| UniProt: | P0CI31 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13459 | ||
| Length: | 270 (255) | ||
| Sequences: | 44312 | ||
| Seq/Len: | 173.77 |
| HCAB
Paralog alert: 0.89 [within 20: 0.45] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 110_H | 118_L | 3.403 | 1.00 | |
| 110_H | 114_N | 3.026 | 1.00 | |
| 63_C | 66_D | 2.904 | 1.00 | |
| 161_H | 165_G | 2.784 | 1.00 | |
| 137_S | 179_R | 2.719 | 1.00 | |
| 140_F | 167_I | 2.547 | 1.00 | |
| 9_I | 83_C | 2.439 | 1.00 | |
| 75_L | 130_A | 2.414 | 1.00 | |
| 124_A | 170_L | 2.412 | 1.00 | |
| 20_L | 24_E | 2.404 | 1.00 | |
| 184_G | 249_M | 2.347 | 1.00 | |
| 68_Q | 126_A | 2.31 | 1.00 | |
| 142_L | 164_T | 2.226 | 1.00 | |
| 83_C | 237_T | 2.183 | 1.00 | |
| 189_A | 225_Q | 2.168 | 1.00 | |
| 32_Q | 53_H | 2.034 | 1.00 | |
| 71_V | 127_C | 2.032 | 1.00 | |
| 114_N | 118_L | 2.028 | 1.00 | |
| 128_A | 174_L | 2.015 | 1.00 | |
| 86_G | 140_F | 2.014 | 1.00 | |
| 25_R | 231_G | 2.014 | 1.00 | |
| 248_V | 251_N | 1.923 | 1.00 | |
| 64_Y | 106_E | 1.914 | 1.00 | |
| 40_A | 44_A | 1.89 | 1.00 | |
| 8_S | 32_Q | 1.889 | 1.00 | |
| 25_R | 29_E | 1.881 | 1.00 | |
| 36_L | 59_G | 1.879 | 1.00 | |
| 22_L | 233_Y | 1.879 | 1.00 | |
| 25_R | 234_V | 1.878 | 1.00 | |
| 232_P | 250_I | 1.862 | 1.00 | |
| 116_N | 159_S | 1.831 | 1.00 | |
| 120_Y | 163_A | 1.807 | 1.00 | |
| 132_I | 177_K | 1.789 | 1.00 | |
| 167_I | 182_G | 1.788 | 1.00 | |
| 18_L | 188_M | 1.77 | 1.00 | |
| 73_Q | 77_R | 1.729 | 1.00 | |
| 26_F | 237_T | 1.688 | 1.00 | |
| 72_D | 76_T | 1.682 | 1.00 | |
| 14_G | 35_T | 1.639 | 1.00 | |
| 31_A | 83_C | 1.629 | 1.00 | |
| 34_A | 74_I | 1.626 | 1.00 | |
| 15_G | 37_E | 1.621 | 1.00 | |
| 29_E | 234_V | 1.616 | 1.00 | |
| 36_L | 70_A | 1.608 | 1.00 | |
| 224_P | 244_A | 1.602 | 1.00 | |
| 113_F | 117_V | 1.596 | 1.00 | |
| 34_A | 78_S | 1.594 | 1.00 | |
| 55_L | 77_R | 1.591 | 1.00 | |
| 117_V | 162_A | 1.588 | 1.00 | |
| 231_G | 240_R | 1.586 | 1.00 | |
| 69_R | 73_Q | 1.584 | 1.00 | |
| 84_F | 123_G | 1.554 | 1.00 | |
| 8_S | 80_K | 1.546 | 1.00 | |
| 59_G | 66_D | 1.541 | 1.00 | |
| 68_Q | 72_D | 1.539 | 1.00 | |
| 25_R | 28_E | 1.524 | 1.00 | |
| 9_I | 26_F | 1.492 | 1.00 | |
| 73_Q | 76_T | 1.491 | 1.00 | |
| 183_V | 233_Y | 1.482 | 1.00 | |
| 39_S | 42_K | 1.478 | 1.00 | |
| 24_E | 49_R | 1.472 | 1.00 | |
| 43_V | 56_A | 1.455 | 1.00 | |
| 106_E | 122_L | 1.441 | 1.00 | |
| 6_N | 31_A | 1.426 | 1.00 | |
| 32_Q | 52_E | 1.404 | 0.99 | |
| 105_L | 108_G | 1.403 | 0.99 | |
| 64_Y | 122_L | 1.388 | 0.99 | |
| 67_Y | 123_G | 1.382 | 0.99 | |
| 23_V | 35_T | 1.373 | 0.99 | |
| 59_G | 70_A | 1.371 | 0.99 | |
| 232_P | 252_A | 1.358 | 0.99 | |
| 16_S | 191_D | 1.355 | 0.99 | |
