| UniProt: | P52073 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12996 | ||
| Length: | 350 (343) | ||
| Sequences: | 3674 | ||
| Seq/Len: | 10.71 |
| GLCE
Paralog alert: 0.66 [within 20: 0.19] - ratio of genomes with paralogs Cluster includes: DLD GLCD GLCE YGCU |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 102_V | 166_I | 5.062 | 1.00 | |
| 19_I | 338_C | 4.558 | 1.00 | |
| 22_K | 338_C | 4.408 | 1.00 | |
| 267_A | 270_M | 3.764 | 1.00 | |
| 15_V | 25_L | 3.72 | 1.00 | |
| 103_A | 156_S | 3.561 | 1.00 | |
| 66_R | 165_E | 3.489 | 1.00 | |
| 274_G | 302_N | 3.289 | 1.00 | |
| 57_D | 60_E | 3.194 | 1.00 | |
| 126_I | 153_M | 3.139 | 1.00 | |
| 63_I | 74_I | 3.103 | 1.00 | |
| 125_R | 165_E | 3.095 | 1.00 | |
| 8_S | 125_R | 3.059 | 1.00 | |
| 52_G | 66_R | 2.986 | 1.00 | |
| 45_L | 162_V | 2.951 | 1.00 | |
| 187_Q | 273_P | 2.924 | 1.00 | |
| 153_M | 161_G | 2.886 | 1.00 | |
| 12_L | 133_H | 2.695 | 1.00 | |
| 63_I | 168_M | 2.647 | 1.00 | |
| 8_S | 133_H | 2.474 | 1.00 | |
| 79_E | 173_R | 2.435 | 1.00 | |
| 47_V | 162_V | 2.381 | 1.00 | |
| 28_Q | 31_N | 2.35 | 1.00 | |
| 53_I | 69_T | 2.246 | 1.00 | |
| 77_A | 80_S | 2.228 | 1.00 | |
| 83_Q | 170_V | 2.227 | 1.00 | |
| 15_V | 19_I | 2.207 | 1.00 | |
| 69_T | 74_I | 2.201 | 1.00 | |
| 126_I | 161_G | 2.179 | 1.00 | |
| 70_P | 73_T | 2.175 | 1.00 | |
| 129_G | 341_F | 2.174 | 1.00 | |
| 18_A | 43_Q | 2.173 | 1.00 | |
| 54_V | 66_R | 2.14 | 1.00 | |
| 102_V | 163_L | 2.118 | 1.00 | |
| 9_Q | 13_E | 2.036 | 1.00 | |
| 147_Y | 159_C | 2.026 | 1.00 | |
| 129_G | 335_L | 1.996 | 1.00 | |
| 55_N | 64_T | 1.99 | 1.00 | |
| 6_D | 10_A | 1.99 | 1.00 | |
| 17_Q | 21_D | 1.987 | 1.00 | |
| 65_A | 98_W | 1.983 | 1.00 | |
| 53_I | 77_A | 1.963 | 1.00 | |
| 6_D | 49_C | 1.937 | 1.00 | |
| 125_R | 135_R | 1.894 | 1.00 | |
| 56_Y | 77_A | 1.893 | 1.00 | |
| 96_A | 101_M | 1.877 | 1.00 | |
| 128_T | 132_K | 1.861 | 1.00 | |
| 58_P | 81_A | 1.84 | 1.00 | |
| 15_V | 341_F | 1.812 | 1.00 | |
| 73_T | 76_A | 1.812 | 1.00 | |
| 13_E | 16_N | 1.811 | 1.00 | |
| 15_V | 162_V | 1.8 | 1.00 | |
| 72_V | 76_A | 1.757 | 1.00 | |
| 262_S | 306_H | 1.75 | 1.00 | |
| 187_Q | 270_M | 1.749 | 1.00 | |
| 64_T | 165_E | 1.745 | 1.00 | |
| 61_L | 83_Q | 1.735 | 1.00 | |
| 27_I | 162_V | 1.726 | 1.00 | |
| 86_P | 120_F | 1.724 | 1.00 | |
| 185_S | 188_E | 1.719 | 1.00 | |
| 188_E | 191_S | 1.716 | 1.00 | |
| 64_T | 167_S | 1.708 | 1.00 | |
| 8_S | 12_L | 1.688 | 1.00 | |
| 8_S | 164_T | 1.685 | 1.00 | |
| 274_G | 303_A | 1.683 | 1.00 | |
| 271_D | 303_A | 1.669 | 1.00 | |
| 327_Y | 330_Q | 1.667 | 1.00 | |
| 60_E | 266_D | 1.657 | 1.00 | |
| 17_Q | 23_T | 1.655 | 1.00 | |
| 274_G | 299_I | 1.648 | 1.00 | |
| 57_D | 62_V | 1.636 | 1.00 | |
| 136_F | 150_S | 1.635 | 1.00 | |
| 308_T | 313_G | 1.633 | 1.00 | |
| 125_R | 164_T | 1.631 | 1.00 | |
| 299_I | 302_N | 1.593 | 1.00 | |
| 330_Q | 334_Q | 1.573 | 1.00 | |
| 270_M | 303_A | 1.568 | 1.00 | |
| 298_R | 302_N | 1.55 | 1.00 | |
| 270_M | 274_G | 1.546 | 1.00 | |
| 7_Y | 10_A | 1.543 | 1.00 | |
| 14_Q | 45_L | 1.542 | 1.00 | |
| 54_V | 165_E | 1.521 | 1.00 | |
| 51_R | 73_T | 1.52 | 1.00 | |
| 47_V | 50_H | 1.519 | 1.00 | |
| 25_L | 45_L | 1.488 | 1.00 | |
| 221_E | 225_K | 1.472 | 1.00 | |
