May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
RHTB - Homoserine/homoserine lactone efflux protein
UniProt: P0AG34 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11469
Length: 206 (205)
Sequences: 4882
Seq/Len: 23.81
RHTB
Paralog alert: 0.74 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: EAMB LEUE RHTB RHTC YAHN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
48_T 112_F 5.14 1.00
87_G 194_M 3.213 1.00
184_A 187_K 2.9 1.00
87_G 190_G 2.758 1.00
6_W 153_T 2.683 1.00
77_W 81_A 2.575 1.00
88_I 92_R 2.545 1.00
73_E 76_K 2.51 1.00
31_S 39_A 2.507 1.00
84_I 197_G 2.322 1.00
52_I 116_V 2.314 1.00
116_V 120_L 2.153 1.00
26_N 42_S 2.136 1.00
12_T 132_L 2.089 1.00
84_I 194_M 2.025 1.00
84_I 88_I 1.958 1.00
23_G 46_L 1.903 1.00
80_A 201_A 1.807 1.00
50_L 119_N 1.768 1.00
158_D 162_M 1.759 1.00
91_W 187_K 1.745 1.00
77_W 201_A 1.711 1.00
143_Q 146_Q 1.688 1.00
191_S 195_L 1.66 1.00
89_Q 92_R 1.625 1.00
27_T 31_S 1.622 1.00
30_T 34_H 1.614 1.00
109_R 113_Q 1.613 1.00
31_S 166_A 1.581 1.00
23_G 119_N 1.58 1.00
73_E 77_W 1.58 1.00
77_W 80_A 1.58 1.00
173_A 177_K 1.574 1.00
63_T 67_R 1.574 1.00
91_W 190_G 1.566 1.00
80_A 197_G 1.561 1.00
44_A 112_F 1.522 1.00
10_L 157_V 1.515 1.00
183_K 187_K 1.5 1.00
70_I 74_V 1.497 1.00
70_I 73_E 1.49 1.00
42_S 115_A 1.428 1.00
26_N 118_V 1.41 1.00
87_G 197_G 1.391 0.99
129_L 154_T 1.361 0.99
24_A 165_Y 1.358 0.99
28_M 169_A 1.358 0.99
184_A 188_I 1.355 0.99
39_A 43_I 1.347 0.99
55_V 59_V 1.322 0.99
23_G 50_L 1.314 0.99
82_Y 86_L 1.297 0.99
54_I 151_G 1.294 0.99
72_F 76_K 1.274 0.99
113_Q 117_F 1.272 0.99
142_P 145_M 1.269 0.99
161_V 165_Y 1.262 0.99
171_R 175_W 1.26 0.99
30_T 42_S 1.258 0.99
17_S 157_V 1.248 0.99
51_A 155_I 1.237 0.98
163_I 167_T 1.236 0.98
23_G 118_V 1.236 0.98
53_H 119_N 1.228 0.98
68_S 72_F 1.219 0.98
187_K 191_S 1.189 0.98
7_F 11_L 1.186 0.98
112_F 116_V 1.145 0.97
43_I 166_A 1.13 0.97
25_I 29_T 1.127 0.97
36_Y 167_T 1.119 0.96
30_T 114_R 1.118 0.96
171_R 174_L 1.105 0.96
121_T 130_A 1.103 0.96
50_L 125_S 1.096 0.96
91_W 194_M 1.093 0.96
38_G 111_L 1.075 0.95
185_L 189_F 1.071 0.95
9_Y 13_S 1.07 0.95
23_G 158_D 1.061 0.95
194_M 197_G 1.06 0.95
194_M 198_A 1.055 0.95
24_A 162_M 1.054 0.95
82_Y 85_W 1.053 0.95
65_F 68_S 1.053 0.95
20_P 124_K 1.05 0.94
156_V 160_I 1.047 0.94
178_G 181_Q 1.04 0.94
11_L 15_I 1.04 0.94
5_W 8_A 1.037 0.94
8_A 11_L 1.018 0.93
85_W 89_Q 1.017 0.93
27_T 46_L 1.012 0.93
74_V 77_W 1.006 0.93
164_G 168_L 1.005 0.93
12_T 16_L 1 0.92
110_H 113_Q 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2cfqA10.91264.30.945Contact Map0.21
2m67A10.37864.20.945Contact Map0.284
3j1zP20.83982.80.95Contact Map0.377
2h3oA10.28162.80.95Contact Map0.193
3o7qA10.93691.80.955Contact Map0.265
3wdoA10.47091.40.957Contact Map0.391
2wswA10.4660.90.962Contact Map0.235
1cmkI10.10680.90.963Contact Map0.036
2kv5A10.16020.80.964Contact Map0.371
2xq2A10.83980.80.964Contact Map0.628
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.174 seconds.