| 85_I | 141_T | 1.342 | 0.99 | |
| 20_L | 46_L | 1.34 | 0.99 | |
| 26_F | 31_A | 1.339 | 0.99 | |
| 137_S | 181_N | 1.337 | 0.99 | |
| 170_L | 180_V | 1.329 | 0.99 | |
| 64_Y | 68_Q | 1.319 | 0.99 | |
| 66_D | 69_R | 1.316 | 0.99 | |
| 118_L | 122_L | 1.306 | 0.99 | |
| 44_A | 48_Q | 1.304 | 0.99 | |
| 40_A | 58_E | 1.302 | 0.99 | |
| 188_M | 224_P | 1.299 | 0.99 | |
| 86_G | 124_A | 1.291 | 0.99 | |
| 57_V | 73_Q | 1.289 | 0.99 | |
| 142_L | 182_G | 1.287 | 0.99 | |
| 4_L | 31_A | 1.28 | 0.99 | |
| 9_I | 31_A | 1.261 | 0.99 | |
| 81_L | 127_C | 1.255 | 0.99 | |
| 130_A | 134_S | 1.242 | 0.98 | |
| 124_A | 138_M | 1.226 | 0.98 | |
| 65_A | 69_R | 1.22 | 0.98 | |
| 167_I | 180_V | 1.212 | 0.98 | |
| 222_F | 228_D | 1.211 | 0.98 | |
| 147_W | 251_N | 1.208 | 0.98 | |
| 84_F | 127_C | 1.2 | 0.98 | |
| 55_L | 78_S | 1.196 | 0.98 | |
| 106_E | 118_L | 1.195 | 0.98 | |
| 24_E | 28_E | 1.187 | 0.98 | |
| 235_M | 245_L | 1.183 | 0.98 | |
| 20_L | 49_R | 1.166 | 0.97 | |
| 21_A | 24_E | 1.162 | 0.97 | |
| 109_F | 118_L | 1.146 | 0.97 | |
| 44_A | 47_R | 1.143 | 0.97 | |
| 25_R | 230_T | 1.135 | 0.97 | |
| 22_L | 85_I | 1.131 | 0.97 | |
| 182_G | 249_M | 1.13 | 0.97 | |
| 164_T | 249_M | 1.124 | 0.97 | |
| 8_S | 34_A | 1.123 | 0.97 | |
| 90_I | 115_V | 1.121 | 0.97 | |
| 21_A | 227_A | 1.12 | 0.96 | |
| 69_R | 72_D | 1.12 | 0.96 | |
| 113_F | 118_L | 1.116 | 0.96 | |
| 141_T | 233_Y | 1.076 | 0.95 | |
| 107_T | 111_E | 1.074 | 0.95 | |
| 80_K | 134_S | 1.071 | 0.95 | |
| 18_L | 22_L | 1.07 | 0.95 | |
| 62_T | 111_E | 1.069 | 0.95 | |
| 35_T | 54_I | 1.068 | 0.95 | |
| 61_V | 119_G | 1.064 | 0.95 | |
| 87_N | 141_T | 1.059 | 0.95 | |
| 16_S | 42_K | 1.055 | 0.95 | |
| 121_L | 166_L | 1.052 | 0.95 | |
| 10_F | 70_A | 1.051 | 0.94 | |
| 156_Y | 160_K | 1.05 | 0.94 | |
| 57_V | 70_A | 1.045 | 0.94 | |
| 34_A | 57_V | 1.01 | 0.93 | |
| 21_A | 226_P | 1.008 | 0.93 | |
| 65_A | 68_Q | 1.007 | 0.93 | |
| 124_A | 166_L | 1.006 | 0.93 | |
| 8_S | 78_S | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3zv4A | 2 | 0.9963 | 100 | 0.15 | Contact Map | 0.796 |
| 1vl8A | 2 | 0.9074 | 100 | 0.166 | Contact Map | 0.804 |
| 3v8bA | 4 | 0.9333 | 100 | 0.168 | Contact Map | 0.845 |
| 3n74A | 4 | 0.9296 | 100 | 0.171 | Contact Map | 0.85 |
| 3grpA | 4 | 0.9 | 100 | 0.171 | Contact Map | 0.882 |
| 3op4A | 2 | 0.9 | 100 | 0.174 | Contact Map | 0.765 |
| 3cxtA | 1 | 0.9556 | 100 | 0.174 | Contact Map | 0.722 |
| 2c07A | 1 | 0.8963 | 100 | 0.175 | Contact Map | 0.758 |
| 4fn4A | 4 | 0.9037 | 100 | 0.175 | Contact Map | 0.932 |
| 4egfA | 8 | 0.9074 | 100 | 0.176 | Contact Map | 0.837 |
Sequence Conservation (Image Generated using WebLogo v3)