| UniProt: | P12282 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10154 | ||
| Length: | 249 (246) | ||
| Sequences: | 3667 | ||
| Seq/Len: | 14.91 |
| MOEB
Paralog alert: 0.70 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: MOEB THIF YGDL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 57_N | 102_A | 3.878 | 1.00 | |
| 91_R | 95_T | 3.754 | 1.00 | |
| 84_Q | 92_D | 3.557 | 1.00 | |
| 33_R | 59_T | 3.284 | 1.00 | |
| 57_N | 104_T | 3.283 | 1.00 | |
| 33_R | 57_N | 3.136 | 1.00 | |
| 63_F | 109_L | 2.998 | 1.00 | |
| 79_D | 99_P | 2.927 | 1.00 | |
| 80_A | 96_R | 2.907 | 1.00 | |
| 126_L | 208_A | 2.853 | 1.00 | |
| 77_H | 89_S | 2.845 | 1.00 | |
| 85_P | 107_N | 2.814 | 1.00 | |
| 59_T | 122_H | 2.806 | 1.00 | |
| 46_A | 126_L | 2.785 | 1.00 | |
| 8_E | 30_K | 2.606 | 1.00 | |
| 152_G | 200_I | 2.546 | 1.00 | |
| 81_T | 84_Q | 2.535 | 1.00 | |
| 125_V | 142_C | 2.466 | 1.00 | |
| 124_L | 208_A | 2.38 | 1.00 | |
| 207_E | 210_K | 2.38 | 1.00 | |
| 76_L | 90_A | 2.302 | 1.00 | |
| 222_K | 235_E | 2.279 | 1.00 | |
| 36_I | 47_S | 2.27 | 1.00 | |
| 47_S | 94_L | 2.232 | 1.00 | |
| 32_S | 212_L | 2.182 | 1.00 | |
| 91_R | 105_P | 2.146 | 1.00 | |
| 87_V | 105_P | 2.128 | 1.00 | |
| 88_E | 107_N | 2.07 | 1.00 | |
| 39_L | 60_L | 2.042 | 1.00 | |
| 35_L | 122_H | 1.952 | 1.00 | |
| 172_C | 175_C | 1.924 | 1.00 | |
| 21_F | 213_A | 1.888 | 1.00 | |
| 29_L | 209_I | 1.865 | 1.00 | |
| 87_V | 107_N | 1.832 | 1.00 | |
| 59_T | 106_V | 1.814 | 1.00 | |
| 47_S | 60_L | 1.8 | 1.00 | |
| 78_S | 96_R | 1.782 | 1.00 | |
| 78_S | 93_A | 1.683 | 1.00 | |
| 8_E | 100_H | 1.674 | 1.00 | |
| 94_L | 103_I | 1.663 | 1.00 | |
| 88_E | 105_P | 1.655 | 1.00 | |
| 141_G | 145_A | 1.654 | 1.00 | |
| 110_L | 115_L | 1.651 | 1.00 | |
| 59_T | 104_T | 1.647 | 1.00 | |
| 51_A | 94_L | 1.623 | 1.00 | |
| 129_T | 134_V | 1.619 | 1.00 | |
| 44_C | 76_L | 1.608 | 1.00 | |
| 116_A | 145_A | 1.574 | 1.00 | |
| 172_C | 244_C | 1.573 | 1.00 | |
| 116_A | 144_A | 1.571 | 1.00 | |
| 27_E | 31_D | 1.547 | 1.00 | |
| 46_A | 128_C | 1.533 | 1.00 | |
| 35_L | 61_L | 1.533 | 1.00 | |
| 161_I | 203_L | 1.528 | 1.00 | |
| 140_A | 174_R | 1.479 | 1.00 | |
| 129_T | 138_L | 1.467 | 1.00 | |
| 203_L | 233_F | 1.463 | 1.00 | |
| 13_N | 17_I | 1.461 | 1.00 | |
| 201_G | 205_A | 1.384 | 0.99 | |
| 21_F | 25_G | 1.368 | 0.99 | |
| 28_A | 32_S | 1.364 | 0.99 | |
| 37_V | 138_L | 1.34 | 0.99 | |
| 171_P | 221_G | 1.338 | 0.99 | |
| 11_R | 79_D | 1.327 | 0.99 | |
| 152_G | 204_Q | 1.32 | 0.99 | |
| 88_E | 91_R | 1.318 | 0.99 | |
