| UniProt: | P0AG07 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11960 | ||
| Length: | 225 (216) | ||
| Sequences: | 2075 | ||
| Seq/Len: | 9.61 |
| RPE
Paralog alert: 0.20 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ALSE RPE SGCE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 17_R | 20_E | 3.56 | 1.00 | |
| 185_I | 196_F | 2.991 | 1.00 | |
| 165_I | 172_I | 2.755 | 1.00 | |
| 180_V | 188_I | 2.681 | 1.00 | |
| 173_R | 194_D | 2.44 | 1.00 | |
| 67_V | 86_A | 2.436 | 1.00 | |
| 152_P | 187_E | 2.355 | 1.00 | |
| 124_S | 127_D | 2.327 | 1.00 | |
| 209_K | 213_D | 2.292 | 1.00 | |
| 89_I | 111_C | 2.227 | 1.00 | |
| 127_D | 160_E | 2.177 | 1.00 | |
| 205_Q | 211_V | 2.052 | 1.00 | |
| 186_G | 190_A | 2.034 | 1.00 | |
| 26_L | 63_A | 2.011 | 1.00 | |
| 41_H | 72_K | 1.971 | 1.00 | |
| 72_K | 97_E | 1.96 | 1.00 | |
| 35_F | 53_L | 1.945 | 1.00 | |
| 94_E | 121_T | 1.933 | 1.00 | |
| 136_I | 161_V | 1.912 | 1.00 | |
| 162_R | 166_D | 1.879 | 1.00 | |
| 100_D | 132_K | 1.855 | 1.00 | |
| 163_R | 167_E | 1.847 | 1.00 | |
| 73_P | 76_R | 1.846 | 1.00 | |
| 138_L | 154_T | 1.815 | 1.00 | |
| 79_P | 83_A | 1.809 | 1.00 | |
| 90_T | 116_V | 1.804 | 1.00 | |
| 150_F | 155_L | 1.769 | 1.00 | |
| 156_D | 159_R | 1.758 | 1.00 | |
| 82_A | 111_C | 1.751 | 1.00 | |
| 25_A | 33_V | 1.748 | 1.00 | |
| 91_F | 99_V | 1.725 | 1.00 | |
| 127_D | 164_R | 1.715 | 1.00 | |
| 54_K | 83_A | 1.713 | 1.00 | |
| 114_G | 135_V | 1.705 | 1.00 | |
| 79_P | 105_L | 1.7 | 1.00 | |
| 24_K | 208_Y | 1.655 | 1.00 | |
| 75_D | 102_T | 1.653 | 1.00 | |
| 140_S | 154_T | 1.651 | 1.00 | |
| 32_V | 195_M | 1.639 | 1.00 | |
| 105_L | 108_E | 1.639 | 1.00 | |
| 107_K | 113_A | 1.636 | 1.00 | |
| 90_T | 135_V | 1.605 | 1.00 | |
| 207_D | 210_K | 1.597 | 1.00 | |
| 93_P | 125_Y | 1.55 | 1.00 | |
| 189_A | 196_F | 1.544 | 1.00 | |
| 75_D | 96_S | 1.531 | 1.00 | |
| 23_A | 27_A | 1.53 | 1.00 | |
| 41_H | 73_P | 1.525 | 1.00 | |
| 165_I | 194_D | 1.499 | 1.00 | |
| 181_K | 184_N | 1.476 | 1.00 | |
| 31_D | 216_R | 1.472 | 1.00 | |
| 79_P | 109_N | 1.455 | 1.00 | |
| 184_N | 188_I | 1.434 | 1.00 | |
| 57_R | 65_I | 1.433 | 1.00 | |
| 64_P | 88_I | 1.432 | 1.00 | |
| 113_A | 134_D | 1.409 | 0.99 | |
| 48_I | 52_V | 1.406 | 0.99 | |
| 19_G | 23_A | 1.391 | 0.99 | |
| 123_L | 161_V | 1.386 | 0.99 | |
| 57_R | 87_S | 1.383 | 0.99 | |
| 118_N | 142_N | 1.363 | 0.99 | |
| 53_L | 65_I | 1.345 | 0.99 | |
