| UniProt: | P0AEU0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12124 | ||
| Length: | 260 (235) | ||
| Sequences: | 10332 | ||
| Seq/Len: | 43.97 |
| HISJ
Paralog alert: 0.90 [within 20: 0.40] - ratio of genomes with paralogs Cluster includes: ARGT ARTI ARTJ FLIY GLNH GLTI HISJ YHDW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 137_G | 177_I | 3.822 | 1.00 | |
| 31_G | 86_I | 3.477 | 1.00 | |
| 27_N | 68_T | 3.303 | 1.00 | |
| 62_R | 238_E | 3.303 | 1.00 | |
| 107_D | 237_A | 2.684 | 1.00 | |
| 162_Y | 171_D | 2.465 | 1.00 | |
| 97_E | 100_Q | 2.461 | 1.00 | |
| 29_R | 68_T | 2.452 | 1.00 | |
| 95_I | 218_G | 2.407 | 1.00 | |
| 244_T | 247_K | 2.344 | 1.00 | |
| 27_N | 66_Q | 2.306 | 1.00 | |
| 95_I | 100_Q | 2.285 | 1.00 | |
| 229_R | 233_N | 2.264 | 1.00 | |
| 246_E | 250_K | 2.249 | 1.00 | |
| 80_S | 86_I | 2.18 | 1.00 | |
| 29_R | 70_V | 2.147 | 1.00 | |
| 145_E | 161_S | 2.13 | 1.00 | |
| 103_I | 220_G | 2.108 | 1.00 | |
| 164_G | 167_N | 2.091 | 1.00 | |
| 237_A | 241_A | 2.088 | 1.00 | |
| 60_C | 67_C | 2.071 | 1.00 | |
| 145_E | 149_N | 2.048 | 1.00 | |
| 58_E | 61_K | 2.037 | 1.00 | |
| 221_L | 229_R | 2.026 | 1.00 | |
| 127_T | 130_S | 2.011 | 1.00 | |
| 43_N | 49_V | 1.973 | 1.00 | |
| 221_L | 232_L | 1.945 | 1.00 | |
| 82_K | 102_E | 1.94 | 1.00 | |
| 135_R | 160_V | 1.935 | 1.00 | |
| 104_A | 229_R | 1.928 | 1.00 | |
| 135_R | 158_E | 1.917 | 1.00 | |
| 107_D | 233_N | 1.905 | 1.00 | |
| 58_E | 244_T | 1.874 | 1.00 | |
| 126_P | 130_S | 1.841 | 1.00 | |
| 54_D | 251_K | 1.822 | 1.00 | |
| 182_Q | 187_A | 1.787 | 1.00 | |
| 222_R | 225_D | 1.748 | 1.00 | |
| 58_E | 239_M | 1.745 | 1.00 | |
| 62_R | 235_A | 1.74 | 1.00 | |
| 58_E | 62_R | 1.728 | 1.00 | |
| 90_M | 219_M | 1.711 | 1.00 | |
| 62_R | 242_D | 1.691 | 1.00 | |
| 54_D | 252_Y | 1.637 | 1.00 | |
| 230_E | 234_K | 1.634 | 1.00 | |
| 226_N | 230_E | 1.626 | 1.00 | |
| 104_A | 224_E | 1.623 | 1.00 | |
| 106_T | 233_N | 1.621 | 1.00 | |
| 43_N | 47_E | 1.612 | 1.00 | |
| 117_V | 187_A | 1.6 | 1.00 | |
| 168_I | 180_A | 1.557 | 1.00 | |
| 30_I | 56_A | 1.489 | 1.00 | |
| 134_K | 178_D | 1.483 | 1.00 | |
| 80_S | 85_K | 1.46 | 1.00 | |
| 119_A | 122_S | 1.438 | 1.00 | |
| 171_D | 176_R | 1.385 | 0.99 | |
| 30_I | 88_A | 1.38 | 0.99 | |
| 119_A | 175_G | 1.376 | 0.99 | |
| 172_L | 177_I | 1.374 | 0.99 | |
| 136_V | 179_A | 1.367 | 0.99 | |
| 231_A | 234_K | 1.361 | 0.99 | |
| 106_T | 232_L | 1.36 | 0.99 | |
| 41_S | 49_V | 1.33 | 0.99 | |
| 98_K | 101_Q | 1.329 | 0.99 | |
| 63_I | 235_A | 1.323 | 0.99 | |
| 184_E | 188_S | 1.322 | 0.99 | |
| 57_K | 69_F | 1.32 | 0.99 | |
| 140_Q | 163_Q | 1.32 | 0.99 | |
| 89_I | 93_L | 1.286 | 0.99 | |
| 234_K | 238_E | 1.283 | 0.99 | |
| 146_T | 150_E | 1.278 | 0.99 | |
| 104_A | 226_N | 1.277 | 0.99 | |
| 163_Q | 167_N | 1.277 | 0.99 | |