| 49_Y | 198_G | 1.316 | 0.99 | |
| 95_T | 101_I | 1.315 | 0.99 | |
| 159_G | 200_I | 1.299 | 0.99 | |
| 244_C | 247_C | 1.284 | 0.99 | |
| 65_T | 85_P | 1.28 | 0.99 | |
| 91_R | 103_I | 1.254 | 0.99 | |
| 175_C | 244_C | 1.254 | 0.99 | |
| 39_L | 90_A | 1.254 | 0.99 | |
| 81_T | 93_A | 1.24 | 0.98 | |
| 51_A | 101_I | 1.235 | 0.98 | |
| 115_L | 141_G | 1.228 | 0.98 | |
| 199_V | 203_L | 1.224 | 0.98 | |
| 16_I | 23_F | 1.208 | 0.98 | |
| 45_A | 48_Q | 1.205 | 0.98 | |
| 85_P | 88_E | 1.204 | 0.98 | |
| 163_V | 211_M | 1.203 | 0.98 | |
| 108_A | 117_A | 1.193 | 0.98 | |
| 51_A | 58_L | 1.179 | 0.98 | |
| 195_P | 206_M | 1.179 | 0.98 | |
| 226_Y | 231_C | 1.176 | 0.98 | |
| 48_Q | 75_T | 1.173 | 0.98 | |
| 42_L | 204_Q | 1.173 | 0.98 | |
| 5_S | 8_E | 1.169 | 0.97 | |
| 84_Q | 88_E | 1.155 | 0.97 | |
| 77_H | 81_T | 1.134 | 0.97 | |
| 140_A | 144_A | 1.134 | 0.97 | |
| 124_L | 211_M | 1.131 | 0.97 | |
| 94_L | 101_I | 1.125 | 0.97 | |
| 76_L | 94_L | 1.112 | 0.96 | |
| 119_I | 142_C | 1.112 | 0.96 | |
| 34_V | 124_L | 1.097 | 0.96 | |
| 108_A | 114_E | 1.093 | 0.96 | |
| 24_D | 28_A | 1.072 | 0.95 | |
| 199_V | 226_Y | 1.071 | 0.95 | |
| 39_L | 87_V | 1.058 | 0.95 | |
| 136_N | 178_R | 1.056 | 0.95 | |
| 53_A | 209_I | 1.054 | 0.95 | |
| 64_D | 70_N | 1.049 | 0.94 | |
| 154_A | 197_I | 1.039 | 0.94 | |
| 143_F | 246_V | 1.037 | 0.94 | |
| 35_L | 59_T | 1.034 | 0.94 | |
| 139_N | 143_F | 1.033 | 0.94 | |
| 44_C | 48_Q | 1.03 | 0.94 | |
| 12_Y | 98_N | 1.022 | 0.93 | |
| 106_V | 122_H | 1.02 | 0.93 | |
| 120_A | 145_A | 1.02 | 0.93 | |
| 121_E | 147_V | 1.019 | 0.93 | |
| 93_A | 96_R | 1.019 | 0.93 | |
| 78_S | 81_T | 1.019 | 0.93 | |
| 226_Y | 233_F | 1.016 | 0.93 | |
| 84_Q | 89_S | 1.015 | 0.93 | |
| 52_S | 97_I | 1.014 | 0.93 | |
| 211_M | 218_P | 1.013 | 0.93 | |
| 92_D | 96_R | 1.013 | 0.93 | |
| 163_V | 179_L | 1.007 | 0.93 | |
| 23_F | 27_E | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1jw9B | 1 | 1 | 100 | 0.128 | Contact Map | 0.737 |
| 1zud1 | 2 | 0.9839 | 100 | 0.129 | Contact Map | 0.878 |
| 4gslA | 2 | 0.988 | 100 | 0.193 | Contact Map | 0.63 |
| 3h5nA | 4 | 0.996 | 100 | 0.203 | Contact Map | 0.797 |
| 3h8vA | 2 | 0.9839 | 100 | 0.21 | Contact Map | 0.804 |
| 1tt5B | 2 | 0.9839 | 100 | 0.221 | Contact Map | 0.707 |
| 3ruiA | 1 | 0.9839 | 100 | 0.224 | Contact Map | 0.572 |
| 2nvuB | 1 | 0.992 | 100 | 0.231 | Contact Map | 0.729 |
| 1y8qA | 2 | 0.9438 | 100 | 0.308 | Contact Map | 0.702 |
| 1y8qB | 2 | 0.9317 | 100 | 0.322 | Contact Map | 0.768 |
Sequence Conservation (Image Generated using WebLogo v3)