| UniProt: | P0AG84 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11292 | ||
| Length: | 294 (248) | ||
| Sequences: | 39483 | ||
| Seq/Len: | 159.21 |
| YGHA
Paralog alert: 0.90 [within 20: 0.40] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 154_Q | 162_F | 3.302 | 1.00 | |
| 180_S | 223_R | 2.901 | 1.00 | |
| 154_Q | 158_A | 2.834 | 1.00 | |
| 111_D | 114_F | 2.798 | 1.00 | |
| 204_A | 208_N | 2.715 | 1.00 | |
| 183_T | 210_S | 2.54 | 1.00 | |
| 52_A | 131_I | 2.394 | 1.00 | |
| 228_A | 284_V | 2.375 | 1.00 | |
| 168_T | 213_L | 2.361 | 1.00 | |
| 123_H | 174_L | 2.354 | 1.00 | |
| 63_R | 67_I | 2.288 | 1.00 | |
| 116_R | 170_E | 2.268 | 1.00 | |
| 131_I | 273_A | 2.21 | 1.00 | |
| 233_W | 261_Q | 2.166 | 1.00 | |
| 185_S | 207_L | 2.127 | 1.00 | |
| 134_L | 183_T | 2.097 | 1.00 | |
| 267_P | 276_E | 2.033 | 1.00 | |
| 75_D | 101_K | 2.001 | 1.00 | |
| 119_V | 171_A | 1.997 | 1.00 | |
| 112_E | 150_S | 1.994 | 1.00 | |
| 68_A | 267_P | 1.953 | 1.00 | |
| 268_V | 285_H | 1.949 | 1.00 | |
| 158_A | 162_F | 1.941 | 1.00 | |
| 172_I | 217_V | 1.94 | 1.00 | |
| 283_E | 286_G | 1.903 | 1.00 | |
| 65_A | 269_Y | 1.885 | 1.00 | |
| 68_A | 270_V | 1.879 | 1.00 | |
| 51_K | 75_D | 1.812 | 1.00 | |
| 79_S | 107_G | 1.811 | 1.00 | |
| 160_N | 202_T | 1.785 | 1.00 | |
| 68_A | 72_E | 1.756 | 1.00 | |
| 210_S | 226_I | 1.731 | 1.00 | |
| 176_P | 220_K | 1.724 | 1.00 | |
| 164_L | 206_I | 1.702 | 1.00 | |
| 69_Y | 273_A | 1.683 | 1.00 | |
| 67_I | 94_I | 1.67 | 1.00 | |
| 121_E | 125_A | 1.665 | 1.00 | |
| 260_G | 279_Y | 1.658 | 1.00 | |
| 120_H | 124_K | 1.644 | 1.00 | |
| 63_R | 94_I | 1.621 | 1.00 | |
| 61_I | 232_I | 1.615 | 1.00 | |
| 72_E | 270_V | 1.603 | 1.00 | |
| 63_R | 91_V | 1.584 | 1.00 | |
| 161_V | 205_A | 1.578 | 1.00 | |
| 88_A | 104_L | 1.577 | 1.00 | |
| 77_A | 122_A | 1.572 | 1.00 | |
| 83_V | 89_Q | 1.548 | 1.00 | |
| 58_D | 80_Y | 1.548 | 1.00 | |
| 157_F | 161_V | 1.547 | 1.00 | |
| 117_S | 121_E | 1.544 | 1.00 | |
| 103_V | 125_A | 1.542 | 1.00 | |
| 79_S | 118_L | 1.533 | 1.00 | |
| 74_A | 131_I | 1.514 | 1.00 | |
| 227_V | 269_Y | 1.511 | 1.00 | |
| 107_G | 114_F | 1.508 | 1.00 | |
| 132_M | 167_L | 1.506 | 1.00 | |
| 150_S | 166_W | 1.485 | 1.00 | |
| 149_T | 152_Q | 1.474 | 1.00 | |
| 116_R | 120_H | 1.472 | 1.00 | |
| 51_K | 128_G | 1.469 | 1.00 | |
| 68_A | 71_R | 1.465 | 1.00 | |
| 57_G | 78_I | 1.456 | 1.00 | |
| 121_E | 124_K | 1.454 | 1.00 | |
| 52_A | 69_Y | 1.448 | 1.00 | |
| 77_A | 126_L | 1.405 | 0.99 | |
| 268_V | 287_V | 1.361 | 0.99 | |
| 89_Q | 93_K | 1.36 | 0.99 | |
| 49_D | 74_A | 1.348 | 0.99 | |
| 66_A | 78_I | 1.347 | 0.99 | |
| 115_A | 167_L | 1.341 | 0.99 | |
| 133_A | 184_T | 1.337 | 0.99 | |
