| UniProt: | P76280 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14030 | ||
| Length: | 218 (209) | ||
| Sequences: | 7146 | ||
| Seq/Len: | 34.19 |
| YOBB
Paralog alert: 0.75 [within 20: 0.06] - ratio of genomes with paralogs Cluster includes: YAFV YBEM YOBB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 5_K | 204_Q | 3.442 | 1.00 | |
| 185_D | 189_R | 3.022 | 1.00 | |
| 119_R | 124_I | 2.961 | 1.00 | |
| 164_F | 167_Q | 2.746 | 1.00 | |
| 183_L | 203_G | 2.713 | 1.00 | |
| 7_A | 202_V | 2.462 | 1.00 | |
| 24_H | 198_S | 2.428 | 1.00 | |
| 25_H | 46_S | 2.422 | 1.00 | |
| 17_S | 20_E | 2.331 | 1.00 | |
| 7_A | 37_C | 2.286 | 1.00 | |
| 158_A | 193_R | 2.231 | 1.00 | |
| 195_D | 199_L | 2.229 | 1.00 | |
| 6_V | 173_L | 2.15 | 1.00 | |
| 30_R | 75_T | 2.148 | 1.00 | |
| 8_A | 173_L | 2.067 | 1.00 | |
| 30_R | 76_W | 2.029 | 1.00 | |
| 84_L | 97_A | 2.011 | 1.00 | |
| 8_A | 175_A | 1.989 | 1.00 | |
| 194_A | 199_L | 1.976 | 1.00 | |
| 35_Q | 202_V | 1.951 | 1.00 | |
| 26_L | 72_A | 1.923 | 1.00 | |
| 26_L | 68_P | 1.92 | 1.00 | |
| 38_Q | 121_S | 1.914 | 1.00 | |
| 126_V | 135_D | 1.855 | 1.00 | |
| 120_R | 123_T | 1.831 | 1.00 | |
| 171_A | 186_E | 1.829 | 1.00 | |
| 40_L | 78_M | 1.828 | 1.00 | |
| 194_A | 201_L | 1.789 | 1.00 | |
| 69_L | 82_A | 1.769 | 1.00 | |
| 41_V | 144_T | 1.751 | 1.00 | |
| 31_A | 35_Q | 1.742 | 1.00 | |
| 73_A | 80_I | 1.718 | 1.00 | |
| 71_Y | 75_T | 1.699 | 1.00 | |
| 81_I | 98_V | 1.696 | 1.00 | |
| 125_T | 142_L | 1.66 | 1.00 | |
| 159_R | 162_Q | 1.65 | 1.00 | |
| 184_W | 190_L | 1.646 | 1.00 | |
| 70_C | 99_F | 1.644 | 1.00 | |
| 24_H | 27_E | 1.631 | 1.00 | |
| 23_A | 27_E | 1.629 | 1.00 | |
| 29_V | 40_L | 1.564 | 1.00 | |
| 143_F | 170_I | 1.554 | 1.00 | |
| 9_A | 42_F | 1.553 | 1.00 | |
| 124_I | 141_S | 1.538 | 1.00 | |
| 79_T | 98_V | 1.505 | 1.00 | |
| 161_L | 174_M | 1.504 | 1.00 | |
| 100_A | 104_K | 1.503 | 1.00 | |
| 26_L | 30_R | 1.496 | 1.00 | |
| 79_T | 101_P | 1.489 | 1.00 | |
| 37_C | 202_V | 1.451 | 1.00 | |
| 9_A | 40_L | 1.447 | 1.00 | |
| 158_A | 162_Q | 1.417 | 1.00 | |
| 28_F | 31_A | 1.409 | 1.00 | |
| 165_S | 172_V | 1.408 | 1.00 | |
| 95_G | 107_G | 1.387 | 0.99 | |
| 41_V | 175_A | 1.383 | 0.99 | |
| 19_T | 23_A | 1.38 | 0.99 | |
| 185_D | 191_I | 1.376 | 0.99 | |
| 32_A | 200_L | 1.374 | 0.99 | |
| 192_V | 201_L | 1.362 | 0.99 | |
