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OPENSEQ.org

COBC - COBS
UniProt: P52086 - P36561
Length: 450
Sequences: 454
Seq/Len: 1.03
I_Prob: 0.05

COBC - Alpha-ribazole phosphatase
Paralog alert: 0.82 [within 20: 0.08] - ratio of genomes with paralogs
Cluster includes: COBC GPMA GPMB
COBS - Cobalamin synthase
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: COBS
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
14_N 93_S 1.56 0.05
28_T 169_G 1.32 0.03
20_S 160_H 1.14 0.01
19_Y 81_L 1.12 0.01
170_H 122_L 1.10 0.01
4_W 90_G 1.09 0.01
14_N 95_R 1.07 0.01
150_Q 239_E 1.07 0.01
144_I 111_T 1.07 0.01
106_W 12_I 1.06 0.01
19_Y 93_S 1.06 0.01
110_W 233_A 1.05 0.01
61_T 95_R 1.05 0.01
3_L 183_V 1.02 0.01
169_W 93_S 1.01 0.01
79_L 164_R 1.00 0.01
19_Y 146_C 1.00 0.01
161_I 5_F 0.99 0.01
165_A 9_L 0.99 0.01
95_L 116_A 0.98 0.01
128_V 22_S 0.98 0.01
169_W 95_R 0.98 0.01
146_V 13_T 0.98 0.01
39_H 90_G 0.98 0.01
82_M 68_S 0.97 0.01
92_H 231_L 0.97 0.01
151_G 77_G 0.97 0.01
25_T 231_L 0.96 0.01
160_L 126_L 0.96 0.01
61_T 93_S 0.96 0.01
11_T 224_G 0.95 0.01
169_W 223_L 0.95 0.01
5_L 101_L 0.95 0.01
42_L 13_T 0.95 0.01
153_L 124_K 0.95 0.01
82_M 69_V 0.95 0.01
174_D 223_L 0.95 0.01
26_P 13_T 0.94 0.01
11_T 93_S 0.94 0.01
89_M 88_C 0.93 0.01
162_G 163_A 0.92 0.01
52_C 6_W 0.92 0.01
169_W 10_S 0.92 0.01
190_L 43_L 0.92 0.01
162_G 158_Y 0.92 0.01
61_T 226_Q 0.92 0.01
77_P 143_A 0.91 0.01
164_P 164_R 0.91 0.01
29_A 221_R 0.90 0.01
19_Y 235_I 0.90 0.01
39_H 65_A 0.88 0.01
116_T 125_I 0.88 0.01
121_F 163_A 0.87 0.01
106_W 21_W 0.87 0.01
4_W 88_C 0.87 0.01
88_E 111_T 0.87 0.01
176_G 107_S 0.87 0.01
87_W 94_A 0.87 0.01
24_P 77_G 0.86 0.01
14_N 92_F 0.86 0.01
145_L 76_T 0.86 0.01
72_P 62_P 0.86 0.01
88_E 167_G 0.86 0.01
11_T 95_R 0.85 0.01
34_Q 15_L 0.85 0.01
150_Q 8_M 0.85 0.01
145_L 42_L 0.85 0.01
169_W 11_F 0.85 0.01
178_W 111_T 0.85 0.01
28_T 156_L 0.85 0.01
146_V 28_E 0.85 0.01
144_I 119_F 0.85 0.01
94_D 202_V 0.84 0.01
131_F 7_A 0.84 0.01
89_M 175_K 0.84 0.01
31_G 167_G 0.84 0.01
128_V 91_V 0.83 0.01
142_Q 148_V 0.83 0.01
150_Q 146_C 0.83 0.01
74_Q 183_V 0.83 0.01
157_I 222_T 0.83 0.01
37_N 224_G 0.82 0.01
115_P 153_A 0.82 0.01
95_L 6_W 0.82 0.01
14_N 78_G 0.82 0.01
25_T 126_L 0.82 0.01
131_F 144_A 0.81 0.01
70_Q 50_L 0.81 0.01
18_L 85_A 0.81 0.01
117_N 244_L 0.81 0.01
73_V 195_L 0.81 0.01
59_Q 245_A 0.81 0.01
87_W 10_S 0.80 0.01
174_D 43_L 0.80 0.01
154_S 120_V 0.80 0.01
72_P 182_C 0.80 0.01
145_L 186_G 0.80 0.01
20_S 12_I 0.80 0.01
124_F 203_A 0.80 0.01
171_F 90_G 0.80 0.01
146_V 206_V 0.79 0.01
65_V 125_I 0.79 0.01
50_V 134_R 0.79 0.01
141_Y 209_M 0.79 0.01
146_V 195_L 0.79 0.01
87_W 85_A 0.79 0.01
48_D 162_Y 0.79 0.01
47_F 90_G 0.79 0.00
84_F 14_R 0.78 0.00
166_E 238_G 0.78 0.00
11_T 146_C 0.78 0.00
10_E 154_A 0.78 0.00
27_L 73_V 0.78 0.00
18_L 78_G 0.78 0.00
132_I 88_C 0.78 0.00
166_E 15_L 0.77 0.00
55_L 91_V 0.77 0.00
154_S 33_G 0.77 0.00
103_Y 94_A 0.77 0.00
122_Q 46_A 0.77 0.00
117_N 210_V 0.77 0.00
24_P 239_E 0.77 0.00
153_L 94_A 0.77 0.00
154_S 67_F 0.77 0.00
120_G 39_L 0.77 0.00
86_D 237_L 0.77 0.00
70_Q 70_L 0.76 0.00
162_G 223_L 0.76 0.00
181_I 67_F 0.76 0.00
166_E 221_R 0.76 0.00
54_E 235_I 0.76 0.00
79_L 214_I 0.76 0.00
111_Q 69_V 0.76 0.00
84_F 103_I 0.76 0.00
130_R 190_I 0.76 0.00
101_E 46_A 0.76 0.00
78_E 221_R 0.76 0.00
1_M 222_T 0.75 0.00
70_Q 165_E 0.75 0.00
92_H 9_L 0.75 0.00
175_Q 40_I 0.75 0.00
105_A 40_I 0.75 0.00
95_L 218_L 0.75 0.00
59_Q 163_A 0.75 0.00
54_E 146_C 0.75 0.00
124_F 151_G 0.75 0.00
133_A 128_L 0.75 0.00
71_L 75_M 0.75 0.00
153_L 84_L 0.75 0.00
55_L 90_G 0.75 0.00
115_P 233_A 0.75 0.00
31_G 149_S 0.75 0.00
77_P 102_E 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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