| 321_S | 324_L | 1.449 | 1.00 | |
| 55_N | 139_E | 1.446 | 1.00 | |
| 132_K | 326_R | 1.403 | 0.99 | |
| 322_A | 326_R | 1.399 | 0.99 | |
| 127_I | 133_H | 1.396 | 0.99 | |
| 103_A | 163_L | 1.39 | 0.99 | |
| 78_L | 170_V | 1.384 | 0.99 | |
| 123_G | 138_G | 1.382 | 0.99 | |
| 12_L | 16_N | 1.379 | 0.99 | |
| 184_I | 192_E | 1.363 | 0.99 | |
| 152_L | 331_L | 1.36 | 0.99 | |
| 326_R | 330_Q | 1.356 | 0.99 | |
| 217_L | 231_L | 1.275 | 0.99 | |
| 10_A | 14_Q | 1.27 | 0.99 | |
| 29_G | 97_T | 1.262 | 0.99 | |
| 56_Y | 63_I | 1.257 | 0.99 | |
| 319_P | 322_A | 1.251 | 0.99 | |
| 48_R | 97_T | 1.246 | 0.98 | |
| 178_L | 225_K | 1.239 | 0.98 | |
| 19_I | 340_V | 1.221 | 0.98 | |
| 25_L | 340_V | 1.221 | 0.98 | |
| 121_V | 154_V | 1.216 | 0.98 | |
| 18_A | 25_L | 1.208 | 0.98 | |
| 11_L | 162_V | 1.206 | 0.98 | |
| 342_N | 345_R | 1.205 | 0.98 | |
| 187_Q | 191_S | 1.201 | 0.98 | |
| 225_K | 229_E | 1.201 | 0.98 | |
| 294_N | 298_R | 1.193 | 0.98 | |
| 11_L | 164_T | 1.192 | 0.98 | |
| 67_V | 166_I | 1.183 | 0.98 | |
| 258_L | 288_K | 1.18 | 0.98 | |
| 16_N | 20_S | 1.177 | 0.98 | |
| 196_W | 231_L | 1.176 | 0.98 | |
| 132_K | 323_P | 1.175 | 0.98 | |
| 148_D | 151_R | 1.175 | 0.98 | |
| 135_R | 165_E | 1.174 | 0.98 | |
| 74_I | 168_M | 1.171 | 0.98 | |
| 98_W | 166_I | 1.164 | 0.97 | |
| 16_N | 19_I | 1.155 | 0.97 | |
| 327_Y | 335_L | 1.153 | 0.97 | |
| 264_P | 267_A | 1.149 | 0.97 | |
| 87_C | 120_F | 1.147 | 0.97 | |
| 52_G | 69_T | 1.138 | 0.97 | |
| 120_F | 171_L | 1.131 | 0.97 | |
| 326_R | 329_Q | 1.128 | 0.97 | |
| 102_V | 121_V | 1.123 | 0.97 | |
| 77_A | 81_A | 1.117 | 0.96 | |
| 47_V | 67_V | 1.116 | 0.96 | |
| 182_R | 215_I | 1.11 | 0.96 | |
| 333_Q | 339_G | 1.109 | 0.96 | |
| 214_W | 240_F | 1.105 | 0.96 | |
| 145_A | 308_T | 1.092 | 0.96 | |
| 133_H | 164_T | 1.088 | 0.96 | |
| 123_G | 135_R | 1.085 | 0.96 | |
| 242_Q | 247_Q | 1.084 | 0.96 | |
| 163_L | 166_I | 1.079 | 0.95 | |
| 206_L | 215_I | 1.072 | 0.95 | |
| 125_R | 133_H | 1.069 | 0.95 | |
| 11_L | 47_V | 1.062 | 0.95 | |
| 11_L | 45_L | 1.054 | 0.95 | |
| 12_L | 127_I | 1.053 | 0.95 | |
| 156_S | 160_L | 1.051 | 0.94 | |
| 28_Q | 44_T | 1.045 | 0.94 | |
| 298_R | 320_L | 1.039 | 0.94 | |
| 332_K | 336_D | 1.038 | 0.94 | |
| 325_F | 329_Q | 1.033 | 0.94 | |
| 8_S | 50_H | 1.031 | 0.94 | |
| 33_K | 38_R | 1.029 | 0.94 | |
| 66_R | 69_T | 1.018 | 0.93 | |
| 50_H | 66_R | 1.014 | 0.93 | |
| 71_L | 101_M | 1.005 | 0.93 | |
| 102_V | 117_V | 1.005 | 0.93 | |
| 76_A | 80_S | 1.001 | 0.92 | |
| 27_I | 47_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pm9A | 6 | 0.9857 | 100 | 0.21 | Contact Map | 0.838 |
| 2uuuA | 4 | 0.98 | 100 | 0.212 | Contact Map | 0.735 |
| 4bbyA | 4 | 0.98 | 100 | 0.26 | Contact Map | 0.674 |
| 1f0xA | 2 | 0.9743 | 100 | 0.263 | Contact Map | 0.465 |
| 1wvfA | 1 | 0.98 | 100 | 0.295 | Contact Map | 0.694 |
| 2exrA | 1 | 0.9657 | 100 | 0.329 | Contact Map | 0.509 |
| 1w1oA | 1 | 0.9229 | 100 | 0.353 | Contact Map | 0.665 |
| 1e8gA | 2 | 0.9743 | 100 | 0.358 | Contact Map | 0.691 |
| 4fehA | 1 | 0.9771 | 100 | 0.463 | Contact Map | 0.66 |
| 2vfrA | 1 | 0.9486 | 100 | 0.568 | Contact Map | 0.62 |
Sequence Conservation (Image Generated using WebLogo v3)