| UniProt: | Q46927 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13084 | ||
| Length: | 268 (249) | ||
| Sequences: | 2632 | ||
| Seq/Len: | 10.57 |
| YGDL
Paralog alert: 0.63 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: MOEB THIF YGDL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 78_R | 98_P | 3.738 | 1.00 | |
| 90_A | 94_R | 3.703 | 1.00 | |
| 56_A | 101_R | 3.601 | 1.00 | |
| 83_L | 91_E | 3.59 | 1.00 | |
| 56_A | 103_T | 3.579 | 1.00 | |
| 76_A | 88_V | 3.36 | 1.00 | |
| 32_H | 56_A | 3.294 | 1.00 | |
| 62_M | 108_F | 3.263 | 1.00 | |
| 45_A | 126_I | 3.244 | 1.00 | |
| 32_H | 58_T | 3.194 | 1.00 | |
| 152_T | 248_F | 2.95 | 1.00 | |
| 200_G | 203_C | 2.936 | 1.00 | |
| 79_D | 95_Q | 2.931 | 1.00 | |
| 126_I | 256_A | 2.843 | 1.00 | |
| 124_Y | 256_A | 2.834 | 1.00 | |
| 80_N | 83_L | 2.732 | 1.00 | |
| 58_T | 122_Y | 2.716 | 1.00 | |
| 125_V | 142_C | 2.599 | 1.00 | |
| 84_A | 106_D | 2.528 | 1.00 | |
| 35_V | 46_A | 2.468 | 1.00 | |
| 255_H | 258_K | 2.443 | 1.00 | |
| 20_Y | 261_M | 2.317 | 1.00 | |
| 28_F | 257_L | 2.228 | 1.00 | |
| 75_H | 89_M | 2.219 | 1.00 | |
| 9_W | 29_A | 2.2 | 1.00 | |
| 90_A | 104_V | 2.191 | 1.00 | |
| 31_A | 260_M | 2.067 | 1.00 | |
| 87_E | 106_D | 2.012 | 1.00 | |
| 38_I | 59_L | 1.984 | 1.00 | |
| 93_I | 102_V | 1.973 | 1.00 | |
| 46_A | 93_I | 1.957 | 1.00 | |
| 86_A | 104_V | 1.94 | 1.00 | |
| 77_L | 92_R | 1.907 | 1.00 | |
| 87_E | 90_A | 1.864 | 1.00 | |
| 115_A | 144_R | 1.843 | 1.00 | |
| 86_A | 106_D | 1.823 | 1.00 | |
| 46_A | 59_L | 1.775 | 1.00 | |
| 109_V | 114_V | 1.775 | 1.00 | |
| 163_Q | 251_V | 1.762 | 1.00 | |
| 43_S | 75_H | 1.747 | 1.00 | |
| 129_I | 134_P | 1.723 | 1.00 | |
| 20_Y | 24_A | 1.712 | 1.00 | |
| 140_A | 202_D | 1.7 | 1.00 | |
| 129_I | 138_L | 1.689 | 1.00 | |
| 26_Q | 30_D | 1.626 | 1.00 | |
| 77_L | 95_Q | 1.611 | 1.00 | |
| 115_A | 145_N | 1.599 | 1.00 | |
| 58_T | 105_V | 1.564 | 1.00 | |
| 50_A | 93_I | 1.549 | 1.00 | |
| 141_Y | 145_N | 1.548 | 1.00 | |
| 14_G | 18_R | 1.54 | 1.00 | |
| 249_G | 253_V | 1.537 | 1.00 | |
| 48_A | 246_A | 1.506 | 1.00 | |
| 34_C | 122_Y | 1.496 | 1.00 | |
| 43_S | 47_E | 1.478 | 1.00 | |
| 247_T | 251_V | 1.447 | 1.00 | |
| 118_M | 142_C | 1.447 | 1.00 | |
| 45_A | 128_A | 1.446 | 1.00 | |
| 136_A | 206_S | 1.428 | 1.00 | |
| 107_D | 116_Q | 1.396 | 0.99 | |
| 34_C | 60_I | 1.391 | 0.99 | |
| 50_A | 100_C | 1.381 | 0.99 | |
| 87_E | 104_V | 1.374 | 0.99 | |
| 44_W | 47_E | 1.349 | 0.99 | |
| 152_T | 252_A | 1.338 | 0.99 | |
| 77_L | 80_N | 1.326 | 0.99 | |
| 58_T | 103_T | 1.324 | 0.99 | |
