| UniProt: | P40191 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12642 | ||
| Length: | 283 (256) | ||
| Sequences: | 2917 | ||
| Seq/Len: | 11.39 |
| PDXK
Paralog alert: 0.62 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: PDXK PDXY THID |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 36_V | 46_V | 3.462 | 1.00 | |
| 104_K | 148_Y | 3.277 | 1.00 | |
| 111_T | 152_L | 3.216 | 1.00 | |
| 63_F | 79_A | 3.105 | 1.00 | |
| 66_G | 69_P | 2.981 | 1.00 | |
| 97_M | 106_L | 2.785 | 1.00 | |
| 193_V | 235_F | 2.714 | 1.00 | |
| 173_D | 176_S | 2.674 | 1.00 | |
| 94_T | 124_V | 2.563 | 1.00 | |
| 248_A | 251_D | 2.539 | 1.00 | |
| 53_L | 72_W | 2.517 | 1.00 | |
| 242_G | 247_K | 2.37 | 1.00 | |
| 42_N | 242_G | 2.351 | 1.00 | |
| 169_K | 183_S | 2.329 | 1.00 | |
| 44_L | 241_S | 2.308 | 1.00 | |
| 74_S | 108_E | 2.303 | 1.00 | |
| 39_I | 241_S | 2.277 | 1.00 | |
| 163_L | 194_V | 2.223 | 1.00 | |
| 143_E | 147_Q | 2.222 | 1.00 | |
| 39_I | 46_V | 2.185 | 1.00 | |
| 24_Q | 33_S | 2.129 | 1.00 | |
| 135_I | 139_P | 2.106 | 1.00 | |
| 78_R | 109_W | 2.106 | 1.00 | |
| 18_I | 44_L | 2.105 | 1.00 | |
| 111_T | 148_Y | 2.076 | 1.00 | |
| 20_A | 48_A | 1.99 | 1.00 | |
| 39_I | 44_L | 1.931 | 1.00 | |
| 130_D | 134_G | 1.914 | 1.00 | |
| 73_F | 102_Q | 1.906 | 1.00 | |
| 242_G | 245_K | 1.884 | 1.00 | |
| 53_L | 68_I | 1.865 | 1.00 | |
| 77_L | 109_W | 1.865 | 1.00 | |
| 33_S | 48_A | 1.82 | 1.00 | |
| 156_I | 184_L | 1.758 | 1.00 | |
| 137_V | 141_L | 1.718 | 1.00 | |
| 172_R | 176_S | 1.71 | 1.00 | |
| 67_A | 98_G | 1.698 | 1.00 | |
| 64_Y | 75_G | 1.686 | 1.00 | |
| 205_E | 220_S | 1.672 | 1.00 | |
| 222_S | 265_R | 1.666 | 1.00 | |
| 217_N | 250_T | 1.665 | 1.00 | |
| 49_V | 77_L | 1.647 | 1.00 | |
| 17_D | 90_R | 1.634 | 1.00 | |
| 110_L | 122_I | 1.623 | 1.00 | |
| 94_T | 122_I | 1.622 | 1.00 | |
| 257_G | 261_L | 1.618 | 1.00 | |
| 178_I | 216_V | 1.572 | 1.00 | |
| 239_L | 253_V | 1.569 | 1.00 | |
| 164_E | 170_N | 1.561 | 1.00 | |
| 58_P | 84_D | 1.553 | 1.00 | |
| 108_E | 148_Y | 1.546 | 1.00 | |
| 67_A | 99_T | 1.521 | 1.00 | |
| 109_W | 112_A | 1.514 | 1.00 | |
| 124_V | 153_A | 1.499 | 1.00 | |
| 32_N | 50_P | 1.48 | 1.00 | |
| 103_I | 145_Y | 1.47 | 1.00 | |
| 18_I | 39_I | 1.438 | 1.00 | |
| 206_M | 257_G | 1.427 | 1.00 | |
| 261_L | 265_R | 1.425 | 1.00 | |
| 78_R | 82_E | 1.422 | 1.00 | |
| 167_T | 184_L | 1.419 | 1.00 | |
| 191_W | 249_L | 1.414 | 1.00 | |
| 70_D | 105_I | 1.412 | 1.00 | |
| 20_A | 39_I | 1.404 | 0.99 | |
| 185_L | 211_V | 1.393 | 0.99 | |
| 74_S | 105_I | 1.369 | 0.99 | |
| 17_D | 85_A | 1.356 | 0.99 | |
| 242_G | 255_R | 1.331 | 0.99 | |
| 24_Q | 54_L | 1.329 | 0.99 | |
| 164_E | 180_A | 1.315 | 0.99 | |
| 17_D | 47_F | 1.307 | 0.99 | |
