| UniProt: | P0AF12 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11090 | ||
| Length: | 232 (228) | ||
| Sequences: | 2892 | ||
| Seq/Len: | 12.68 |
| MTNN
Paralog alert: 0.69 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: DEOD MTNN UDP |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 22_N | 37_Q | 3.434 | 1.00 | |
| 77_A | 195_I | 3.199 | 1.00 | |
| 63_L | 187_V | 2.819 | 1.00 | |
| 182_C | 189_F | 2.725 | 1.00 | |
| 52_K | 149_D | 2.681 | 1.00 | |
| 146_V | 168_A | 2.353 | 1.00 | |
| 122_D | 188_P | 2.322 | 1.00 | |
| 70_V | 188_P | 2.309 | 1.00 | |
| 90_V | 170_A | 2.288 | 1.00 | |
| 160_K | 164_N | 2.203 | 1.00 | |
| 4_G | 62_L | 2.203 | 1.00 | |
| 175_A | 191_V | 2.145 | 1.00 | |
| 127_A | 130_E | 2.124 | 1.00 | |
| 84_L | 141_V | 1.921 | 1.00 | |
| 157_G | 160_K | 1.909 | 1.00 | |
| 94_E | 120_K | 1.907 | 1.00 | |
| 94_E | 144_L | 1.9 | 1.00 | |
| 92_S | 145_I | 1.866 | 1.00 | |
| 126_I | 129_A | 1.846 | 1.00 | |
| 5_I | 16_L | 1.839 | 1.00 | |
| 93_D | 142_R | 1.805 | 1.00 | |
| 37_Q | 42_E | 1.789 | 1.00 | |
| 69_D | 187_V | 1.74 | 1.00 | |
| 77_A | 170_A | 1.728 | 1.00 | |
| 7_G | 13_V | 1.694 | 1.00 | |
| 61_L | 64_E | 1.687 | 1.00 | |
| 127_A | 131_A | 1.686 | 1.00 | |
| 60_T | 185_F | 1.68 | 1.00 | |
| 59_A | 71_I | 1.669 | 1.00 | |
| 98_H | 148_G | 1.657 | 1.00 | |
| 52_K | 177_A | 1.614 | 1.00 | |
| 53_V | 149_D | 1.594 | 1.00 | |
| 172_E | 175_A | 1.581 | 1.00 | |
| 60_T | 64_E | 1.561 | 1.00 | |
| 81_A | 169_I | 1.547 | 1.00 | |
| 90_V | 195_I | 1.525 | 1.00 | |
| 80_L | 171_V | 1.511 | 1.00 | |
| 130_E | 134_A | 1.501 | 1.00 | |
| 52_K | 147_S | 1.496 | 1.00 | |
| 24_Q | 35_T | 1.496 | 1.00 | |
| 170_A | 195_I | 1.485 | 1.00 | |
| 129_A | 190_V | 1.477 | 1.00 | |
| 63_L | 71_I | 1.458 | 1.00 | |
| 64_E | 185_F | 1.453 | 1.00 | |
| 126_I | 130_E | 1.445 | 1.00 | |
| 10_E | 47_K | 1.421 | 1.00 | |
| 85_K | 88_D | 1.411 | 1.00 | |
| 130_E | 142_R | 1.407 | 0.99 | |
| 90_V | 169_I | 1.405 | 0.99 | |
| 71_I | 187_V | 1.39 | 0.99 | |
| 3_I | 226_V | 1.378 | 0.99 | |
| 125_L | 190_V | 1.372 | 0.99 | |
| 27_S | 32_E | 1.37 | 0.99 | |
| 123_D | 126_I | 1.356 | 0.99 | |
| 14_T | 18_D | 1.341 | 0.99 | |
| 46_L | 58_G | 1.331 | 0.99 | |
| 154_G | 157_G | 1.315 | 0.99 | |
| 59_A | 178_I | 1.306 | 0.99 | |
| 94_E | 118_G | 1.297 | 0.99 | |
| 91_V | 140_A | 1.295 | 0.99 | |
| 77_A | 193_R | 1.289 | 0.99 | |
| 208_D | 211_L | 1.273 | 0.99 | |
| 128_A | 132_C | 1.271 | 0.99 | |
| 71_I | 182_C | 1.267 | 0.99 | |
| 55_A | 178_I | 1.266 | 0.99 | |
| 81_A | 84_L | 1.254 | 0.99 | |
| 129_A | 132_C | 1.253 | 0.99 | |
| 147_S | 175_A | 1.238 | 0.98 | |
