| UniProt: | P32719 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11957 | ||
| Length: | 231 (212) | ||
| Sequences: | 2079 | ||
| Seq/Len: | 9.81 |
| ALSE
Paralog alert: 0.20 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: ALSE RPE SGCE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_K | 17_E | 3.537 | 1.00 | |
| 181_Y | 192_F | 3.028 | 1.00 | |
| 161_R | 168_Y | 2.841 | 1.00 | |
| 176_C | 184_L | 2.728 | 1.00 | |
| 169_E | 190_D | 2.471 | 1.00 | |
| 62_C | 81_A | 2.453 | 1.00 | |
| 120_E | 123_K | 2.355 | 1.00 | |
| 148_P | 183_K | 2.352 | 1.00 | |
| 203_A | 207_D | 2.266 | 1.00 | |
| 84_I | 107_M | 2.218 | 1.00 | |
| 123_K | 156_E | 2.162 | 1.00 | |
| 199_L | 205_N | 2.062 | 1.00 | |
| 67_T | 93_G | 2.049 | 1.00 | |
| 37_H | 67_T | 2.016 | 1.00 | |
| 182_E | 186_A | 1.99 | 1.00 | |
| 31_I | 49_V | 1.97 | 1.00 | |
| 158_K | 162_E | 1.938 | 1.00 | |
| 132_I | 157_L | 1.917 | 1.00 | |
| 96_F | 128_K | 1.909 | 1.00 | |
| 89_E | 117_T | 1.903 | 1.00 | |
| 134_V | 150_M | 1.841 | 1.00 | |
| 159_A | 163_R | 1.832 | 1.00 | |
| 68_R | 71_D | 1.8 | 1.00 | |
| 85_T | 112_I | 1.795 | 1.00 | |
| 152_D | 155_A | 1.786 | 1.00 | |
| 146_F | 151_L | 1.779 | 1.00 | |
| 86_L | 95_A | 1.778 | 1.00 | |
| 74_A | 78_R | 1.764 | 1.00 | |
| 77_A | 107_M | 1.755 | 1.00 | |
| 50_S | 78_R | 1.75 | 1.00 | |
| 22_I | 29_F | 1.731 | 1.00 | |
| 74_A | 101_E | 1.728 | 1.00 | |
| 123_K | 160_W | 1.724 | 1.00 | |
| 201_N | 204_E | 1.713 | 1.00 | |
| 110_G | 131_K | 1.701 | 1.00 | |
| 28_Y | 191_V | 1.701 | 1.00 | |
| 136_T | 150_M | 1.698 | 1.00 | |
| 21_F | 202_H | 1.644 | 1.00 | |
| 70_Q | 98_L | 1.634 | 1.00 | |
| 85_T | 131_K | 1.617 | 1.00 | |
| 101_E | 104_R | 1.608 | 1.00 | |
| 103_R | 109_V | 1.606 | 1.00 | |
| 185_M | 192_F | 1.573 | 1.00 | |
| 37_H | 68_R | 1.556 | 1.00 | |
| 161_R | 190_D | 1.516 | 1.00 | |
| 70_Q | 92_N | 1.514 | 1.00 | |
| 88_P | 121_A | 1.467 | 1.00 | |
| 177_N | 180_T | 1.465 | 1.00 | |
| 109_V | 130_D | 1.46 | 1.00 | |
| 74_A | 105_H | 1.452 | 1.00 | |
| 180_T | 184_L | 1.45 | 1.00 | |
| 20_E | 23_D | 1.443 | 1.00 | |
| 27_D | 210_W | 1.434 | 1.00 | |
| 44_L | 48_F | 1.432 | 1.00 | |
| 16_K | 20_E | 1.417 | 1.00 | |
| 53_K | 60_L | 1.392 | 0.99 | |
| 53_K | 82_D | 1.391 | 0.99 | |
| 59_P | 83_F | 1.391 | 0.99 | |
| 158_K | 161_R | 1.378 | 0.99 | |
| 114_N | 138_D | 1.37 | 0.99 | |
| 119_V | 157_L | 1.367 | 0.99 | |
| 134_V | 157_L | 1.362 | 0.99 | |
