
57_L 184_I 0.77 0.00
211_L 354_A 0.77 0.00
44_A 10_S 0.77 0.00
160_F 208_L 0.77 0.00
137_T 28_V 0.77 0.00
246_P 336_S 0.77 0.00
107_D 172_V 0.77 0.00
30_Y 326_H 0.77 0.00
23_G 121_G 0.77 0.00
354_P 354_A 0.77 0.00
207_F 143_S 0.76 0.00
120_K 328_N 0.76 0.00
255_I 124_A 0.76 0.00
155_K 177_H 0.76 0.00
328_A 17_A 0.76 0.00
158_T 8_I 0.76 0.00
333_G 6_I 0.76 0.00
289_K 31_T 0.76 0.00
69_L 188_D 0.76 0.00
106_E 32_D 0.76 0.00
351_V 199_C 0.75 0.00
145_I 197_I 0.75 0.00
349_V 119_A 0.75 0.00
265_I 328_N 0.75 0.00
252_G 5_L 0.75 0.00
289_K 192_Q 0.75 0.00
104_F 320_I 0.75 0.00
340_V 358_K 0.75 0.00
328_A 236_P 0.75 0.00
13_L 165_A 0.75 0.00
322_G 285_G 0.74 0.00
328_A 194_K 0.74 0.00
101_V 6_I 0.74 0.00
239_E 90_I 0.74 0.00
57_L 179_D 0.74 0.00
352_T 182_V 0.74 0.00
184_I 162_A 0.74 0.00
301_T 367_R 0.73 0.00
354_P 118_D 0.73 0.00
147_V 7_I 0.73 0.00
209_R 196_A 0.73 0.00
269_A 320_I 0.73 0.00
6_P 112_L 0.73 0.00
324_S 204_V 0.73 0.00
44_A 111_Q 0.73 0.00
39_A 196_A 0.72 0.00
240_M 336_S 0.72 0.00
356_F 143_S 0.72 0.00
105_T 67_A 0.72 0.00
102_Y 313_S 0.72 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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