| UniProt: | P30138 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11587 | ||
| Length: | 251 (246) | ||
| Sequences: | 3678 | ||
| Seq/Len: | 14.95 |
| THIF
Paralog alert: 0.69 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: MOEB THIF YGDL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 54_T | 99_Q | 3.879 | 1.00 | |
| 88_Q | 92_T | 3.673 | 1.00 | |
| 81_R | 89_Q | 3.565 | 1.00 | |
| 54_T | 101_T | 3.305 | 1.00 | |
| 30_Q | 56_V | 3.25 | 1.00 | |
| 30_Q | 54_T | 3.164 | 1.00 | |
| 60_D | 106_R | 3.053 | 1.00 | |
| 76_T | 96_P | 2.974 | 1.00 | |
| 77_E | 93_Q | 2.896 | 1.00 | |
| 74_F | 86_V | 2.863 | 1.00 | |
| 82_P | 104_Q | 2.81 | 1.00 | |
| 123_L | 205_A | 2.793 | 1.00 | |
| 43_A | 123_L | 2.792 | 1.00 | |
| 56_V | 119_A | 2.787 | 1.00 | |
| 5_D | 27_L | 2.645 | 1.00 | |
| 78_D | 81_R | 2.575 | 1.00 | |
| 149_A | 197_M | 2.526 | 1.00 | |
| 204_E | 207_K | 2.432 | 1.00 | |
| 122_V | 139_C | 2.364 | 1.00 | |
| 73_L | 87_S | 2.323 | 1.00 | |
| 121_V | 205_A | 2.282 | 1.00 | |
| 33_I | 44_A | 2.254 | 1.00 | |
| 44_A | 91_L | 2.18 | 1.00 | |
| 218_E | 231_S | 2.169 | 1.00 | |
| 36_L | 57_L | 2.163 | 1.00 | |
| 29_S | 209_L | 2.107 | 1.00 | |
| 84_S | 102_A | 2.051 | 1.00 | |
| 88_Q | 102_A | 2.022 | 1.00 | |
| 85_Q | 104_Q | 2.004 | 1.00 | |
| 18_I | 210_S | 1.992 | 1.00 | |
| 32_L | 119_A | 1.941 | 1.00 | |
| 169_C | 172_C | 1.928 | 1.00 | |
| 26_L | 206_I | 1.919 | 1.00 | |
| 84_S | 104_Q | 1.886 | 1.00 | |
| 75_T | 93_Q | 1.775 | 1.00 | |
| 91_L | 100_L | 1.769 | 1.00 | |
| 56_V | 103_L | 1.718 | 1.00 | |
| 44_A | 57_L | 1.71 | 1.00 | |
| 5_D | 97_D | 1.688 | 1.00 | |
| 126_T | 131_T | 1.632 | 1.00 | |
| 48_A | 91_L | 1.627 | 1.00 | |
| 107_L | 112_L | 1.621 | 1.00 | |
| 32_L | 58_A | 1.613 | 1.00 | |
| 75_T | 90_R | 1.612 | 1.00 | |
| 138_A | 142_L | 1.599 | 1.00 | |
| 85_Q | 102_A | 1.591 | 1.00 | |
| 56_V | 101_T | 1.59 | 1.00 | |
| 113_K | 142_L | 1.589 | 1.00 | |
| 113_K | 141_A | 1.573 | 1.00 | |
| 169_C | 240_C | 1.569 | 1.00 | |
| 41_T | 73_L | 1.54 | 1.00 | |
| 10_S | 14_L | 1.526 | 1.00 | |
| 24_Q | 28_D | 1.513 | 1.00 | |
| 158_L | 200_L | 1.495 | 1.00 | |
| 43_A | 125_C | 1.487 | 1.00 | |
| 149_A | 201_Q | 1.478 | 1.00 | |
| 200_L | 229_W | 1.465 | 1.00 | |
| 137_A | 171_R | 1.46 | 1.00 | |
| 126_T | 135_I | 1.436 | 1.00 | |
| 85_Q | 88_Q | 1.421 | 1.00 | |
| 18_I | 22_G | 1.416 | 1.00 | |
| 198_G | 202_A | 1.4 | 0.99 | |
| 46_Y | 195_G | 1.387 | 0.99 | |
| 62_D | 82_P | 1.322 | 0.99 | |
| 8_R | 76_T | 1.279 | 0.99 | |
| 48_A | 98_I | 1.277 | 0.99 | |
| 240_C | 243_C | 1.251 | 0.99 | |
| 78_D | 90_R | 1.247 | 0.99 | |
| 25_K | 29_S | 1.246 | 0.98 | |
| 168_G | 217_G | 1.236 | 0.98 | |
| 42_P | 45_L | 1.224 | 0.98 | |
