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SSUB - Aliphatic sulfonates import ATP-binding protein SsuB
UniProt: P0AAI1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12358
Length: 255 (209)
Sequences: 65985
Seq/Len: 315.72

SSUB
Paralog alert: 0.94 [within 20: 0.83] - ratio of genomes with paralogs
Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
41_A 200_A 3.249 1.00
13_L 33_H 3.042 1.00
38_Q 202_R 2.969 1.00
125_R 128_E 2.954 1.00
67_D 74_P 2.926 1.00
15_N 67_D 2.82 1.00
16_A 29_Q 2.815 1.00
25_I 28_N 2.703 1.00
118_A 123_E 2.7 1.00
81_D 152_G 2.695 1.00
40_V 204_L 2.677 1.00
13_L 69_L 2.599 1.00
35_P 38_Q 2.461 1.00
28_N 210_K 2.459 1.00
202_R 214_D 2.341 1.00
20_H 25_I 2.228 1.00
18_S 29_Q 2.209 1.00
14_L 17_V 2.169 1.00
112_A 150_R 2.141 1.00
18_S 25_I 2.125 1.00
18_S 65_A 2.073 1.00
71_G 152_G 2.07 1.00
19_K 56_L 2.065 1.00
114_R 126_A 2.027 1.00
117_L 126_A 2.005 1.00
97_V 133_L 1.981 1.00
15_N 69_L 1.942 1.00
98_I 127_G 1.845 1.00
98_I 126_A 1.807 1.00
98_I 114_R 1.806 1.00
150_R 184_F 1.773 1.00
177_S 181_E 1.755 1.00
204_L 211_I 1.745 1.00
38_Q 201_D 1.725 1.00
36_A 152_G 1.714 1.00
204_L 214_D 1.713 1.00
21_Y 26_V 1.708 1.00
119_A 177_S 1.692 1.00
16_A 31_D 1.691 1.00
98_I 113_A 1.631 1.00
19_K 64_T 1.604 1.00
115_R 119_A 1.578 1.00
110_R 114_R 1.525 1.00
98_I 102_G 1.494 1.00
98_I 110_R 1.49 1.00
20_H 64_T 1.48 1.00
128_E 132_A 1.474 1.00
19_K 61_E 1.445 1.00
87_Q 135_G 1.433 1.00
119_A 182_H 1.431 1.00
112_A 115_R 1.415 1.00
69_L 74_P 1.413 1.00
32_L 204_L 1.39 0.99
123_E 126_A 1.369 0.99
102_G 113_A 1.367 0.99
179_W 201_D 1.352 0.99
54_L 189_V 1.338 0.99
34_I 40_V 1.328 0.99
56_L 63_P 1.322 0.99
15_N 33_H 1.317 0.99
14_L 57_L 1.315 0.99
54_L 155_L 1.307 0.99
71_G 81_D 1.297 0.99
114_R 118_A 1.295 0.99
18_S 28_N 1.292 0.99
27_L 56_L 1.29 0.99
111_D 115_R 1.279 0.99
119_A 181_E 1.257 0.99
17_V 63_P 1.24 0.98
114_R 123_E 1.219 0.98
14_L 32_L 1.217 0.98
102_G 110_R 1.207 0.98
156_L 175_I 1.187 0.98
125_R 137_Q 1.185 0.98
40_V 214_D 1.181 0.98
97_V 141_V 1.176 0.98
95_K 99_D 1.167 0.97
96_S 99_D 1.164 0.97
101_V 148_I 1.162 0.97
14_L 53_L 1.156 0.97
15_N 31_D 1.151 0.97
35_P 202_R 1.151 0.97
100_N 145_R 1.142 0.97
190_T 196_A 1.136 0.97
57_L 187_L 1.135 0.97
207_E 212_G 1.133 0.97
112_A 116_A 1.131 0.97
55_R 61_E 1.094 0.96
174_L 177_S 1.084 0.96
20_H 26_V 1.074 0.95
179_W 186_V 1.065 0.95
53_L 206_I 1.058 0.95
30_L 53_L 1.057 0.95
58_A 84_M 1.057 0.95
39_F 179_W 1.052 0.95
150_R 182_H 1.05 0.94
39_F 186_V 1.047 0.94
19_K 52_T 1.045 0.94
117_L 122_L 1.044 0.94
101_V 117_L 1.044 0.94
36_A 71_G 1.044 0.94
21_Y 52_T 1.041 0.94
116_A 148_I 1.035 0.94
168_R 195_E 1.034 0.94
120_V 144_A 1.029 0.94
40_V 202_R 1.025 0.93
115_R 118_A 1.022 0.93
176_V 179_W 1.017 0.93
152_G 184_F 1.01 0.93
85_M 143_L 1.008 0.93
42_V 53_L 1.006 0.93
156_L 186_V 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1v43A111000.132Contact Map0.821
2yyzA10.96861000.133Contact Map0.811
1g29120.96861000.135Contact Map0.902
2it1A20.96861000.135Contact Map0.867
3tuiC411000.137Contact Map0.873
1oxxK10.96861000.137Contact Map0.812
3fvqA20.97251000.137Contact Map0.775
3rlfA20.96861000.138Contact Map0.844
3d31A20.95691000.138Contact Map0.822
1z47A211000.141Contact Map0.834

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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