| 113_P | 116_P | 1.23 | 0.98 | |
| 91_V | 221_M | 1.225 | 0.98 | |
| 123_D | 127_A | 1.221 | 0.98 | |
| 205_L | 208_D | 1.204 | 0.98 | |
| 145_I | 170_A | 1.201 | 0.98 | |
| 20_I | 45_L | 1.198 | 0.98 | |
| 159_A | 162_R | 1.19 | 0.98 | |
| 37_Q | 40_G | 1.187 | 0.98 | |
| 123_D | 130_E | 1.18 | 0.98 | |
| 91_V | 126_I | 1.167 | 0.97 | |
| 8_A | 73_N | 1.161 | 0.97 | |
| 173_M | 203_S | 1.161 | 0.97 | |
| 125_L | 129_A | 1.154 | 0.97 | |
| 95_A | 191_V | 1.153 | 0.97 | |
| 13_V | 34_Y | 1.147 | 0.97 | |
| 63_L | 68_P | 1.144 | 0.97 | |
| 112_L | 115_C | 1.139 | 0.97 | |
| 35_T | 44_A | 1.139 | 0.97 | |
| 20_I | 36_G | 1.132 | 0.97 | |
| 143_G | 169_I | 1.128 | 0.97 | |
| 73_N | 178_I | 1.125 | 0.97 | |
| 52_K | 99_D | 1.122 | 0.97 | |
| 79_G | 198_V | 1.122 | 0.97 | |
| 97_Y | 180_H | 1.102 | 0.96 | |
| 211_L | 214_A | 1.099 | 0.96 | |
| 36_G | 43_V | 1.092 | 0.96 | |
| 141_V | 169_I | 1.09 | 0.96 | |
| 13_V | 45_L | 1.087 | 0.96 | |
| 95_A | 179_A | 1.085 | 0.96 | |
| 79_G | 195_I | 1.084 | 0.96 | |
| 109_Y | 164_N | 1.079 | 0.95 | |
| 126_I | 142_R | 1.078 | 0.95 | |
| 39_N | 227_Q | 1.069 | 0.95 | |
| 127_A | 134_A | 1.067 | 0.95 | |
| 11_E | 209_E | 1.064 | 0.95 | |
| 105_F | 108_E | 1.063 | 0.95 | |
| 33_I | 44_A | 1.063 | 0.95 | |
| 126_I | 190_V | 1.063 | 0.95 | |
| 55_A | 177_A | 1.061 | 0.95 | |
| 24_Q | 42_E | 1.061 | 0.95 | |
| 224_S | 227_Q | 1.06 | 0.95 | |
| 26_I | 35_T | 1.044 | 0.94 | |
| 151_F | 173_M | 1.042 | 0.94 | |
| 51_G | 173_M | 1.039 | 0.94 | |
| 224_S | 228_K | 1.03 | 0.94 | |
| 95_A | 175_A | 1.029 | 0.94 | |
| 145_I | 193_R | 1.027 | 0.94 | |
| 159_A | 163_H | 1.025 | 0.93 | |
| 83_T | 141_V | 1.024 | 0.93 | |
| 179_A | 189_F | 1.018 | 0.93 | |
| 124_K | 127_A | 1.017 | 0.93 | |
| 128_A | 131_A | 1.014 | 0.93 | |
| 21_E | 37_Q | 1.009 | 0.93 | |
| 135_E | 228_K | 1.004 | 0.93 | |
| 19_K | 223_E | 1.002 | 0.92 | |
| 15_L | 219_S | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3dp9A | 2 | 0.9914 | 100 | 0.167 | Contact Map | 0.827 |
| 1zosA | 6 | 0.9914 | 100 | 0.169 | Contact Map | 0.809 |
| 3bl6A | 1 | 0.9871 | 100 | 0.169 | Contact Map | 0.786 |
| 4f1wA | 2 | 1 | 100 | 0.177 | Contact Map | 0.855 |
| 4kn5A | 2 | 0.9914 | 100 | 0.181 | Contact Map | 0.812 |
| 3nm6B | 1 | 0.9828 | 100 | 0.182 | Contact Map | 0.788 |
| 4l0mA | 1 | 0.9871 | 100 | 0.183 | Contact Map | 0.79 |
| 4g41A | 2 | 0.9957 | 100 | 0.184 | Contact Map | 0.825 |
| 4josA | 2 | 0.9784 | 100 | 0.186 | Contact Map | 0.836 |
| 3eeiA | 2 | 0.9871 | 100 | 0.186 | Contact Map | 0.814 |
Sequence Conservation (Image Generated using WebLogo v3)