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OPENSEQ.org

ISPE - KPRS
UniProt: P62615 - P0A717
Length: 598
Sequences: 576
Seq/Len: 0.98
I_Prob: 0.04

ISPE - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Paralog alert: 0.56 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: ISPE KHSE
KPRS - Ribose-phosphate pyrophosphokinase
Paralog alert: 0.27 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: KPRS
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
8_P 232_A 1.57 0.04
113_T 188_D 1.45 0.03
65_N 299_A 1.31 0.02
185_F 216_C 1.27 0.02
276_S 88_V 1.21 0.01
276_S 260_N 1.20 0.01
232_Y 55_I 1.18 0.01
145_F 106_V 1.13 0.01
244_V 58_S 1.10 0.01
211_C 260_N 1.07 0.01
215_A 202_S 1.07 0.01
210_D 214_R 1.04 0.01
72_R 74_V 1.03 0.01
172_V 210_D 1.01 0.01
17_I 11_A 1.01 0.01
173_A 119_S 1.00 0.01
61_E 109_T 1.00 0.01
35_L 140_D 0.99 0.01
276_S 128_V 0.98 0.01
142_V 48_V 0.97 0.01
276_S 146_V 0.96 0.01
11_L 199_A 0.96 0.01
117_A 26_S 0.96 0.01
145_F 182_K 0.95 0.01
270_A 232_A 0.95 0.01
246_A 180_I 0.93 0.01
92_I 233_A 0.93 0.01
124_C 58_S 0.93 0.01
194_T 112_V 0.92 0.01
211_C 128_V 0.91 0.01
51_I 111_K 0.90 0.01
210_D 115_D 0.90 0.01
122_W 219_V 0.89 0.01
150_A 266_I 0.89 0.01
39_D 7_F 0.89 0.01
200_E 40_V 0.88 0.01
242_A 92_F 0.88 0.01
178_S 273_D 0.88 0.01
109_S 302_R 0.87 0.01
130_E 212_A 0.87 0.01
94_I 259_N 0.86 0.01
94_I 171_I 0.86 0.01
101_G 72_V 0.85 0.01
75_M 219_V 0.85 0.01
240_T 260_N 0.85 0.01
252_S 199_A 0.85 0.01
213_V 286_N 0.84 0.01
114_V 214_R 0.84 0.01
143_P 42_V 0.84 0.01
22_A 279_D 0.84 0.01
135_G 278_S 0.84 0.00
94_I 234_E 0.84 0.00
30_T 84_R 0.84 0.00
8_P 64_N 0.84 0.00
31_L 192_I 0.84 0.00
105_G 47_N 0.83 0.00
35_L 95_A 0.82 0.00
65_N 78_R 0.82 0.00
39_D 127_T 0.82 0.00
160_L 252_I 0.82 0.00
66_L 152_L 0.82 0.00
69_R 288_R 0.82 0.00
242_A 145_N 0.81 0.00
163_V 145_N 0.81 0.00
223_D 123_D 0.81 0.00
156_V 43_Q 0.81 0.00
152_F 56_I 0.81 0.00
129_D 214_R 0.81 0.00
30_T 115_D 0.81 0.00
136_L 8_A 0.80 0.00
160_L 58_S 0.80 0.00
188_P 145_N 0.80 0.00
118_L 60_C 0.79 0.00
28_L 63_T 0.79 0.00
254_A 230_C 0.79 0.00
177_V 303_I 0.79 0.00
43_I 180_I 0.79 0.00
276_S 219_V 0.79 0.00
116_V 214_R 0.79 0.00
65_N 88_V 0.79 0.00
105_G 101_V 0.78 0.00
32_F 133_E 0.78 0.00
253_E 163_N 0.78 0.00
9_A 7_F 0.78 0.00
53_L 163_N 0.78 0.00
134_M 166_V 0.78 0.00
150_A 204_V 0.78 0.00
191_P 223_I 0.78 0.00
98_L 206_H 0.78 0.00
240_T 201_V 0.78 0.00
52_R 44_I 0.77 0.00
127_S 212_A 0.77 0.00
146_V 210_D 0.77 0.00
17_I 249_T 0.77 0.00
248_F 19_I 0.76 0.00
240_T 78_R 0.76 0.00
105_G 106_V 0.76 0.00
41_I 127_T 0.76 0.00
11_L 151_I 0.76 0.00
39_D 5_K 0.76 0.00
51_I 303_I 0.76 0.00
145_F 47_N 0.76 0.00
66_L 110_A 0.76 0.00
131_L 64_N 0.75 0.00
138_L 267_D 0.75 0.00
261_A 251_P 0.75 0.00
101_G 106_V 0.75 0.00
250_T 19_I 0.75 0.00
53_L 40_V 0.75 0.00
7_S 101_V 0.75 0.00
149_H 293_S 0.75 0.00
194_T 120_V 0.75 0.00
11_L 206_H 0.75 0.00
71_A 233_A 0.74 0.00
184_I 304_S 0.74 0.00
17_I 58_S 0.74 0.00
105_G 143_V 0.74 0.00
257_V 230_C 0.74 0.00
161_T 285_P 0.74 0.00
100_M 8_A 0.74 0.00
122_W 175_V 0.74 0.00
109_S 246_A 0.74 0.00
161_T 40_V 0.74 0.00
97_R 166_V 0.74 0.00
276_S 78_R 0.74 0.00
247_E 100_R 0.74 0.00
70_A 249_T 0.74 0.00
122_W 61_A 0.74 0.00
32_F 103_S 0.74 0.00
172_V 214_R 0.73 0.00
274_N 260_N 0.73 0.00
243_C 46_E 0.73 0.00
165_P 296_L 0.73 0.00
5_W 227_G 0.73 0.00
55_T 8_A 0.73 0.00
149_H 274_T 0.73 0.00
138_L 42_V 0.73 0.00
203_L 48_V 0.73 0.00
275_L 300_I 0.73 0.00
230_L 5_K 0.73 0.00
113_T 155_D 0.73 0.00
101_G 273_D 0.73 0.00
19_G 53_I 0.73 0.00
161_T 242_K 0.73 0.00
154_E 48_V 0.73 0.00
177_V 218_L 0.73 0.00
176_G 151_I 0.73 0.00
63_E 61_A 0.72 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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