| UniProt: | P77150 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13940 | ||
| Length: | 287 (257) | ||
| Sequences: | 2876 | ||
| Seq/Len: | 11.19 |
| PDXY
Paralog alert: 0.62 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: PDXK PDXY THID |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 98_R | 139_A | 3.607 | 1.00 | |
| 91_E | 135_H | 3.507 | 1.00 | |
| 50_W | 66_G | 3.416 | 1.00 | |
| 53_C | 56_P | 3.174 | 1.00 | |
| 84_L | 93_I | 3.037 | 1.00 | |
| 160_N | 163_E | 3.021 | 1.00 | |
| 180_L | 226_T | 2.919 | 1.00 | |
| 37_N | 59_H | 2.787 | 1.00 | |
| 239_T | 242_E | 2.742 | 1.00 | |
| 81_S | 111_C | 2.699 | 1.00 | |
| 156_H | 170_E | 2.572 | 1.00 | |
| 61_T | 95_G | 2.497 | 1.00 | |
| 233_K | 238_A | 2.482 | 1.00 | |
| 150_L | 181_V | 2.439 | 1.00 | |
| 11_H | 20_S | 2.357 | 1.00 | |
| 130_E | 134_R | 2.348 | 1.00 | |
| 122_C | 126_P | 2.313 | 1.00 | |
| 98_R | 135_H | 2.309 | 1.00 | |
| 23_E | 30_G | 2.296 | 1.00 | |
| 65_Q | 96_I | 2.217 | 1.00 | |
| 233_K | 236_Q | 2.113 | 1.00 | |
| 60_L | 89_Q | 2.073 | 1.00 | |
| 64_V | 96_I | 2.042 | 1.00 | |
| 117_H | 121_G | 1.95 | 1.00 | |
| 7_A | 32_N | 1.921 | 1.00 | |
| 143_I | 171_L | 1.903 | 1.00 | |
| 124_V | 128_V | 1.89 | 1.00 | |
| 28_R | 232_V | 1.835 | 1.00 | |
| 37_N | 55_M | 1.824 | 1.00 | |
| 159_N | 163_E | 1.823 | 1.00 | |
| 97_V | 109_Y | 1.818 | 1.00 | |
| 248_T | 252_Y | 1.784 | 1.00 | |
| 90_G | 132_H | 1.765 | 1.00 | |
| 210_P | 256_V | 1.765 | 1.00 | |
| 81_S | 109_Y | 1.758 | 1.00 | |
| 51_T | 62_E | 1.732 | 1.00 | |
| 205_W | 241_Q | 1.717 | 1.00 | |
| 151_E | 157_A | 1.704 | 1.00 | |
| 54_V | 85_G | 1.676 | 1.00 | |
| 230_L | 244_L | 1.639 | 1.00 | |
| 4_N | 77_D | 1.638 | 1.00 | |
| 111_C | 140_S | 1.604 | 1.00 | |
| 96_I | 99_Q | 1.603 | 1.00 | |
| 178_I | 240_L | 1.601 | 1.00 | |
| 252_Y | 256_V | 1.596 | 1.00 | |
| 154_C | 171_L | 1.585 | 1.00 | |
| 65_Q | 69_A | 1.569 | 1.00 | |
| 26_M | 232_V | 1.562 | 1.00 | |
| 54_V | 86_S | 1.537 | 1.00 | |
| 61_T | 92_H | 1.533 | 1.00 | |
| 95_G | 135_H | 1.514 | 1.00 | |
| 158_V | 167_A | 1.508 | 1.00 | |
| 253_E | 256_V | 1.505 | 1.00 | |
| 151_E | 167_A | 1.497 | 1.00 | |
| 165_V | 204_A | 1.474 | 1.00 | |
| 57_P | 92_H | 1.468 | 1.00 | |
| 57_P | 88_E | 1.45 | 1.00 | |
| 172_I | 199_V | 1.447 | 1.00 | |
| 4_N | 75_T | 1.44 | 1.00 | |
| 11_H | 38_T | 1.423 | 1.00 | |
| 142_I | 180_L | 1.414 | 1.00 | |
| 207_I | 245_E | 1.406 | 0.99 | |
| 166_L | 169_R | 1.403 | 0.99 | |
| 233_K | 246_H | 1.399 | 0.99 | |
| 26_M | 233_K | 1.383 | 0.99 | |
| 168_A | 181_V | 1.377 | 0.99 | |