| 232_I | 260_G | 1.324 | 0.99 | |
| 213_L | 224_V | 1.315 | 0.99 | |
| 107_G | 118_L | 1.315 | 0.99 | |
| 92_K | 96_E | 1.311 | 0.99 | |
| 129_L | 171_A | 1.307 | 0.99 | |
| 75_D | 100_R | 1.306 | 0.99 | |
| 162_F | 166_W | 1.287 | 0.99 | |
| 114_F | 117_S | 1.287 | 0.99 | |
| 112_E | 166_W | 1.286 | 0.99 | |
| 69_Y | 74_A | 1.262 | 0.99 | |
| 47_L | 74_A | 1.256 | 0.99 | |
| 185_S | 226_I | 1.255 | 0.99 | |
| 59_S | 235_A | 1.25 | 0.99 | |
| 150_S | 162_F | 1.25 | 0.99 | |
| 168_T | 181_I | 1.223 | 0.98 | |
| 93_K | 96_E | 1.213 | 0.98 | |
| 112_E | 116_R | 1.21 | 0.98 | |
| 105_L | 121_E | 1.207 | 0.98 | |
| 190_Y | 286_G | 1.204 | 0.98 | |
| 85_E | 89_Q | 1.197 | 0.98 | |
| 93_K | 97_E | 1.189 | 0.98 | |
| 134_L | 168_T | 1.188 | 0.98 | |
| 153_F | 162_F | 1.178 | 0.98 | |
| 67_I | 71_R | 1.178 | 0.98 | |
| 132_M | 171_A | 1.172 | 0.98 | |
| 180_S | 225_N | 1.171 | 0.98 | |
| 258_R | 264_E | 1.162 | 0.97 | |
| 271_Y | 280_V | 1.158 | 0.97 | |
| 103_V | 126_L | 1.146 | 0.97 | |
| 226_I | 284_V | 1.141 | 0.97 | |
| 92_K | 104_L | 1.138 | 0.97 | |
| 52_A | 74_A | 1.134 | 0.97 | |
| 65_A | 133_A | 1.126 | 0.97 | |
| 113_K | 117_S | 1.121 | 0.97 | |
| 138_K | 159_I | 1.114 | 0.96 | |
| 207_L | 284_V | 1.114 | 0.96 | |
| 71_R | 98_C | 1.111 | 0.96 | |
| 109_L | 163_A | 1.105 | 0.96 | |
| 68_A | 266_A | 1.105 | 0.96 | |
| 157_F | 162_F | 1.098 | 0.96 | |
| 210_S | 224_V | 1.096 | 0.96 | |
| 64_A | 263_A | 1.088 | 0.96 | |
| 51_K | 77_A | 1.087 | 0.96 | |
| 82_P | 87_D | 1.081 | 0.95 | |
| 61_I | 65_A | 1.065 | 0.95 | |
| 184_T | 269_Y | 1.056 | 0.95 | |
| 59_S | 87_D | 1.056 | 0.95 | |
| 64_A | 67_I | 1.054 | 0.95 | |
| 53_L | 118_L | 1.046 | 0.94 | |
| 151_E | 155_K | 1.041 | 0.94 | |
| 143_P | 152_Q | 1.04 | 0.94 | |
| 64_A | 262_P | 1.036 | 0.94 | |
| 112_E | 169_Q | 1.025 | 0.93 | |
| 117_S | 120_H | 1.024 | 0.93 | |
| 148_L | 198_D | 1.023 | 0.93 | |
| 199_Y | 203_K | 1.021 | 0.93 | |
| 248_P | 252_Q | 1.017 | 0.93 | |
| 280_V | 285_H | 1.013 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r3sA | 4 | 1 | 100 | 0.234 | Contact Map | 0.827 |
| 4egfA | 8 | 0.8912 | 100 | 0.278 | Contact Map | 0.828 |
| 1vl8A | 2 | 0.8946 | 100 | 0.281 | Contact Map | 0.811 |
| 3v8bA | 4 | 0.9218 | 100 | 0.281 | Contact Map | 0.845 |
| 1zemA | 8 | 0.8367 | 100 | 0.283 | Contact Map | 0.862 |
| 3cxtA | 1 | 0.9354 | 100 | 0.286 | Contact Map | 0.7 |
| 1geeA | 4 | 0.8503 | 100 | 0.286 | Contact Map | 0.853 |
| 4lvuA | 2 | 0.9354 | 100 | 0.286 | Contact Map | 0.744 |
| 4j2hA | 1 | 0.8639 | 100 | 0.286 | Contact Map | 0.756 |
| 4fn4A | 4 | 0.8435 | 100 | 0.287 | Contact Map | 0.935 |
Sequence Conservation (Image Generated using WebLogo v3)