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OPENSEQ.org

YEDF - UPF0033 protein YedF
UniProt: P0AA31 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11661
Length: 77 (72)
Sequences: 1294
Seq/Len: 17.97

YEDF
Paralog alert: 0.51 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: TUSA YEDF YEED
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
60_T 76_Q 3.35 1.00
32_K 35_E 2.619 1.00
7_D 35_E 2.606 1.00
13_V 70_T 2.433 1.00
38_E 72_R 2.197 1.00
13_V 40_V 2.077 1.00
9_R 38_E 1.99 1.00
36_I 62_L 1.787 1.00
31_L 37_L 1.765 1.00
24_T 50_I 1.603 1.00
43_C 49_N 1.582 1.00
54_A 75_I 1.541 1.00
36_I 74_L 1.469 1.00
8_Y 27_A 1.432 1.00
65_Q 72_R 1.415 1.00
12_M 41_S 1.374 0.99
13_V 42_D 1.356 0.99
15_E 19_Y 1.328 0.99
66_Q 69_P 1.327 0.99
10_L 37_L 1.318 0.99
39_V 50_I 1.314 0.99
24_T 37_L 1.307 0.99
24_T 39_V 1.293 0.99
19_Y 23_A 1.278 0.99
14_G 42_D 1.274 0.99
40_V 72_R 1.251 0.99
27_A 30_Q 1.223 0.98
21_A 53_D 1.171 0.98
47_I 64_I 1.126 0.97
54_A 61_V 1.119 0.96
25_L 29_P 1.118 0.96
46_S 73_Y 1.114 0.96
36_I 76_Q 1.091 0.96
38_E 74_L 1.07 0.95
42_D 45_Q 1.06 0.95
15_E 23_A 1.05 0.94
9_R 40_V 1.041 0.94
22_V 53_D 1.025 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1je3A1199.90.075Contact Map0.408
1jdqA1199.80.085Contact Map0.401
1pavA10.98799.80.12Contact Map0.641
3lvjC20.97499.80.137Contact Map0.839
3hz7A10.922199.80.139Contact Map0.71
2lxrA10.883199.70.244Contact Map0.447
1okgA10.7403980.609Contact Map0.19
2l3mA10.792262.30.827Contact Map0.173
2qifA20.766251.40.838Contact Map0.275
1yg0A10.740351.20.838Contact Map0.156

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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