| 20_S | 32_N | 1.368 | 0.99 | |
| 238_A | 246_H | 1.36 | 0.99 | |
| 87_A | 127_G | 1.35 | 0.99 | |
| 13_V | 38_T | 1.313 | 0.99 | |
| 169_R | 173_A | 1.313 | 0.99 | |
| 55_M | 59_H | 1.308 | 0.99 | |
| 4_N | 72_K | 1.294 | 0.99 | |
| 241_Q | 245_E | 1.289 | 0.99 | |
| 242_E | 245_E | 1.282 | 0.99 | |
| 151_E | 158_V | 1.27 | 0.99 | |
| 61_T | 96_I | 1.268 | 0.99 | |
| 65_Q | 99_Q | 1.256 | 0.99 | |
| 84_L | 90_G | 1.256 | 0.99 | |
| 238_A | 242_E | 1.254 | 0.99 | |
| 170_E | 173_A | 1.24 | 0.98 | |
| 25_P | 229_L | 1.231 | 0.98 | |
| 141_D | 177_Q | 1.22 | 0.98 | |
| 8_I | 93_I | 1.217 | 0.98 | |
| 25_P | 225_V | 1.215 | 0.98 | |
| 53_C | 59_H | 1.214 | 0.98 | |
| 39_V | 62_E | 1.207 | 0.98 | |
| 44_H | 71_D | 1.204 | 0.98 | |
| 209_R | 248_T | 1.195 | 0.98 | |
| 234_L | 240_L | 1.183 | 0.98 | |
| 5_I | 28_R | 1.18 | 0.98 | |
| 88_E | 91_E | 1.166 | 0.97 | |
| 172_I | 201_A | 1.165 | 0.97 | |
| 163_E | 166_L | 1.161 | 0.97 | |
| 33_V | 64_V | 1.156 | 0.97 | |
| 116_G | 152_I | 1.153 | 0.97 | |
| 142_I | 240_L | 1.152 | 0.97 | |
| 161_V | 206_H | 1.149 | 0.97 | |
| 154_C | 170_E | 1.136 | 0.97 | |
| 156_H | 166_L | 1.123 | 0.97 | |
| 86_S | 89_Q | 1.119 | 0.96 | |
| 172_I | 176_P | 1.118 | 0.96 | |
| 165_V | 169_R | 1.117 | 0.96 | |
| 87_A | 91_E | 1.116 | 0.96 | |
| 105_P | 108_K | 1.109 | 0.96 | |
| 58_S | 62_E | 1.104 | 0.96 | |
| 94_L | 135_H | 1.1 | 0.96 | |
| 207_I | 248_T | 1.093 | 0.96 | |
| 203_E | 241_Q | 1.087 | 0.96 | |
| 245_E | 249_A | 1.082 | 0.96 | |
| 142_I | 178_I | 1.078 | 0.95 | |
| 5_I | 235_L | 1.074 | 0.95 | |
| 110_F | 234_L | 1.054 | 0.95 | |
| 137_L | 143_I | 1.054 | 0.95 | |
| 92_H | 95_G | 1.04 | 0.94 | |
| 29_L | 233_K | 1.027 | 0.94 | |
| 168_A | 199_V | 1.022 | 0.93 | |
| 90_G | 131_F | 1.02 | 0.93 | |
| 148_V | 185_A | 1.019 | 0.93 | |
| 50_W | 69_A | 1.016 | 0.93 | |
| 166_L | 170_E | 1.013 | 0.93 | |
| 20_S | 23_E | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pzsA | 2 | 0.993 | 100 | 0.338 | Contact Map | 0.631 |
| 2yxtA | 2 | 0.9791 | 100 | 0.362 | Contact Map | 0.632 |
| 2ddmA | 2 | 0.9373 | 100 | 0.398 | Contact Map | 0.657 |
| 3zs7A | 1 | 0.9756 | 100 | 0.407 | Contact Map | 0.597 |
| 3rm5A | 2 | 0.9547 | 100 | 0.437 | Contact Map | 0.703 |
| 3mbhA | 6 | 0.9477 | 100 | 0.443 | Contact Map | 0.678 |
| 3h74A | 1 | 0.9408 | 100 | 0.447 | Contact Map | 0.58 |
| 2i5bA | 5 | 0.9268 | 100 | 0.451 | Contact Map | 0.734 |
| 1ub0A | 1 | 0.8955 | 100 | 0.491 | Contact Map | 0.739 |
| 1jxhA | 2 | 0.9094 | 100 | 0.512 | Contact Map | 0.701 |
Sequence Conservation (Image Generated using WebLogo v3)