| UniProt: | P39362 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12553 | ||
| Length: | 210 (208) | ||
| Sequences: | 2065 | ||
| Seq/Len: | 9.93 |
| SGCE
Paralog alert: 0.20 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ALSE RPE SGCE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_H | 17_R | 3.448 | 1.00 | |
| 177_A | 188_M | 2.993 | 1.00 | |
| 161_F | 164_T | 2.871 | 1.00 | |
| 172_I | 180_L | 2.616 | 1.00 | |
| 165_E | 186_Q | 2.424 | 1.00 | |
| 63_F | 82_P | 2.386 | 1.00 | |
| 120_D | 123_R | 2.338 | 1.00 | |
| 148_P | 179_Q | 2.31 | 1.00 | |
| 201_R | 205_A | 2.244 | 1.00 | |
| 85_I | 107_A | 2.215 | 1.00 | |
| 123_R | 156_K | 2.137 | 1.00 | |
| 197_S | 203_T | 2.065 | 1.00 | |
| 178_Q | 182_A | 2.051 | 1.00 | |
| 23_D | 59_H | 2.035 | 1.00 | |
| 68_A | 93_D | 1.995 | 1.00 | |
| 90_E | 117_T | 1.959 | 1.00 | |
| 38_S | 68_A | 1.959 | 1.00 | |
| 132_V | 157_V | 1.921 | 1.00 | |
| 32_L | 50_V | 1.911 | 1.00 | |
| 96_S | 128_E | 1.851 | 1.00 | |
| 158_R | 162_P | 1.85 | 1.00 | |
| 69_R | 72_R | 1.82 | 1.00 | |
| 134_V | 150_M | 1.787 | 1.00 | |
| 86_F | 112_V | 1.773 | 1.00 | |
| 146_F | 151_C | 1.752 | 1.00 | |
| 87_V | 95_P | 1.745 | 1.00 | |
| 78_A | 107_A | 1.741 | 1.00 | |
| 123_R | 160_A | 1.708 | 1.00 | |
| 75_N | 79_E | 1.702 | 1.00 | |
| 152_E | 155_Q | 1.701 | 1.00 | |
| 51_Q | 79_E | 1.685 | 1.00 | |
| 110_G | 131_G | 1.683 | 1.00 | |
| 22_L | 30_L | 1.679 | 1.00 | |
| 75_N | 101_E | 1.677 | 1.00 | |
| 136_T | 150_M | 1.665 | 1.00 | |
| 199_D | 202_A | 1.648 | 1.00 | |
| 29_S | 187_H | 1.637 | 1.00 | |
| 103_R | 109_A | 1.632 | 1.00 | |
| 21_A | 200_Y | 1.629 | 1.00 | |
| 71_Q | 98_T | 1.627 | 1.00 | |
| 101_E | 104_H | 1.621 | 1.00 | |
| 161_F | 186_Q | 1.577 | 1.00 | |
| 86_F | 131_G | 1.568 | 1.00 | |
| 181_A | 188_M | 1.555 | 1.00 | |
| 20_T | 24_N | 1.518 | 1.00 | |
| 89_A | 121_A | 1.498 | 1.00 | |
| 28_G | 208_A | 1.496 | 1.00 | |
| 71_Q | 92_L | 1.487 | 1.00 | |
| 38_S | 69_R | 1.481 | 1.00 | |
| 176_A | 180_L | 1.463 | 1.00 | |
| 75_N | 105_T | 1.462 | 1.00 | |
| 173_T | 176_A | 1.454 | 1.00 | |
| 109_A | 130_D | 1.451 | 1.00 | |
| 60_P | 84_W | 1.413 | 1.00 | |
| 54_A | 83_A | 1.413 | 1.00 | |
| 119_I | 157_V | 1.398 | 0.99 | |
| 45_F | 49_T | 1.369 | 0.99 | |
| 158_R | 161_F | 1.362 | 0.99 | |
| 134_V | 157_V | 1.359 | 0.99 | |
| 16_G | 20_T | 1.356 | 0.99 | |
