| UniProt: | P37678 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12285 | ||
| Length: | 220 (205) | ||
| Sequences: | 1476 | ||
| Seq/Len: | 7.20 |
| SGBH
Paralog alert: 0.49 [within 20: 0.00] - ratio of genomes with paralogs Cluster includes: PYRF SGBH ULAD |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 199_N | 202_Q | 3.956 | 1.00 | |
| 23_T | 53_Q | 3.722 | 1.00 | |
| 51_R | 82_N | 3.58 | 1.00 | |
| 14_S | 17_A | 3.566 | 1.00 | |
| 6_L | 190_A | 3.045 | 1.00 | |
| 90_A | 94_T | 2.688 | 1.00 | |
| 202_Q | 206_D | 2.676 | 1.00 | |
| 197_A | 203_V | 2.667 | 1.00 | |
| 92_L | 96_E | 2.441 | 1.00 | |
| 201_A | 205_G | 2.321 | 1.00 | |
| 45_G | 48_K | 2.254 | 1.00 | |
| 157_K | 186_K | 2.063 | 1.00 | |
| 178_P | 210_Q | 1.991 | 1.00 | |
| 178_P | 182_D | 1.981 | 1.00 | |
| 15_L | 49_A | 1.964 | 1.00 | |
| 174_P | 193_A | 1.954 | 1.00 | |
| 95_V | 130_V | 1.93 | 1.00 | |
| 126_H | 161_D | 1.925 | 1.00 | |
| 19_Q | 49_A | 1.872 | 1.00 | |
| 185_V | 188_F | 1.861 | 1.00 | |
| 156_M | 167_S | 1.824 | 1.00 | |
| 92_L | 128_I | 1.787 | 1.00 | |
| 36_T | 40_L | 1.78 | 1.00 | |
| 150_E | 172_I | 1.765 | 1.00 | |
| 65_V | 76_A | 1.684 | 1.00 | |
| 157_K | 167_S | 1.634 | 1.00 | |
| 96_E | 100_A | 1.629 | 1.00 | |
| 12_H | 21_D | 1.615 | 1.00 | |
| 21_D | 25_L | 1.615 | 1.00 | |
| 7_Q | 31_I | 1.613 | 1.00 | |
| 122_A | 125_W | 1.583 | 1.00 | |
| 179_L | 182_D | 1.575 | 1.00 | |
| 28_S | 205_G | 1.562 | 1.00 | |
| 6_L | 204_A | 1.541 | 1.00 | |
| 169_T | 185_V | 1.517 | 0.99 | |
| 34_A | 50_L | 1.5 | 0.99 | |
| 38_L | 42_E | 1.468 | 0.99 | |
| 6_L | 211_I | 1.448 | 0.99 | |
| 202_Q | 205_G | 1.435 | 0.99 | |
| 181_K | 188_F | 1.428 | 0.99 | |
| 20_R | 24_L | 1.427 | 0.99 | |
| 174_P | 207_F | 1.402 | 0.99 | |
| 92_L | 127_R | 1.399 | 0.99 | |
| 179_L | 183_I | 1.378 | 0.99 | |
| 24_L | 199_N | 1.376 | 0.99 | |
| 42_E | 45_G | 1.372 | 0.99 | |
| 206_D | 209_A | 1.367 | 0.99 | |
| 30_D | 204_A | 1.366 | 0.99 | |
| 24_L | 200_P | 1.363 | 0.99 | |
| 154_A | 158_A | 1.359 | 0.98 | |
| 41_N | 75_Q | 1.348 | 0.98 | |
| 40_L | 65_V | 1.342 | 0.98 | |
| 10_L | 50_L | 1.321 | 0.98 | |
| 17_A | 20_R | 1.313 | 0.98 | |
| 15_L | 46_A | 1.309 | 0.98 | |
| 126_H | 160_S | 1.307 | 0.98 | |
| 47_V | 59_I | 1.295 | 0.98 | |
