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OPENSEQ.org

TUSA - Sulfurtransferase TusA
UniProt: P0A890 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12216
Length: 81 (74)
Sequences: 1302
Seq/Len: 17.59

TUSA
Paralog alert: 0.51 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: TUSA YEDF YEED
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
62_E 78_R 3.255 1.00
34_Q 37_E 2.712 1.00
9_D 37_E 2.634 1.00
15_L 72_P 2.395 1.00
40_L 74_R 2.202 1.00
15_L 42_I 2.135 1.00
11_T 40_L 1.989 1.00
38_T 64_V 1.867 1.00
33_M 39_L 1.753 1.00
26_V 52_I 1.637 1.00
45_D 51_D 1.562 1.00
56_C 77_I 1.547 1.00
12_L 39_L 1.433 1.00
67_E 74_R 1.425 1.00
15_L 44_D 1.415 1.00
14_A 43_A 1.399 0.99
38_T 76_L 1.394 0.99
68_T 71_L 1.363 0.99
26_V 39_L 1.336 0.99
10_H 29_T 1.321 0.99
41_I 52_I 1.318 0.99
42_I 74_R 1.318 0.99
17_L 21_E 1.316 0.99
26_V 41_I 1.293 0.99
21_E 25_M 1.291 0.99
16_G 44_D 1.288 0.99
35_P 80_G 1.262 0.99
23_V 55_F 1.243 0.98
29_T 32_N 1.217 0.98
56_C 63_L 1.205 0.98
38_T 78_R 1.185 0.98
27_R 31_R 1.123 0.97
44_D 47_A 1.096 0.96
40_L 76_L 1.095 0.96
49_T 66_K 1.09 0.96
48_T 75_Y 1.072 0.95
17_L 25_M 1.05 0.94
24_M 27_R 1.047 0.94
21_E 24_M 1.01 0.93
47_A 54_G 1.01 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3lvjC2199.80.13Contact Map0.831
1je3A10.950699.80.131Contact Map0.4
1jdqA10.96399.80.138Contact Map0.418
3hz7A10.901299.80.161Contact Map0.705
1pavA10.96399.80.17Contact Map0.632
2lxrA10.864299.70.27Contact Map0.449
1okgA10.7407980.629Contact Map0.216
1yjrA10.802553.70.843Contact Map0.286
1cc8A10.8025530.843Contact Map0.285
2l3mA10.753147.30.849Contact Map0.23

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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