| UniProt: | P0ACJ8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10164 | ||
| Length: | 210 (203) | ||
| Sequences: | 6173 | ||
| Seq/Len: | 30.41 |
| CRP
Paralog alert: 0.75 [within 20: 0.09] - ratio of genomes with paralogs Cluster includes: CRP FNR YEIL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 39_T | 97_E | 3.219 | 1.00 | |
| 25_P | 28_S | 2.782 | 1.00 | |
| 23_K | 94_E | 2.673 | 1.00 | |
| 45_K | 94_E | 2.623 | 1.00 | |
| 51_L | 88_R | 2.519 | 1.00 | |
| 145_A | 191_L | 2.455 | 1.00 | |
| 105_Q | 109_V | 2.415 | 1.00 | |
| 140_V | 179_C | 2.333 | 1.00 | |
| 44_V | 96_A | 2.301 | 1.00 | |
| 198_S | 205_V | 2.194 | 1.00 | |
| 33_Q | 86_W | 2.185 | 1.00 | |
| 50_V | 87_V | 2.129 | 1.00 | |
| 170_R | 185_G | 2.127 | 1.00 | |
| 141_T | 190_M | 2.12 | 1.00 | |
| 8_T | 11_T | 2.107 | 1.00 | |
| 198_S | 207_Y | 2.107 | 1.00 | |
| 139_D | 142_G | 2.053 | 1.00 | |
| 99_S | 102_K | 2.045 | 1.00 | |
| 144_I | 187_I | 1.965 | 1.00 | |
| 31_I | 87_V | 1.949 | 1.00 | |
| 21_I | 94_E | 1.944 | 1.00 | |
| 25_P | 92_A | 1.932 | 1.00 | |
| 48_V | 87_V | 1.931 | 1.00 | |
| 51_L | 86_W | 1.911 | 1.00 | |
| 24_Y | 30_L | 1.898 | 1.00 | |
| 32_H | 35_E | 1.891 | 1.00 | |
| 89_A | 93_C | 1.881 | 1.00 | |
| 22_H | 97_E | 1.836 | 1.00 | |
| 24_Y | 95_V | 1.788 | 1.00 | |
| 48_V | 93_C | 1.77 | 1.00 | |
| 125_L | 128_T | 1.75 | 1.00 | |
| 23_K | 92_A | 1.75 | 1.00 | |
| 100_Y | 104_R | 1.748 | 1.00 | |
| 49_A | 61_I | 1.748 | 1.00 | |
| 33_Q | 52_I | 1.726 | 1.00 | |
| 11_T | 112_D | 1.682 | 1.00 | |
| 28_S | 89_A | 1.662 | 1.00 | |
| 29_T | 88_R | 1.64 | 1.00 | |
| 47_S | 91_T | 1.613 | 1.00 | |
| 59_E | 175_Q | 1.613 | 1.00 | |
| 49_A | 88_R | 1.611 | 1.00 | |
| 29_T | 32_H | 1.571 | 1.00 | |
| 11_T | 110_N | 1.554 | 1.00 | |
| 140_V | 183_T | 1.54 | 1.00 | |
| 179_C | 184_V | 1.51 | 1.00 | |
| 152_A | 206_V | 1.5 | 1.00 | |
| 14_W | 109_V | 1.497 | 1.00 | |
| 108_Q | 115_M | 1.479 | 1.00 | |
| 171_Q | 181_R | 1.473 | 1.00 | |
| 128_T | 132_V | 1.465 | 1.00 | |
| 26_S | 92_A | 1.463 | 1.00 | |
| 190_M | 194_Q | 1.443 | 1.00 | |
| 26_S | 91_T | 1.436 | 1.00 | |
| 145_A | 149_L | 1.428 | 1.00 | |
| 138_L | 146_Q | 1.427 | 1.00 | |
| 141_T | 194_Q | 1.415 | 1.00 | |
| 49_A | 59_E | 1.383 | 0.99 | |
| 189_K | 193_D | 1.381 | 0.99 | |
| 102_K | 105_Q | 1.379 | 0.99 | |
| 43_I | 65_L | 1.372 | 0.99 | |
| 171_Q | 175_Q | 1.368 | 0.99 | |