| 15_L | 42_E | 1.292 | 0.98 | |
| 49_A | 52_E | 1.278 | 0.98 | |
| 18_A | 38_L | 1.268 | 0.97 | |
| 156_M | 160_S | 1.268 | 0.97 | |
| 73_A | 84_M | 1.261 | 0.97 | |
| 9_A | 191_G | 1.257 | 0.97 | |
| 123_R | 127_R | 1.243 | 0.97 | |
| 32_V | 57_K | 1.243 | 0.97 | |
| 84_M | 102_A | 1.236 | 0.97 | |
| 93_A | 96_E | 1.234 | 0.97 | |
| 47_V | 79_A | 1.227 | 0.97 | |
| 8_L | 195_A | 1.223 | 0.97 | |
| 6_L | 208_H | 1.217 | 0.96 | |
| 89_A | 121_D | 1.209 | 0.96 | |
| 98_G | 101_M | 1.197 | 0.96 | |
| 103_Q | 106_G | 1.188 | 0.96 | |
| 108_E | 112_E | 1.18 | 0.95 | |
| 24_L | 201_A | 1.17 | 0.95 | |
| 38_L | 46_A | 1.154 | 0.95 | |
| 99_H | 103_Q | 1.152 | 0.95 | |
| 154_A | 183_I | 1.151 | 0.95 | |
| 153_L | 185_V | 1.147 | 0.94 | |
| 19_Q | 23_T | 1.142 | 0.94 | |
| 107_G | 110_Q | 1.125 | 0.94 | |
| 206_D | 210_Q | 1.118 | 0.93 | |
| 58_I | 82_N | 1.118 | 0.93 | |
| 205_G | 209_A | 1.105 | 0.93 | |
| 69_G | 94_T | 1.103 | 0.93 | |
| 72_L | 175_A | 1.088 | 0.92 | |
| 29_V | 204_A | 1.078 | 0.92 | |
| 48_K | 52_E | 1.071 | 0.91 | |
| 22_V | 32_V | 1.066 | 0.91 | |
| 88_C | 125_W | 1.064 | 0.91 | |
| 74_Q | 78_G | 1.06 | 0.91 | |
| 13_S | 17_A | 1.04 | 0.90 | |
| 31_I | 83_W | 1.035 | 0.89 | |
| 8_L | 29_V | 1.035 | 0.89 | |
| 25_L | 201_A | 1.033 | 0.89 | |
| 123_R | 159_L | 1.025 | 0.89 | |
| 22_V | 42_E | 1.016 | 0.88 | |
| 85_T | 95_V | 1.015 | 0.88 | |
| 31_I | 82_N | 1.014 | 0.88 | |
| 61_A | 81_A | 1.011 | 0.88 | |
| 203_V | 210_Q | 1.009 | 0.88 | |
| 31_I | 58_I | 1.009 | 0.88 | |
| 97_K | 100_A | 1.007 | 0.88 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3qw4B | 2 | 0.9409 | 100 | 0.347 | Contact Map | 0.467 |
| 3gdmA | 2 | 0.9136 | 100 | 0.358 | Contact Map | 0.533 |
| 3qw3A | 2 | 0.9318 | 100 | 0.358 | Contact Map | 0.501 |
| 2ffcA | 1 | 0.9409 | 100 | 0.384 | Contact Map | 0.38 |
| 4mjzA | 2 | 0.9409 | 100 | 0.393 | Contact Map | 0.52 |
| 3ldvA | 2 | 0.8909 | 100 | 0.409 | Contact Map | 0.772 |
| 3r89A | 2 | 0.9318 | 100 | 0.414 | Contact Map | 0.449 |
| 3tfxA | 2 | 0.9273 | 100 | 0.42 | Contact Map | 0.719 |
| 3tr2A | 2 | 0.9 | 100 | 0.421 | Contact Map | 0.745 |
| 1dbtA | 3 | 0.9091 | 100 | 0.423 | Contact Map | 0.833 |
Sequence Conservation (Image Generated using WebLogo v3)