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OPENSEQ.org
TFAQ - Tail fiber assembly protein homolog from lambdoid prophage Qin
UniProt: P76155 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13825
Length: 191 (190)
Sequences: 213
Seq/Len: 1.12
TFAQ
Paralog alert: 0.64 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: TFAE TFAQ TFAR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
132_T 136_L 2.674 1.00
149_D 171_R 2.477 0.99
45_I 58_F 2.301 0.99
147_L 156_A 2.274 0.99
150_A 156_A 1.972 0.96
172_V 176_R 1.906 0.95
156_A 172_V 1.886 0.94
150_A 154_E 1.819 0.93
156_A 160_E 1.729 0.90
150_A 176_R 1.698 0.89
160_E 172_V 1.682 0.89
152_D 156_A 1.665 0.88
93_L 97_V 1.663 0.88
156_A 176_R 1.637 0.87
149_D 152_D 1.619 0.86
160_E 176_R 1.563 0.83
150_A 155_I 1.558 0.83
151_A 154_E 1.535 0.82
150_A 153_L 1.524 0.81
158_E 161_I 1.508 0.80
32_I 35_H 1.506 0.80
156_A 168_K 1.503 0.80
147_L 168_K 1.486 0.79
174_L 177_V 1.486 0.79
168_K 172_V 1.484 0.79
43_T 58_F 1.48 0.78
6_S 10_R 1.445 0.76
147_L 172_V 1.441 0.76
122_K 126_I 1.437 0.75
22_N 66_H 1.428 0.75
150_A 172_V 1.422 0.74
30_A 36_T 1.418 0.74
151_A 156_A 1.417 0.74
60_S 79_V 1.409 0.73
147_L 150_A 1.408 0.73
167_W 170_Y 1.377 0.71
5_M 11_T 1.37 0.70
168_K 176_R 1.34 0.68
149_D 156_A 1.316 0.66
10_R 30_A 1.315 0.66
10_R 35_H 1.31 0.65
149_D 154_E 1.306 0.65
152_D 168_K 1.299 0.64
76_V 97_V 1.292 0.64
168_K 171_R 1.287 0.63
104_G 107_Q 1.274 0.62
17_L 43_T 1.264 0.61
51_P 67_L 1.25 0.60
149_D 153_L 1.229 0.58
149_D 168_K 1.226 0.58
74_K 93_L 1.208 0.56
172_V 175_N 1.203 0.56
69_E 92_P 1.201 0.55
31_Y 77_Y 1.184 0.54
130_E 179_T 1.173 0.53
5_M 16_N 1.173 0.53
147_L 176_R 1.168 0.52
156_A 175_N 1.165 0.52
55_V 60_S 1.151 0.51
6_S 35_H 1.144 0.50
122_K 125_R 1.137 0.49
160_E 175_N 1.135 0.49
147_L 167_W 1.133 0.49
6_S 14_I 1.124 0.48
126_I 142_E 1.122 0.48
171_R 176_R 1.104 0.46
188_P 191_P 1.103 0.46
95_E 119_E 1.099 0.46
158_E 167_W 1.099 0.46
11_T 17_L 1.095 0.45
136_L 146_P 1.094 0.45
43_T 62_E 1.091 0.45
11_T 43_T 1.089 0.45
150_A 160_E 1.084 0.44
167_W 188_P 1.083 0.44
30_A 35_H 1.08 0.44
170_Y 188_P 1.073 0.43
167_W 191_P 1.073 0.43
107_Q 116_K 1.072 0.43
148_Q 152_D 1.064 0.42
147_L 160_E 1.056 0.42
150_A 168_K 1.055 0.42
106_F 124_F 1.055 0.42
150_A 175_N 1.047 0.41
66_H 98_T 1.044 0.41
10_R 36_T 1.035 0.40
8_Q 11_T 1.03 0.39
173_L 176_R 1.03 0.39
104_G 116_K 1.024 0.39
5_M 10_R 1.021 0.38
151_A 171_R 1.012 0.38
181_T 190_L 1.009 0.37
156_A 167_W 1.008 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2kz6A10.513199.70.763Contact Map0.218
2c7hA10.24619.20.965Contact Map0.034
1lm5A20.30898.80.965Contact Map0.122
3kvpA60.22518.40.965Contact Map0.133
3dsmA10.47126.70.967Contact Map0.083
4fvsA60.42415.80.968Contact Map0.104
1mdaH20.43984.70.969Contact Map0
4ei0A20.481740.97Contact Map0.059
2oizA20.429340.97Contact Map0
1aa0A10.36133.20.972Contact Map0.021
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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