May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

YFGD - Uncharacterized protein YfgD
UniProt: P76569 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14200
Length: 119 (115)
Sequences: 2454
Seq/Len: 21.34

YFGD
Paralog alert: 0.78 [within 20: 0.09] - ratio of genomes with paralogs
Cluster includes: ARSC YFFB YFGD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
34_L 37_E 3.605 1.00
42_A 85_Q 3.356 1.00
87_M 94_M 2.849 1.00
24_K 30_P 2.612 1.00
79_S 82_A 2.487 1.00
41_D 44_T 2.437 1.00
47_D 51_I 2.109 1.00
42_A 46_R 2.067 1.00
49_L 84_I 1.997 1.00
72_N 75_D 1.993 1.00
57_A 80_E 1.814 1.00
9_H 32_V 1.777 1.00
7_I 99_V 1.738 1.00
36_L 92_K 1.699 1.00
85_Q 89_D 1.662 1.00
101_A 104_K 1.656 1.00
6_K 31_E 1.579 1.00
113_Q 116_E 1.566 1.00
66_D 70_E 1.559 1.00
67_L 90_N 1.541 1.00
46_R 84_I 1.524 1.00
7_I 20_L 1.5 1.00
21_N 25_E 1.489 1.00
22_L 26_N 1.482 1.00
49_L 60_L 1.476 1.00
40_A 94_M 1.46 1.00
78_L 86_A 1.434 1.00
24_K 29_E 1.431 1.00
42_A 84_I 1.417 1.00
99_V 114_V 1.398 0.99
33_V 44_T 1.398 0.99
52_L 60_L 1.392 0.99
51_I 105_A 1.377 0.99
15_K 18_E 1.368 0.99
20_L 32_V 1.333 0.99
33_V 38_T 1.276 0.99
49_L 53_G 1.233 0.98
48_L 98_I 1.23 0.98
60_L 98_I 1.208 0.98
54_M 60_L 1.208 0.98
44_T 100_V 1.207 0.98
52_L 98_I 1.203 0.98
13_C 96_R 1.2 0.98
106_R 117_I 1.188 0.98
61_M 87_M 1.185 0.98
56_S 59_E 1.179 0.98
44_T 47_D 1.17 0.97
48_L 100_V 1.122 0.97
43_A 46_R 1.119 0.96
61_M 83_L 1.095 0.96
10_N 16_S 1.093 0.96
9_H 20_L 1.087 0.96
46_R 81_E 1.06 0.95
45_L 84_I 1.058 0.95
111_P 115_L 1.044 0.94
67_L 70_E 1.041 0.94
65_E 92_K 1.033 0.94
7_I 16_S 1.013 0.93
67_L 92_K 1.011 0.93
112_E 115_L 1.004 0.93
8_Y 48_L 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1s3cA10.98321000.158Contact Map0.854
3gkxA20.98321000.172Contact Map0.834
1z3eA10.97481000.178Contact Map0.806
3rdwA20.99161000.182Contact Map0.848
3fz4A10.97481000.186Contact Map0.736
3f0iA20.97481000.187Contact Map0.865
2m46A10.99161000.189Contact Map0.766
2kokA10.96641000.192Contact Map0.485
3l78A10.96641000.196Contact Map0.671
1rw1A10.94961000.21Contact Map0.81

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.051 seconds.