| 49_V | 73_F | 1.305 | 0.99 | |
| 17_D | 88_Q | 1.303 | 0.99 | |
| 155_G | 193_V | 1.301 | 0.99 | |
| 247_K | 251_D | 1.298 | 0.99 | |
| 179_A | 182_K | 1.293 | 0.99 | |
| 100_A | 140_D | 1.275 | 0.99 | |
| 70_D | 101_S | 1.272 | 0.99 | |
| 262_E | 265_R | 1.264 | 0.99 | |
| 219_I | 254_H | 1.258 | 0.99 | |
| 38_A | 238_Q | 1.25 | 0.99 | |
| 247_K | 255_R | 1.247 | 0.99 | |
| 164_E | 171_C | 1.242 | 0.98 | |
| 171_C | 180_A | 1.236 | 0.98 | |
| 74_S | 109_W | 1.224 | 0.98 | |
| 154_Q | 190_K | 1.213 | 0.98 | |
| 181_A | 194_V | 1.209 | 0.98 | |
| 155_G | 249_L | 1.187 | 0.98 | |
| 66_G | 72_W | 1.179 | 0.98 | |
| 78_R | 112_A | 1.176 | 0.98 | |
| 68_I | 72_W | 1.174 | 0.98 | |
| 38_A | 234_L | 1.171 | 0.98 | |
| 210_V | 219_I | 1.159 | 0.97 | |
| 251_D | 254_H | 1.157 | 0.97 | |
| 97_M | 103_I | 1.149 | 0.97 | |
| 221_H | 257_G | 1.148 | 0.97 | |
| 121_L | 154_Q | 1.147 | 0.97 | |
| 174_L | 218_V | 1.135 | 0.97 | |
| 55_S | 75_G | 1.12 | 0.96 | |
| 183_S | 186_S | 1.119 | 0.96 | |
| 169_K | 179_A | 1.118 | 0.96 | |
| 182_K | 186_S | 1.115 | 0.96 | |
| 99_T | 102_Q | 1.115 | 0.96 | |
| 185_L | 213_A | 1.113 | 0.96 | |
| 250_T | 254_H | 1.1 | 0.96 | |
| 177_A | 209_V | 1.099 | 0.96 | |
| 243_L | 249_L | 1.099 | 0.96 | |
| 185_L | 189_L | 1.096 | 0.96 | |
| 21_V | 106_L | 1.09 | 0.96 | |
| 215_S | 250_T | 1.09 | 0.96 | |
| 47_F | 85_A | 1.081 | 0.95 | |
| 174_L | 209_V | 1.074 | 0.95 | |
| 101_S | 104_K | 1.065 | 0.95 | |
| 47_F | 89_L | 1.062 | 0.95 | |
| 42_N | 245_K | 1.062 | 0.95 | |
| 42_N | 238_Q | 1.057 | 0.95 | |
| 155_G | 191_W | 1.049 | 0.94 | |
| 219_I | 257_G | 1.047 | 0.94 | |
| 167_T | 183_S | 1.046 | 0.94 | |
| 100_A | 104_K | 1.045 | 0.94 | |
| 44_L | 245_K | 1.044 | 0.94 | |
| 27_Y | 54_L | 1.042 | 0.94 | |
| 179_A | 183_S | 1.039 | 0.94 | |
| 38_A | 42_N | 1.039 | 0.94 | |
| 150_L | 156_I | 1.039 | 0.94 | |
| 71_E | 75_G | 1.037 | 0.94 | |
| 176_S | 179_A | 1.019 | 0.93 | |
| 64_Y | 72_W | 1.014 | 0.93 | |
| 254_H | 258_L | 1.01 | 0.93 | |
| 55_S | 72_W | 1.002 | 0.92 | |
| 17_D | 89_L | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ddmA | 2 | 0.9929 | 100 | 0.384 | Contact Map | 0.722 |
| 3pzsA | 2 | 0.9611 | 100 | 0.399 | Contact Map | 0.708 |
| 3rm5A | 2 | 0.9753 | 100 | 0.404 | Contact Map | 0.762 |
| 2yxtA | 2 | 0.9505 | 100 | 0.414 | Contact Map | 0.705 |
| 2i5bA | 5 | 0.9258 | 100 | 0.421 | Contact Map | 0.801 |
| 3mbhA | 6 | 0.947 | 100 | 0.428 | Contact Map | 0.777 |
| 3h74A | 1 | 0.9152 | 100 | 0.435 | Contact Map | 0.631 |
| 1ub0A | 1 | 0.9081 | 100 | 0.455 | Contact Map | 0.787 |
| 3zs7A | 1 | 0.9399 | 100 | 0.457 | Contact Map | 0.645 |
| 1jxhA | 2 | 0.9576 | 100 | 0.484 | Contact Map | 0.815 |
Sequence Conservation (Image Generated using WebLogo v3)