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OPENSEQ.org

HOKE - Protein HokE
UniProt: P77091 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14302
Length: 50 (50)
Sequences: 103
Seq/Len: 2.06

HOKE
Paralog alert: 0.81 [within 20: 0.19] - ratio of genomes with paralogs
Cluster includes: HOKA HOKB HOKC HOKD HOKE MOKC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_F 44_L 2.358 1.00
24_V 40_F 1.955 0.99
30_E 39_E 1.853 0.98
2_L 5_Y 1.678 0.96
8_A 15_L 1.643 0.95
2_L 6_A 1.639 0.95
4_K 7_L 1.589 0.94
27_S 31_F 1.568 0.94
30_E 45_A 1.393 0.87
46_Y 50_K 1.306 0.82
34_K 39_E 1.226 0.76
10_V 38_I 1.181 0.72
1_M 10_V 1.163 0.70
19_G 49_K 1.135 0.68
23_L 26_D 1.127 0.67
3_T 32_T 1.119 0.66
23_L 33_V 1.095 0.64
20_F 42_A 1.092 0.63
20_F 28_L 1.073 0.61
2_L 34_K 1.035 0.57
47_E 50_K 1.021 0.56
32_T 42_A 1.006 0.54
10_V 22_L 1.004 0.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3b55A10.824.60.893Contact Map0.343
3dxiA20.542.50.907Contact Map0.06
1dbgA10.862.30.908Contact Map0.167
4kytB20.52.10.91Contact Map0
1fjkA10.52.10.91Contact Map0
2ztjA10.562.10.911Contact Map0.095
4jn6A20.6220.911Contact Map0.002
1s94A20.621.80.914Contact Map
1ydnA40.581.70.915Contact Map0.11
2voyD10.441.60.916Contact Map0.354

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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