| 78_I | 103_I | 1.271 | 0.99 | |
| 121_N | 201_K | 1.262 | 0.99 | |
| 120_K | 201_K | 1.262 | 0.99 | |
| 52_D | 109_L | 1.257 | 0.99 | |
| 231_A | 235_A | 1.252 | 0.99 | |
| 26_Q | 65_T | 1.237 | 0.98 | |
| 51_F | 248_L | 1.234 | 0.98 | |
| 116_L | 179_A | 1.232 | 0.98 | |
| 59_L | 235_A | 1.232 | 0.98 | |
| 77_L | 89_I | 1.228 | 0.98 | |
| 129_E | 132_K | 1.228 | 0.98 | |
| 244_T | 248_L | 1.227 | 0.98 | |
| 47_E | 57_K | 1.227 | 0.98 | |
| 84_K | 222_R | 1.223 | 0.98 | |
| 88_A | 232_L | 1.209 | 0.98 | |
| 72_N | 80_S | 1.206 | 0.98 | |
| 135_R | 178_D | 1.204 | 0.98 | |
| 137_G | 162_Y | 1.199 | 0.98 | |
| 120_K | 199_D | 1.199 | 0.98 | |
| 42_K | 71_E | 1.193 | 0.98 | |
| 172_L | 180_A | 1.19 | 0.98 | |
| 118_V | 203_G | 1.184 | 0.98 | |
| 88_A | 221_L | 1.182 | 0.98 | |
| 139_L | 142_T | 1.18 | 0.98 | |
| 238_E | 242_D | 1.178 | 0.98 | |
| 51_F | 249_A | 1.177 | 0.98 | |
| 73_P | 76_A | 1.175 | 0.98 | |
| 171_D | 177_I | 1.173 | 0.98 | |
| 235_A | 238_E | 1.166 | 0.97 | |
| 30_I | 67_C | 1.162 | 0.97 | |
| 115_R | 202_F | 1.157 | 0.97 | |
| 235_A | 239_M | 1.146 | 0.97 | |
| 132_K | 156_G | 1.128 | 0.97 | |
| 147_F | 151_H | 1.127 | 0.97 | |
| 113_D | 184_E | 1.124 | 0.97 | |
| 162_Y | 168_I | 1.117 | 0.96 | |
| 53_I | 57_K | 1.116 | 0.96 | |
| 104_A | 223_K | 1.113 | 0.96 | |
| 55_L | 239_M | 1.113 | 0.96 | |
| 54_D | 57_K | 1.104 | 0.96 | |
| 93_L | 220_G | 1.103 | 0.96 | |
| 62_R | 239_M | 1.101 | 0.96 | |
| 240_R | 245_Y | 1.096 | 0.96 | |
| 56_A | 90_M | 1.093 | 0.96 | |
| 79_P | 82_K | 1.091 | 0.96 | |
| 56_A | 69_F | 1.078 | 0.95 | |
| 115_R | 184_E | 1.076 | 0.95 | |
| 51_F | 253_F | 1.075 | 0.95 | |
| 149_N | 161_S | 1.065 | 0.95 | |
| 172_L | 200_Y | 1.065 | 0.95 | |
| 137_G | 168_I | 1.053 | 0.95 | |
| 125_Q | 130_S | 1.05 | 0.94 | |
| 57_K | 61_K | 1.048 | 0.94 | |
| 239_M | 244_T | 1.044 | 0.94 | |
| 170_S | 173_T | 1.034 | 0.94 | |
| 55_L | 245_Y | 1.032 | 0.94 | |
| 247_K | 250_K | 1.023 | 0.93 | |
| 114_S | 144_Q | 1.021 | 0.93 | |
| 39_F | 110_Y | 1.017 | 0.93 | |
| 48_L | 53_I | 1.011 | 0.93 | |
| 96_T | 99_R | 1.003 | 0.93 | |
| 118_V | 179_A | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ylnA | 1 | 0.9577 | 100 | 0.237 | Contact Map | 0.824 |
| 3hv1A | 2 | 0.9538 | 100 | 0.238 | Contact Map | 0.8 |
| 3k4uA | 6 | 0.8885 | 100 | 0.248 | Contact Map | 0.842 |
| 1lstA | 1 | 0.9154 | 100 | 0.249 | Contact Map | 0.829 |
| 3vv5A | 2 | 0.9577 | 100 | 0.252 | Contact Map | 0.884 |
| 2vhaA | 2 | 0.9385 | 100 | 0.253 | Contact Map | 0.806 |
| 2ieeA | 2 | 0.9423 | 100 | 0.255 | Contact Map | 0.834 |
| 3kbrA | 1 | 0.9 | 100 | 0.259 | Contact Map | 0.814 |
| 3h7mA | 1 | 0.9 | 100 | 0.26 | Contact Map | 0.804 |
| 1xt8A | 2 | 0.9615 | 100 | 0.261 | Contact Map | 0.865 |
Sequence Conservation (Image Generated using WebLogo v3)