| UniProt: | P65367 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13170 | ||
| Length: | 149 (146) | ||
| Sequences: | 2682 | ||
| Seq/Len: | 18.37 |
| YQCA
Paralog alert: 0.55 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: FLAV FLAW MIOC YQCA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 91_A | 104_G | 3.944 | 1.00 | |
| 86_R | 117_Q | 3.629 | 1.00 | |
| 108_D | 118_R | 3.623 | 1.00 | |
| 105_K | 124_L | 3.188 | 1.00 | |
| 102_N | 106_Q | 2.845 | 1.00 | |
| 11_M | 66_D | 2.669 | 1.00 | |
| 110_L | 114_Q | 2.644 | 1.00 | |
| 110_L | 113_E | 2.535 | 1.00 | |
| 112_Q | 118_R | 2.344 | 1.00 | |
| 16_L | 20_E | 2.246 | 1.00 | |
| 89_V | 104_G | 1.992 | 1.00 | |
| 23_E | 35_V | 1.972 | 1.00 | |
| 90_I | 125_I | 1.906 | 1.00 | |
| 87_Y | 108_D | 1.851 | 1.00 | |
| 76_K | 110_L | 1.841 | 1.00 | |
| 23_E | 27_T | 1.836 | 1.00 | |
| 6_I | 23_E | 1.832 | 1.00 | |
| 87_Y | 112_Q | 1.768 | 1.00 | |
| 60_G | 63_D | 1.758 | 1.00 | |
| 4_I | 26_L | 1.741 | 1.00 | |
| 26_L | 145_G | 1.74 | 1.00 | |
| 120_G | 143_Q | 1.648 | 1.00 | |
| 108_D | 112_Q | 1.608 | 1.00 | |
| 9_G | 56_T | 1.604 | 1.00 | |
| 111_L | 116_A | 1.595 | 1.00 | |
| 9_G | 68_I | 1.582 | 1.00 | |
| 51_Y | 86_R | 1.559 | 1.00 | |
| 108_D | 122_M | 1.495 | 1.00 | |
| 87_Y | 118_R | 1.44 | 1.00 | |
| 15_S | 55_V | 1.416 | 1.00 | |
| 56_T | 107_F | 1.413 | 1.00 | |
| 10_T | 67_S | 1.41 | 1.00 | |
| 64_L | 103_G | 1.391 | 0.99 | |
| 55_V | 90_I | 1.378 | 0.99 | |
| 53_L | 144_W | 1.372 | 0.99 | |
| 54_V | 111_L | 1.371 | 0.99 | |
| 18_V | 137_S | 1.354 | 0.99 | |
| 43_D | 46_P | 1.32 | 0.99 | |
| 9_G | 67_S | 1.318 | 0.99 | |
| 109_A | 113_E | 1.301 | 0.99 | |
| 143_Q | 146_T | 1.295 | 0.99 | |
| 22_A | 55_V | 1.291 | 0.99 | |
| 69_V | 73_Q | 1.277 | 0.99 | |
| 23_E | 33_A | 1.245 | 0.98 | |
| 105_K | 122_M | 1.228 | 0.98 | |
| 93_G | 126_D | 1.217 | 0.98 | |
| 72_F | 107_F | 1.2 | 0.98 | |
| 7_F | 52_V | 1.184 | 0.98 | |
| 111_L | 118_R | 1.175 | 0.98 | |
| 125_I | 137_S | 1.174 | 0.98 | |
| 84_N | 117_Q | 1.169 | 0.97 | |
| 87_Y | 116_A | 1.163 | 0.97 | |
| 3_E | 32_K | 1.156 | 0.97 | |
| 63_D | 106_Q | 1.147 | 0.97 | |
| 5_G | 34_T | 1.114 | 0.96 | |
| 88_G | 144_W | 1.113 | 0.96 | |
| 58_T | 62_G | 1.109 | 0.96 | |
| 9_G | 65_P | 1.1 | 0.96 | |
| 60_G | 96_S | 1.09 | 0.96 | |
| 72_F | 106_Q | 1.089 | 0.96 | |
| 139_P | 143_Q | 1.084 | 0.96 | |
| 90_I | 123_L | 1.074 | 0.95 | |
| 52_V | 85_L | 1.07 | 0.95 | |
| 10_T | 15_S | 1.07 | 0.95 | |
| 88_G | 120_G | 1.067 | 0.95 | |
| 101_C | 104_G | 1.057 | 0.95 | |
| 40_E | 43_D | 1.057 | 0.95 | |
| 54_V | 107_F | 1.055 | 0.95 | |
| 57_S | 65_P | 1.04 | 0.94 | |
| 22_A | 53_L | 1.013 | 0.93 | |
| 53_L | 88_G | 1.011 | 0.93 | |
| 135_T | 139_P | 1.008 | 0.93 | |
| 118_R | 121_E | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1tllA | 2 | 0.9664 | 100 | 0.124 | Contact Map | 0.819 |
| 3qe2A | 2 | 0.9866 | 100 | 0.17 | Contact Map | 0.844 |
| 2bpoA | 2 | 0.9799 | 100 | 0.171 | Contact Map | 0.73 |
| 3hr4A | 4 | 0.9664 | 100 | 0.236 | Contact Map | 0.876 |
| 1bvyF | 1 | 0.9664 | 100 | 0.303 | Contact Map | 0.748 |
| 2hnaA | 1 | 0.9866 | 100 | 0.314 | Contact Map | 0.512 |
| 4h2dA | 2 | 0.9866 | 100 | 0.316 | Contact Map | 0.848 |
| 1ykgA | 1 | 0.9597 | 100 | 0.329 | Contact Map | 0.796 |
| 2wc1A | 1 | 0.9664 | 99.9 | 0.359 | Contact Map | 0.633 |
| 1ag9A | 2 | 0.953 | 99.9 | 0.375 | Contact Map | 0.775 |
Sequence Conservation (Image Generated using WebLogo v3)