| 10_I | 33_V | 1.338 | 0.99 | |
| 104_Q | 108_E | 1.335 | 0.99 | |
| 162_R | 165_I | 1.328 | 0.99 | |
| 22_T | 56_L | 1.327 | 0.99 | |
| 210_K | 214_E | 1.31 | 0.99 | |
| 5_L | 32_V | 1.306 | 0.99 | |
| 138_L | 161_V | 1.303 | 0.99 | |
| 76_R | 80_D | 1.3 | 0.99 | |
| 103_L | 132_K | 1.298 | 0.99 | |
| 21_D | 208_Y | 1.288 | 0.99 | |
| 120_A | 142_N | 1.28 | 0.99 | |
| 88_I | 112_K | 1.276 | 0.99 | |
| 98_H | 142_N | 1.274 | 0.99 | |
| 98_H | 101_R | 1.273 | 0.99 | |
| 35_F | 65_I | 1.255 | 0.98 | |
| 21_D | 24_K | 1.251 | 0.98 | |
| 99_V | 115_L | 1.241 | 0.98 | |
| 82_A | 109_N | 1.238 | 0.98 | |
| 175_E | 197_V | 1.234 | 0.98 | |
| 198_A | 201_A | 1.215 | 0.98 | |
| 32_V | 173_R | 1.191 | 0.98 | |
| 213_D | 217_S | 1.186 | 0.98 | |
| 182_V | 201_A | 1.179 | 0.97 | |
| 7_A | 32_V | 1.159 | 0.97 | |
| 5_L | 173_R | 1.149 | 0.97 | |
| 159_R | 190_A | 1.147 | 0.97 | |
| 78_V | 109_N | 1.144 | 0.97 | |
| 31_D | 64_P | 1.141 | 0.97 | |
| 130_M | 170_F | 1.138 | 0.97 | |
| 123_L | 128_Y | 1.132 | 0.96 | |
| 104_Q | 132_K | 1.117 | 0.96 | |
| 99_V | 129_V | 1.101 | 0.96 | |
| 88_I | 135_V | 1.101 | 0.96 | |
| 135_V | 195_M | 1.101 | 0.96 | |
| 103_L | 107_K | 1.084 | 0.95 | |
| 161_V | 174_L | 1.077 | 0.95 | |
| 23_A | 26_L | 1.061 | 0.94 | |
| 124_S | 160_E | 1.058 | 0.94 | |
| 35_F | 48_I | 1.054 | 0.94 | |
| 61_I | 65_I | 1.05 | 0.94 | |
| 187_E | 190_A | 1.048 | 0.94 | |
| 5_L | 195_M | 1.044 | 0.94 | |
| 115_L | 129_V | 1.036 | 0.93 | |
| 99_V | 120_A | 1.035 | 0.93 | |
| 173_R | 195_M | 1.035 | 0.93 | |
| 158_L | 176_V | 1.032 | 0.93 | |
| 115_L | 133_L | 1.027 | 0.93 | |
| 210_K | 213_D | 1.024 | 0.93 | |
| 103_L | 129_V | 1.016 | 0.93 | |
| 11_L | 146_G | 1.014 | 0.93 | |
| 38_M | 43_V | 1.005 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3cu2A | 2 | 0.9556 | 100 | 0.347 | Contact Map | 0.655 |
| 3inpA | 1 | 0.9822 | 100 | 0.453 | Contact Map | 0.716 |
| 3ctlA | 6 | 0.9778 | 100 | 0.454 | Contact Map | 0.826 |
| 1rpxA | 3 | 0.9822 | 100 | 0.474 | Contact Map | 0.786 |
| 4df0A | 2 | 0.88 | 100 | 0.475 | Contact Map | 0.337 |
| 2yyuA | 2 | 0.9378 | 100 | 0.477 | Contact Map | 0.359 |
| 4muzA | 2 | 0.9244 | 100 | 0.477 | Contact Map | 0.369 |
| 4dbdA | 1 | 0.9111 | 100 | 0.482 | Contact Map | 0.408 |
| 1dbtA | 3 | 0.9378 | 100 | 0.483 | Contact Map | 0.404 |
| 1eixA | 4 | 0.9244 | 100 | 0.484 | Contact Map | 0.357 |
Sequence Conservation (Image Generated using WebLogo v3)