| 134_N | 146_Q | 1.364 | 0.99 | |
| 65_L | 69_D | 1.36 | 0.99 | |
| 134_N | 138_L | 1.343 | 0.99 | |
| 165_Q | 203_T | 1.341 | 0.99 | |
| 29_T | 86_W | 1.338 | 0.99 | |
| 18_H | 102_K | 1.336 | 0.99 | |
| 64_Y | 176_I | 1.327 | 0.99 | |
| 43_I | 48_V | 1.325 | 0.99 | |
| 170_R | 181_R | 1.321 | 0.99 | |
| 191_L | 196_L | 1.313 | 0.99 | |
| 43_I | 93_C | 1.302 | 0.99 | |
| 118_S | 121_M | 1.3 | 0.99 | |
| 192_E | 199_A | 1.292 | 0.99 | |
| 114_L | 118_S | 1.284 | 0.99 | |
| 44_V | 94_E | 1.284 | 0.99 | |
| 54_D | 58_K | 1.282 | 0.99 | |
| 9_D | 13_E | 1.264 | 0.99 | |
| 19_C | 98_I | 1.249 | 0.99 | |
| 30_L | 48_V | 1.243 | 0.98 | |
| 192_E | 198_S | 1.23 | 0.98 | |
| 41_Y | 97_E | 1.224 | 0.98 | |
| 30_L | 41_Y | 1.211 | 0.98 | |
| 21_I | 44_V | 1.208 | 0.98 | |
| 147_T | 177_V | 1.2 | 0.98 | |
| 79_E | 126_Q | 1.2 | 0.98 | |
| 73_E | 124_R | 1.198 | 0.98 | |
| 14_W | 110_N | 1.18 | 0.98 | |
| 37_A | 83_R | 1.164 | 0.97 | |
| 103_F | 107_I | 1.158 | 0.97 | |
| 144_I | 177_V | 1.107 | 0.96 | |
| 21_I | 96_A | 1.101 | 0.96 | |
| 49_A | 172_E | 1.1 | 0.96 | |
| 180_S | 183_T | 1.09 | 0.96 | |
| 189_K | 192_E | 1.088 | 0.96 | |
| 147_T | 173_I | 1.086 | 0.96 | |
| 50_V | 65_L | 1.085 | 0.96 | |
| 13_E | 17_S | 1.077 | 0.95 | |
| 19_C | 96_A | 1.074 | 0.95 | |
| 27_K | 88_R | 1.072 | 0.95 | |
| 14_W | 17_S | 1.068 | 0.95 | |
| 22_H | 95_V | 1.065 | 0.95 | |
| 47_S | 66_N | 1.046 | 0.94 | |
| 177_V | 184_V | 1.043 | 0.94 | |
| 7_Q | 11_T | 1.032 | 0.94 | |
| 182_E | 186_R | 1.031 | 0.94 | |
| 20_H | 97_E | 1.02 | 0.93 | |
| 40_L | 103_F | 1.015 | 0.93 | |
| 105_Q | 108_Q | 1.013 | 0.93 | |
| 24_Y | 89_A | 1.012 | 0.93 | |
| 45_K | 67_Q | 1.011 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3rypA | 2 | 0.9952 | 100 | 0.135 | Contact Map | 0.855 |
| 4hzfA | 2 | 0.9952 | 100 | 0.152 | Contact Map | 0.868 |
| 3iwzA | 4 | 0.9952 | 100 | 0.152 | Contact Map | 0.861 |
| 2gauA | 1 | 0.9952 | 100 | 0.157 | Contact Map | 0.79 |
| 3d0sA | 2 | 0.9952 | 100 | 0.161 | Contact Map | 0.803 |
| 2oz6A | 1 | 0.9667 | 100 | 0.164 | Contact Map | 0.837 |
| 3e97A | 1 | 0.9857 | 100 | 0.167 | Contact Map | 0.697 |
| 3dkwA | 10 | 0.9857 | 100 | 0.167 | Contact Map | 0.831 |
| 3dv8A | 1 | 0.9667 | 100 | 0.167 | Contact Map | 0.775 |
| 3fx3A | 2 | 0.9762 | 100 | 0.171 | Contact Map | 0.772 |
Sequence Conservation (Image Generated using WebLogo v3)