OPENSEQ.org -1516281329- GREMLIN Submission

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mep50

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Coupling matrix for [L:0218] and [W:0220]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	-0.1	1.3	0	-0.1	-0.2	-0.1	1.2	0.7	-0.1	-0.1	-0.1	-0.7	0.2	-0.1	-0.2	-0.5	0	0	0.1	-0.4
F	0	-0.5	-0.1	-0.2	0.3	-0.1	-0.8	0.4	0.8	0.6	0.3	-0.2	0	0.3	-0.3	0	0.3	0.1	0	-0.2
I	0.4	-0.4	0.2	0	0.3	0.3	-0.2	0	-0.4	-0.4	-0.1	-0.1	0.1	-0.2	-0.3	0.7	0.6	0	0.6	0.3
L	0.4	-0.2	0.1	0.1	0.7	0	-0.1	0.1	-0.3	-0.2	0	0.7	-0.1	-0.1	0.1	0	0.5	-0.1	-0.3	0.3
V	0.4	0.3	0.2	0	0.5	0.3	0.1	0.6	-0.7	-0.3	-0.5	0	-0.2	-0.5	-0.4	0.2	0.1	0.1	0.1	0.5
M	-0.2	-0.2	0.5	0.4	0.2	0.4	-0.6	0.7	-0.4	-0.1	0	-0.1	-0.2	0.3	0.1	0	-0.2	0.4	0	-0.1
W	-0.1	-0.4	-0.3	-0.1	-0.3	0.3	0.6	-0.2	0	0	0	0	0.2	0	0	-0.1	-0.1	0	-0.1	-0.1
Y	0.1	-0.2	-0.4	0.3	0.1	0.1	-0.4	-0.3	0.5	0.1	0	0	-0.1	0	0	-0.1	0.1	-0.1	-0.1	-0.1
D	-0.1	0	0.1	0.2	0	-0.1	-0.3	-0.2	0	0	0	0	0.2	0	0	-0.1	-0.1	0	0	0.2
E	0.1	0	-0.3	0	-0.1	-0.1	-0.8	-0.3	0	0	0	-0.1	0.5	0	0	-0.1	-0.1	0.2	-0.1	0.2
K	0.4	-0.4	0	0.1	-0.2	-0.1	-0.3	-0.1	0	0	0	0	0	0	0	0.2	-0.1	0	0	0
R	0.1	-0.3	-0.3	0	-0.1	-0.2	-0.4	-0.2	0	0	0	-0.1	-0.1	0	0.2	-0.1	0.1	0.2	-0.1	0.6
H	0.1	-0.6	-0.1	-0.2	0.2	-0.1	-0.2	-0.1	0	0	0	0	0.2	0	0	0.4	-0.1	-0.1	-0.1	0.1
N	-0.2	-0.6	-0.2	-0.3	-0.2	-0.2	0.9	-0.1	0	0	-0.1	-0.1	-0.1	0	0	0.1	-0.1	-0.1	0.1	-0.1
Q	-0.1	-0.5	-0.3	-0.5	-0.1	0.3	-0.4	0.1	0.5	0	-0.1	0.3	-0.1	0	0.1	-0.1	0.6	-0.1	0.1	-0.1
S	0.1	0.4	0.1	-0.1	0	-0.2	-0.1	-0.6	0.2	0.1	0.2	-0.1	0	0	0.5	0.5	-0.2	-0.1	0.1	-0.2
T	-0.6	0.5	0.7	0.3	0.3	-0.4	0.4	0.4	-0.1	0.4	-0.2	-0.3	0.1	-0.1	-0.2	-0.5	-0.3	-0.2	-0.1	0.1
G	-0.1	0.6	0.2	0.2	-0.5	0.1	0.3	-0.4	0	0	0	0.1	-0.1	0	0.2	-0.1	-0.1	-0.1	0.1	-0.1
P	0	0.7	0.1	-0.4	-0.5	-0.2	0.7	-0.4	0	0	0.2	0.2	-0.1	0	-0.1	0	-0.2	-0.1	-0.1	0
C	0.1	0.8	0.4	0	0.6	0.3	0.8	0.5	0	-0.2	-0.1	-0.4	-0.4	0.1	0.3	-0.3	-0.4	-0.5	-0.1	-0.8

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0218	0.9	0.9	1.6	1.8	1.2	1.1	-1	-0.6	-0.8	-1.2	-1.1	-0.5	-1	-1.4	-0.6	0.6	0.2	0.5	-0.5	0.1
0220	0.7	0.7	0.4	0.8	0.9	0.2	-0.3	0.1	-0.6	-0.4	-0.6	-0.8	-0.1	-0.6	-0.2	0	0.3	-0.3	0	0

Select residue pair below:

i_j	Score	Prob
0184_0218	1.720	1.00
0186_0218	1.173	0.98
0174_0218	1.009	0.93
0218_0230	0.859	0.82
0172_0218	0.806	0.76
0192_0218	0.673	0.56

Local Interactions:

i_j	Score	Prob
0218_0220	0.756	0.69
0218_0219	0.722	0.64
0216_0218	0.579	0.40

See all coupling residues
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