OPENSEQ.org -1516281329- GREMLIN Submission

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mep50

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Coupling matrix for [T:0304] and [L:0313]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.9	0.4	0.1	0.2	0.6	-0.4	0.5	0.3	-0.2	-0.4	-0.4	-0.3	0.5	-0.6	-1	0.2	0.2	0.1	-0.1	0.1
F	-0.6	-0.3	-0.4	0.2	-0.1	0.1	-0.1	0.8	0.2	0	0	-0.1	-0.1	0	-0.1	-0.3	0.1	0.2	0	-0.1
I	0.1	0.2	0.4	0.1	-0.1	-0.4	-0.1	-0.2	-0.1	0	-0.1	-0.1	0.1	-0.1	0.1	0.1	0.3	-0.2	0.2	0
L	-0.7	0.2	0.2	0.4	0.2	0.4	0	-0.4	0.2	-0.1	-0.1	-0.1	0	0.1	0	-0.6	0.2	-0.4	0.1	-0.1
V	0.6	0.4	0.1	0.4	0.1	-0.2	-0.1	0.2	0.1	-0.1	0.1	-0.4	-0.1	0	0.1	0	0.4	-1	0	-0.4
M	-0.7	0.3	0.2	0.3	0	0.4	-0.1	-0.3	0	0	0	-0.1	-0.1	0	-0.1	0.1	-0.2	-0.3	0	0.2
W	-0.4	0	-0.1	-0.1	-0.4	0.1	0	-0.1	0	0	0	0	0	0	0	-0.1	-0.1	-0.1	0	-0.1
Y	-0.5	0.1	0.6	0.1	-0.4	0.4	-0.1	0.2	0	0	0	-0.1	0.2	0	-0.1	-0.2	-0.1	-0.2	0	-0.2
D	-0.2	-1	-0.5	-0.9	0	-0.1	0.4	-0.1	-0.2	-0.2	-0.1	1.8	0.1	-0.1	2.1	0	-0.3	-0.2	-0.1	0.6
E	0.1	-0.1	0.2	0.5	0.1	0.1	0.7	-0.5	-0.1	-0.1	-0.1	0	-0.2	0.1	-0.3	-0.2	-0.2	0.2	-0.1	-0.1
K	0.4	0.3	0.1	0	0.2	0.4	-0.1	0	-0.1	-0.1	-0.2	-0.4	-0.2	-0.2	-0.3	0.6	-0.1	-0.1	0	-0.1
R	0.1	0.3	0.1	0	0.3	0.1	-0.3	0.3	0.1	0.4	-0.2	-0.2	0.2	-0.2	-0.4	0.1	0.1	0.7	0	-0.4
H	-0.3	0.1	-0.3	0.4	0.1	0.5	-0.1	0.2	-0.1	0	-0.1	-0.2	-0.1	-0.1	-0.2	-0.2	-0.1	0.1	-0.1	0.6
N	0.1	0.1	0.1	-0.4	-0.1	-0.1	-0.1	-0.1	0	0	-0.1	-0.1	-0.1	0.4	0.1	0	0.1	0.1	0	0.2
Q	-0.2	0	0.2	0.3	0.6	-0.2	-0.3	-0.2	-0.1	-0.1	1	-0.4	-0.2	0.1	-0.3	-0.5	-0.3	0.6	-0.1	0
S	0.9	0	0	0.1	0.3	0.2	-0.1	0.3	-0.3	-0.2	-0.3	-0.4	-0.4	-0.2	0	0.2	0.6	0.3	-0.2	0
T	0.6	0.1	0.4	0.4	0.2	0.2	-0.3	0.2	0.1	-0.1	0	-0.5	-0.4	0.1	-0.4	0.1	0.1	-0.4	-0.2	0.5
G	0.1	0	-0.2	-0.5	0.2	-0.4	0	0.3	-0.1	-0.1	-0.1	0.9	0	0.3	0.1	-0.4	-0.2	0.6	-0.1	-0.4
P	-0.2	0.2	-0.1	0.2	-0.6	-0.1	0	0	0	0	0	0.1	0.2	0	0	0.4	-0.1	-0.1	0	-0.1
C	0.3	0.4	0.4	0.6	0.3	-0.1	-0.1	-0.6	-0.1	-0.1	-0.1	-0.4	0.1	-0.1	-0.2	0.4	-0.3	-0.2	-0.1	0.1

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0304	1.4	-0.7	0.4	0	1	-0.6	-1.5	-0.5	0.4	0.1	-0.3	0.7	-0.2	-0.2	0	1	0.7	0	-1.2	0.4
0313	0.8	1.6	2.2	2.8	2.1	0.6	-0.9	0.4	-1.4	-1.7	-1.2	-1.3	-0.8	-1	-1.7	-0.1	0.1	-0.6	-1.3	0.1

Select residue pair below:

i_j	Score	Prob
0313_0324	1.122	0.97
0036_0313	0.640	0.50
0304_0313	0.578	0.40

Local Interactions:

i_j	Score	Prob
0313_0314	1.235	0.98
0312_0313	0.878	0.84
0311_0313	0.780	0.73

See all coupling residues
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