| 49_V | 60_L | 1.36 | 0.99 | |
| 19_I | 52_V | 1.339 | 0.99 | |
| 18_Q | 202_H | 1.322 | 0.99 | |
| 99_I | 128_K | 1.313 | 0.99 | |
| 100_D | 104_R | 1.308 | 0.99 | |
| 31_I | 60_L | 1.304 | 0.99 | |
| 204_E | 208_E | 1.289 | 0.99 | |
| 83_F | 108_K | 1.288 | 0.99 | |
| 116_E | 138_D | 1.287 | 0.99 | |
| 7_L | 29_F | 1.281 | 0.99 | |
| 71_D | 75_Q | 1.279 | 0.99 | |
| 94_Q | 138_D | 1.258 | 0.99 | |
| 95_A | 111_L | 1.24 | 0.98 | |
| 77_A | 105_H | 1.238 | 0.98 | |
| 94_Q | 97_R | 1.236 | 0.98 | |
| 171_E | 193_I | 1.233 | 0.98 | |
| 18_Q | 21_F | 1.232 | 0.98 | |
| 194_V | 197_S | 1.225 | 0.98 | |
| 4_S | 28_Y | 1.185 | 0.98 | |
| 119_V | 124_Y | 1.174 | 0.97 | |
| 28_Y | 169_E | 1.17 | 0.97 | |
| 73_I | 105_H | 1.169 | 0.97 | |
| 178_Q | 197_S | 1.153 | 0.97 | |
| 126_I | 166_L | 1.136 | 0.97 | |
| 95_A | 125_Y | 1.135 | 0.97 | |
| 155_A | 186_A | 1.129 | 0.97 | |
| 131_K | 191_V | 1.119 | 0.96 | |
| 27_D | 59_P | 1.107 | 0.96 | |
| 31_I | 44_L | 1.086 | 0.95 | |
| 100_D | 128_K | 1.085 | 0.95 | |
| 83_F | 131_K | 1.081 | 0.95 | |
| 183_K | 186_A | 1.078 | 0.95 | |
| 111_L | 129_A | 1.074 | 0.95 | |
| 120_E | 156_E | 1.073 | 0.95 | |
| 157_L | 170_I | 1.068 | 0.95 | |
| 204_E | 207_D | 1.057 | 0.95 | |
| 99_I | 103_R | 1.057 | 0.95 | |
| 95_A | 116_E | 1.055 | 0.94 | |
| 2_K | 28_Y | 1.048 | 0.94 | |
| 154_L | 170_I | 1.04 | 0.94 | |
| 154_L | 172_V | 1.036 | 0.94 | |
| 56_A | 60_L | 1.033 | 0.94 | |
| 8_M | 142_A | 1.023 | 0.93 | |
| 99_I | 125_Y | 1.022 | 0.93 | |
| 17_E | 21_F | 1.015 | 0.93 | |
| 155_A | 159_A | 1.014 | 0.93 | |
| 151_L | 183_K | 1.013 | 0.93 | |
| 7_L | 31_I | 1.011 | 0.93 | |
| 207_D | 211_R | 1.011 | 0.93 | |
| 38_F | 89_E | 1.005 | 0.92 | |
| 34_M | 39_V | 1.005 | 0.92 | |
| 111_L | 125_Y | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3cu2A | 2 | 0.9048 | 100 | 0.391 | Contact Map | 0.649 |
| 3ctlA | 6 | 0.974 | 100 | 0.444 | Contact Map | 0.822 |
| 3inpA | 1 | 0.9307 | 100 | 0.501 | Contact Map | 0.704 |
| 1rpxA | 3 | 0.9307 | 100 | 0.51 | Contact Map | 0.777 |
| 2yyuA | 2 | 0.9177 | 100 | 0.511 | Contact Map | 0.351 |
| 1dbtA | 3 | 0.8961 | 100 | 0.511 | Contact Map | 0.389 |
| 4df0A | 2 | 0.8398 | 100 | 0.513 | Contact Map | 0.331 |
| 4muzA | 2 | 0.8745 | 100 | 0.514 | Contact Map | 0.391 |
| 4dbdA | 1 | 0.9091 | 100 | 0.514 | Contact Map | 0.419 |
| 1tqjA | 6 | 0.9567 | 100 | 0.516 | Contact Map | 0.819 |
Sequence Conservation (Image Generated using WebLogo v3)