| 36_L | 87_S | 1.224 | 0.98 | |
| 172_C | 240_C | 1.223 | 0.98 | |
| 45_L | 72_I | 1.218 | 0.98 | |
| 112_L | 138_A | 1.214 | 0.98 | |
| 192_P | 203_L | 1.204 | 0.98 | |
| 74_F | 78_D | 1.204 | 0.98 | |
| 105_Q | 114_D | 1.202 | 0.98 | |
| 160_V | 208_L | 1.197 | 0.98 | |
| 92_T | 98_I | 1.195 | 0.98 | |
| 2_N | 5_D | 1.194 | 0.98 | |
| 13_I | 20_L | 1.185 | 0.98 | |
| 88_Q | 100_L | 1.182 | 0.98 | |
| 91_L | 98_I | 1.179 | 0.98 | |
| 196_V | 200_L | 1.175 | 0.98 | |
| 156_G | 197_M | 1.174 | 0.98 | |
| 222_F | 227_S | 1.173 | 0.98 | |
| 151_A | 194_V | 1.167 | 0.97 | |
| 39_L | 201_Q | 1.158 | 0.97 | |
| 73_L | 91_L | 1.156 | 0.97 | |
| 81_R | 85_Q | 1.153 | 0.97 | |
| 137_A | 141_A | 1.126 | 0.97 | |
| 75_T | 78_D | 1.123 | 0.97 | |
| 48_A | 55_L | 1.123 | 0.97 | |
| 82_P | 85_Q | 1.11 | 0.96 | |
| 34_I | 135_I | 1.104 | 0.96 | |
| 31_V | 121_V | 1.099 | 0.96 | |
| 116_V | 139_C | 1.097 | 0.96 | |
| 121_V | 209_L | 1.088 | 0.96 | |
| 117_A | 142_L | 1.081 | 0.95 | |
| 9_Y | 95_N | 1.076 | 0.95 | |
| 136_N | 170_Y | 1.065 | 0.95 | |
| 105_Q | 111_A | 1.061 | 0.95 | |
| 89_Q | 93_Q | 1.058 | 0.95 | |
| 121_V | 208_L | 1.057 | 0.95 | |
| 196_V | 222_F | 1.054 | 0.95 | |
| 21_D | 25_K | 1.049 | 0.94 | |
| 30_Q | 119_A | 1.047 | 0.94 | |
| 203_L | 222_F | 1.042 | 0.94 | |
| 208_L | 215_P | 1.042 | 0.94 | |
| 133_Q | 175_P | 1.042 | 0.94 | |
| 81_R | 86_V | 1.037 | 0.94 | |
| 160_V | 176_D | 1.034 | 0.94 | |
| 61_D | 67_N | 1.031 | 0.94 | |
| 140_V | 242_V | 1.031 | 0.94 | |
| 49_G | 94_L | 1.027 | 0.94 | |
| 169_C | 243_C | 1.025 | 0.93 | |
| 121_V | 147_I | 1.024 | 0.93 | |
| 136_N | 140_V | 1.022 | 0.93 | |
| 50_A | 206_I | 1.021 | 0.93 | |
| 36_L | 84_S | 1.021 | 0.93 | |
| 90_R | 93_Q | 1.019 | 0.93 | |
| 32_L | 56_V | 1.016 | 0.93 | |
| 20_L | 24_Q | 1.014 | 0.93 | |
| 103_L | 119_A | 1.014 | 0.93 | |
| 222_F | 229_W | 1.008 | 0.93 | |
| 41_T | 45_L | 1.007 | 0.93 | |
| 63_V | 74_F | 1.003 | 0.93 | |
| 171_R | 204_E | 1.002 | 0.92 | |
| 113_K | 138_A | 1.001 | 0.92 | |
| 30_Q | 101_T | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zud1 | 2 | 0.996 | 100 | 0.13 | Contact Map | 0.882 |
| 1jw9B | 1 | 0.9761 | 100 | 0.163 | Contact Map | 0.738 |
| 4gslA | 2 | 0.9841 | 100 | 0.215 | Contact Map | 0.636 |
| 3h5nA | 4 | 0.9761 | 100 | 0.226 | Contact Map | 0.793 |
| 3h8vA | 2 | 0.988 | 100 | 0.226 | Contact Map | 0.803 |
| 1tt5B | 2 | 0.9841 | 100 | 0.237 | Contact Map | 0.713 |
| 3ruiA | 1 | 0.9801 | 100 | 0.249 | Contact Map | 0.575 |
| 2nvuB | 1 | 0.9841 | 100 | 0.249 | Contact Map | 0.739 |
| 1y8qA | 2 | 0.9243 | 100 | 0.307 | Contact Map | 0.709 |
| 1y8qB | 2 | 0.9522 | 100 | 0.331 | Contact Map | 0.776 |
Sequence Conservation (Image Generated using WebLogo v3)