| 54_A | 61_L | 1.353 | 0.99 | |
| 19_L | 53_V | 1.335 | 0.99 | |
| 50_V | 61_L | 1.329 | 0.99 | |
| 114_N | 138_E | 1.325 | 0.99 | |
| 2_I | 29_S | 1.319 | 0.99 | |
| 7_L | 30_L | 1.298 | 0.99 | |
| 202_A | 206_Q | 1.29 | 0.99 | |
| 84_W | 108_R | 1.286 | 0.99 | |
| 18_E | 200_Y | 1.279 | 0.99 | |
| 100_T | 104_H | 1.279 | 0.99 | |
| 99_L | 128_E | 1.274 | 0.99 | |
| 32_L | 61_L | 1.272 | 0.99 | |
| 72_R | 76_A | 1.254 | 0.99 | |
| 116_A | 138_E | 1.254 | 0.99 | |
| 18_E | 21_A | 1.249 | 0.99 | |
| 94_Y | 138_E | 1.244 | 0.98 | |
| 167_W | 189_V | 1.237 | 0.98 | |
| 94_Y | 97_E | 1.23 | 0.98 | |
| 78_A | 105_T | 1.216 | 0.98 | |
| 95_P | 111_L | 1.202 | 0.98 | |
| 190_I | 193_A | 1.196 | 0.98 | |
| 2_I | 165_E | 1.182 | 0.98 | |
| 119_I | 124_Y | 1.163 | 0.97 | |
| 174_L | 193_A | 1.149 | 0.97 | |
| 29_S | 165_E | 1.146 | 0.97 | |
| 95_P | 125_L | 1.145 | 0.97 | |
| 205_A | 209_T | 1.143 | 0.97 | |
| 4_H | 29_S | 1.13 | 0.97 | |
| 74_F | 105_T | 1.126 | 0.97 | |
| 120_D | 156_K | 1.12 | 0.96 | |
| 28_G | 60_P | 1.107 | 0.96 | |
| 100_T | 128_E | 1.103 | 0.96 | |
| 157_V | 166_C | 1.099 | 0.96 | |
| 84_W | 131_G | 1.097 | 0.96 | |
| 20_T | 23_D | 1.085 | 0.96 | |
| 155_Q | 182_A | 1.084 | 0.96 | |
| 99_L | 103_R | 1.084 | 0.96 | |
| 131_G | 187_H | 1.08 | 0.95 | |
| 99_L | 125_L | 1.056 | 0.95 | |
| 32_L | 45_F | 1.055 | 0.95 | |
| 179_Q | 182_A | 1.049 | 0.94 | |
| 95_P | 116_A | 1.048 | 0.94 | |
| 2_I | 187_H | 1.045 | 0.94 | |
| 111_L | 129_L | 1.045 | 0.94 | |
| 35_E | 40_I | 1.029 | 0.94 | |
| 165_E | 187_H | 1.026 | 0.93 | |
| 57_T | 61_L | 1.022 | 0.93 | |
| 202_A | 205_A | 1.018 | 0.93 | |
| 7_L | 32_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3cu2A | 2 | 0.981 | 100 | 0.34 | Contact Map | 0.678 |
| 3ctlA | 6 | 0.9952 | 100 | 0.438 | Contact Map | 0.833 |
| 4muzA | 2 | 0.9619 | 100 | 0.453 | Contact Map | 0.377 |
| 4dbdA | 1 | 0.9381 | 100 | 0.456 | Contact Map | 0.424 |
| 2yyuA | 2 | 0.9619 | 100 | 0.458 | Contact Map | 0.359 |
| 3inpA | 1 | 1 | 100 | 0.458 | Contact Map | 0.725 |
| 1dbtA | 3 | 0.9667 | 100 | 0.463 | Contact Map | 0.39 |
| 4df0A | 2 | 0.8952 | 100 | 0.463 | Contact Map | 0.347 |
| 1eixA | 4 | 0.9476 | 100 | 0.464 | Contact Map | 0.357 |
| 1rpxA | 3 | 1 | 100 | 0.466 | Contact Map | 0.791 |
Sequence Conservation (Image Generated using WebLogo v3)