| 59_A | 63_L | 1.361 | 0.99 | |
| 39_L | 144_T | 1.361 | 0.99 | |
| 159_R | 166_H | 1.357 | 0.99 | |
| 173_L | 183_L | 1.34 | 0.99 | |
| 27_E | 31_A | 1.325 | 0.99 | |
| 81_I | 96_I | 1.287 | 0.99 | |
| 72_A | 76_W | 1.274 | 0.99 | |
| 25_H | 42_F | 1.272 | 0.99 | |
| 81_I | 144_T | 1.26 | 0.99 | |
| 86_V | 95_G | 1.257 | 0.99 | |
| 29_V | 80_I | 1.256 | 0.99 | |
| 142_L | 173_L | 1.252 | 0.99 | |
| 91_R | 110_H | 1.251 | 0.99 | |
| 131_P | 145_T | 1.235 | 0.98 | |
| 66_L | 97_A | 1.233 | 0.98 | |
| 131_P | 143_F | 1.226 | 0.98 | |
| 180_N | 193_R | 1.222 | 0.98 | |
| 71_Y | 74_T | 1.213 | 0.98 | |
| 20_E | 23_A | 1.195 | 0.98 | |
| 67_D | 71_Y | 1.193 | 0.98 | |
| 101_P | 121_S | 1.178 | 0.98 | |
| 11_Y | 28_F | 1.17 | 0.97 | |
| 37_C | 40_L | 1.17 | 0.97 | |
| 132_Q | 168_Y | 1.164 | 0.97 | |
| 93_I | 110_H | 1.161 | 0.97 | |
| 23_A | 68_P | 1.159 | 0.97 | |
| 79_T | 120_R | 1.153 | 0.97 | |
| 86_V | 93_I | 1.137 | 0.97 | |
| 96_I | 146_G | 1.117 | 0.96 | |
| 171_A | 191_I | 1.115 | 0.96 | |
| 62_D | 66_L | 1.11 | 0.96 | |
| 9_A | 200_L | 1.093 | 0.96 | |
| 22_V | 68_P | 1.087 | 0.96 | |
| 8_A | 181_S | 1.07 | 0.95 | |
| 11_Y | 25_H | 1.064 | 0.95 | |
| 29_V | 42_F | 1.061 | 0.95 | |
| 24_H | 28_F | 1.053 | 0.95 | |
| 30_R | 72_A | 1.053 | 0.95 | |
| 79_T | 100_A | 1.05 | 0.94 | |
| 98_V | 118_G | 1.044 | 0.94 | |
| 123_T | 141_S | 1.042 | 0.94 | |
| 22_V | 26_L | 1.037 | 0.94 | |
| 70_C | 104_K | 1.035 | 0.94 | |
| 77_R | 101_P | 1.034 | 0.94 | |
| 161_L | 172_V | 1.025 | 0.93 | |
| 88_Y | 93_I | 1.016 | 0.93 | |
| 84_L | 107_G | 1.007 | 0.93 | |
| 165_S | 184_W | 1.002 | 0.92 | |
| 47_L | 65_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3hkxA | 1 | 0.9954 | 100 | 0.158 | Contact Map | 0.722 |
| 2e11A | 4 | 0.9862 | 100 | 0.163 | Contact Map | 0.841 |
| 3p8kA | 2 | 0.9908 | 100 | 0.166 | Contact Map | 0.804 |
| 2dyuA | 2 | 0.9954 | 100 | 0.17 | Contact Map | 0.886 |
| 2w1vA | 2 | 0.9908 | 100 | 0.172 | Contact Map | 0.867 |
| 3ivzA | 2 | 0.9725 | 100 | 0.172 | Contact Map | 0.855 |
| 2vhhA | 4 | 0.9954 | 100 | 0.177 | Contact Map | 0.783 |
| 4f4hA | 2 | 0.9862 | 100 | 0.181 | Contact Map | 0.735 |
| 2uxyA | 1 | 0.9954 | 100 | 0.185 | Contact Map | 0.8 |
| 4lf0A | 1 | 0.9954 | 100 | 0.19 | Contact Map | 0.815 |
Sequence Conservation (Image Generated using WebLogo v3)