| 139_I | 200_G | 1.323 | 0.99 | |
| 139_I | 201_V | 1.31 | 0.99 | |
| 17_A | 22_E | 1.301 | 0.99 | |
| 80_N | 92_R | 1.3 | 0.99 | |
| 164_I | 189_F | 1.281 | 0.99 | |
| 114_V | 141_Y | 1.26 | 0.99 | |
| 140_A | 144_R | 1.256 | 0.99 | |
| 33_I | 256_A | 1.252 | 0.99 | |
| 139_I | 143_R | 1.249 | 0.99 | |
| 50_A | 57_I | 1.246 | 0.98 | |
| 47_E | 74_I | 1.223 | 0.98 | |
| 105_V | 122_Y | 1.222 | 0.98 | |
| 29_A | 99_E | 1.214 | 0.98 | |
| 13_F | 97_N | 1.202 | 0.98 | |
| 165_Q | 207_T | 1.192 | 0.98 | |
| 16_T | 71_N | 1.188 | 0.98 | |
| 167_T | 171_K | 1.186 | 0.98 | |
| 124_Y | 259_K | 1.182 | 0.98 | |
| 202_D | 255_H | 1.177 | 0.98 | |
| 33_I | 124_Y | 1.176 | 0.98 | |
| 9_W | 99_E | 1.171 | 0.98 | |
| 107_D | 113_N | 1.168 | 0.97 | |
| 93_I | 100_C | 1.166 | 0.97 | |
| 38_I | 89_M | 1.163 | 0.97 | |
| 243_M | 254_S | 1.161 | 0.97 | |
| 76_A | 80_N | 1.158 | 0.97 | |
| 94_R | 100_C | 1.158 | 0.97 | |
| 12_R | 78_R | 1.149 | 0.97 | |
| 50_A | 102_V | 1.14 | 0.97 | |
| 75_H | 93_I | 1.134 | 0.97 | |
| 150_V | 259_K | 1.129 | 0.97 | |
| 163_Q | 207_T | 1.114 | 0.96 | |
| 109_V | 113_N | 1.112 | 0.96 | |
| 126_I | 152_T | 1.092 | 0.96 | |
| 36_V | 138_L | 1.087 | 0.96 | |
| 111_P | 140_A | 1.082 | 0.96 | |
| 34_C | 118_M | 1.061 | 0.95 | |
| 113_N | 117_Y | 1.059 | 0.95 | |
| 52_T | 242_T | 1.059 | 0.95 | |
| 121_G | 147_I | 1.057 | 0.95 | |
| 115_A | 141_Y | 1.051 | 0.94 | |
| 52_T | 257_L | 1.05 | 0.94 | |
| 83_L | 87_E | 1.05 | 0.94 | |
| 28_F | 261_M | 1.047 | 0.94 | |
| 23_K | 27_L | 1.041 | 0.94 | |
| 51_R | 96_I | 1.038 | 0.94 | |
| 240_A | 244_V | 1.036 | 0.94 | |
| 103_T | 121_G | 1.036 | 0.94 | |
| 32_H | 103_T | 1.034 | 0.94 | |
| 124_Y | 150_V | 1.032 | 0.94 | |
| 246_A | 250_F | 1.017 | 0.93 | |
| 10_R | 22_E | 1.012 | 0.93 | |
| 165_Q | 259_K | 1.009 | 0.93 | |
| 136_A | 140_A | 1.009 | 0.93 | |
| 84_A | 87_E | 1.003 | 0.93 | |
| 47_E | 92_R | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zud1 | 2 | 0.7985 | 100 | 0.36 | Contact Map | 0.819 |
| 1jw9B | 1 | 0.8134 | 100 | 0.374 | Contact Map | 0.664 |
| 4gslA | 2 | 0.8507 | 100 | 0.381 | Contact Map | 0.593 |
| 3h8vA | 2 | 0.8396 | 100 | 0.404 | Contact Map | 0.749 |
| 3ruiA | 1 | 0.847 | 100 | 0.417 | Contact Map | 0.527 |
| 3h5nA | 4 | 0.8545 | 100 | 0.42 | Contact Map | 0.772 |
| 1tt5B | 2 | 0.8769 | 100 | 0.423 | Contact Map | 0.657 |
| 3cmmA | 2 | 0.8396 | 100 | 0.426 | Contact Map | 0.566 |
| 2nvuB | 1 | 0.8843 | 100 | 0.429 | Contact Map | 0.683 |
| 4ii2A | 1 | 0.8396 | 100 | 0.437 | Contact Map | 0.594 |
Sequence Conservation (Image Generated using WebLogo v3)