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OPENSEQ.org
TFAR - Tail fiber assembly protein homolog from lambdoid prophage Rac
UniProt: P77163 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13371
Length: 191 (190)
Sequences: 213
Seq/Len: 1.12
TFAR
Paralog alert: 0.64 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: TFAE TFAQ TFAR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
132_T 136_L 2.67 1.00
149_D 171_R 2.481 0.99
45_I 58_F 2.298 0.99
147_L 156_A 2.28 0.99
150_A 156_A 1.972 0.96
172_V 176_R 1.91 0.95
156_A 172_V 1.882 0.94
150_A 154_E 1.816 0.93
156_A 160_E 1.719 0.90
150_A 176_R 1.702 0.89
160_E 172_V 1.673 0.88
152_D 156_A 1.666 0.88
93_L 97_V 1.649 0.87
156_A 176_R 1.647 0.87
149_D 152_D 1.614 0.86
160_E 176_R 1.564 0.83
150_A 155_I 1.554 0.83
150_A 153_L 1.53 0.81
151_A 154_E 1.525 0.81
158_E 161_I 1.507 0.80
156_A 168_K 1.506 0.80
32_I 35_H 1.503 0.80
174_L 177_V 1.497 0.79
147_L 168_K 1.489 0.79
168_K 172_V 1.48 0.78
43_T 58_F 1.476 0.78
6_S 10_R 1.447 0.76
147_L 172_V 1.441 0.76
122_K 126_I 1.44 0.76
22_N 66_H 1.429 0.75
151_A 156_A 1.421 0.74
150_A 172_V 1.417 0.74
60_S 79_V 1.416 0.74
30_A 36_T 1.411 0.74
147_L 150_A 1.409 0.73
167_W 170_Y 1.381 0.71
5_M 11_T 1.372 0.71
168_K 176_R 1.345 0.68
149_D 156_A 1.321 0.66
10_R 30_A 1.311 0.65
10_R 35_H 1.307 0.65
149_D 154_E 1.307 0.65
152_D 168_K 1.301 0.65
76_V 97_V 1.294 0.64
168_K 171_R 1.279 0.63
104_G 107_Q 1.274 0.62
17_L 43_T 1.262 0.61
51_P 67_L 1.238 0.59
149_D 153_L 1.233 0.58
149_D 168_K 1.224 0.58
74_K 93_L 1.204 0.56
69_E 92_P 1.2 0.55
172_V 175_N 1.199 0.55
31_Y 77_Y 1.189 0.54
147_L 176_R 1.181 0.54
5_M 16_N 1.167 0.52
130_E 179_T 1.165 0.52
6_S 35_H 1.159 0.51
156_A 175_N 1.159 0.51
55_V 60_S 1.152 0.51
122_K 125_R 1.135 0.49
160_E 175_N 1.129 0.49
6_S 14_I 1.128 0.49
126_I 142_E 1.125 0.48
147_L 167_W 1.123 0.48
188_P 191_P 1.108 0.47
43_T 62_E 1.099 0.46
95_E 119_E 1.099 0.46
158_E 167_W 1.097 0.46
167_W 188_P 1.096 0.45
11_T 17_L 1.094 0.45
171_R 176_R 1.093 0.45
136_L 146_P 1.092 0.45
11_T 43_T 1.091 0.45
170_Y 188_P 1.084 0.44
30_A 35_H 1.083 0.44
167_W 191_P 1.08 0.44
107_Q 116_K 1.075 0.43
150_A 160_E 1.068 0.43
148_Q 152_D 1.065 0.43
106_F 124_F 1.054 0.42
150_A 168_K 1.048 0.41
147_L 160_E 1.042 0.40
150_A 175_N 1.042 0.40
66_H 98_T 1.036 0.40
8_Q 11_T 1.033 0.40
173_L 176_R 1.028 0.39
104_G 116_K 1.028 0.39
10_R 36_T 1.019 0.38
156_A 167_W 1.016 0.38
5_M 10_R 1.014 0.38
181_T 190_L 1.013 0.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2kz6A10.513199.70.762Contact Map0.223
2c7hA10.246190.965Contact Map0.034
1lm5A20.30898.60.965Contact Map0.122
3kvpA60.22518.20.966Contact Map0.133
3dsmA10.47126.80.967Contact Map0.083
4fvsA60.45555.60.968Contact Map0.054
1mdaH20.43984.80.969Contact Map0
2oizA20.42934.10.97Contact Map0
4ei0A20.48173.70.971Contact Map0.058
1aa0A10.36133.20.972Contact Map0.023
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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