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OPENSEQ.org

NUOH - NUOJ
UniProt: P0AFD4 - P0AFE0
Length: 509
Sequences: 946
Seq/Len: 1.97
I_Prob: 0.99

NUOH - NADH-quinone oxidoreductase subunit H
Paralog alert: 0.24 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: HYCD HYFC NUOH
NUOJ - NADH-quinone oxidoreductase subunit J
Paralog alert: 0.06 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: NUOJ
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
4he8HC:JDContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
114_I 53_A 2.32 0.99
297_V 52_G 1.65 0.89
82_I 27_H 1.62 0.88
79_D 27_H 1.43 0.77
294_Y 70_V 1.40 0.75
314_L 20_I 1.32 0.69
39_L 141_V 1.26 0.62
235_G 158_V 1.15 0.51
115_G 130_G 1.14 0.49
162_L 46_L 1.11 0.47
158_V 43_F 1.11 0.47
128_Y 74_L 1.10 0.46
80_R 41_G 1.08 0.43
128_Y 70_V 1.06 0.41
133_A 29_L 1.06 0.40
294_Y 67_F 1.05 0.39
69_F 63_I 1.05 0.39
136_S 35_S 1.05 0.39
125_L 37_L 1.05 0.39
294_Y 25_P 1.04 0.39
39_L 13_I 1.04 0.38
125_L 24_N 1.03 0.38
61_V 14_L 1.02 0.36
219_Q 60_A 1.01 0.35
93_S 57_I 1.01 0.35
114_I 127_K 1.00 0.34
306_L 129_V 1.00 0.34
306_L 37_L 0.97 0.31
159_F 35_S 0.97 0.31
279_M 32_L 0.97 0.30
167_V 137_Y 0.97 0.30
132_F 51_A 0.96 0.30
294_Y 134_F 0.96 0.30
160_L 26_V 0.96 0.29
116_I 13_I 0.95 0.29
18_A 58_V 0.95 0.29
169_A 144_A 0.95 0.29
214_Q 28_A 0.95 0.28
128_Y 134_F 0.94 0.28
23_L 4_A 0.94 0.28
85_L 146_M 0.94 0.27
97_A 58_V 0.94 0.27
173_S 36_L 0.93 0.27
281_M 136_P 0.93 0.27
99_A 5_F 0.92 0.26
217_A 154_V 0.92 0.25
86_A 5_F 0.92 0.25
176_M 19_V 0.91 0.25
298_M 64_M 0.91 0.25
127_V 65_V 0.91 0.25
294_Y 74_L 0.91 0.25
90_A 17_L 0.90 0.24
128_Y 25_P 0.90 0.24
159_F 67_F 0.90 0.24
309_T 132_T 0.90 0.24
50_N 67_F 0.90 0.24
159_F 152_L 0.90 0.24
51_R 152_L 0.89 0.23
120_L 29_L 0.89 0.23
127_V 22_H 0.89 0.23
68_F 57_I 0.89 0.23
110_A 37_L 0.89 0.23
309_T 154_V 0.89 0.23
297_V 154_V 0.89 0.22
54_W 2_E 0.88 0.22
52_V 52_G 0.88 0.22
308_L 121_G 0.88 0.22
185_H 63_I 0.88 0.22
254_T 147_L 0.88 0.22
19_V 51_A 0.88 0.22
194_F 161_E 0.88 0.22
85_L 114_V 0.88 0.22
64_M 42_V 0.88 0.22
298_M 137_Y 0.87 0.21
305_C 19_V 0.87 0.21
21_I 129_V 0.87 0.21
25_V 56_I 0.87 0.21
164_L 15_A 0.87 0.21
251_L 26_V 0.87 0.21
201_I 134_F 0.87 0.21
305_C 101_A 0.86 0.21
121_M 151_G 0.86 0.20
122_M 37_L 0.86 0.20
158_V 133_L 0.86 0.20
300_F 105_V 0.86 0.20
127_V 64_M 0.85 0.20
319_V 135_G 0.85 0.20
135_W 67_F 0.85 0.19
188_N 18_R 0.85 0.19
120_L 142_E 0.85 0.19
113_N 82_E 0.84 0.19
140_K 149_L 0.84 0.19
210_H 71_V 0.84 0.19
128_Y 68_V 0.84 0.19
214_Q 154_V 0.84 0.18
314_L 9_G 0.83 0.18
205_A 149_L 0.83 0.18
83_F 23_T 0.83 0.18
201_I 109_Y 0.83 0.18
188_N 167_V 0.83 0.18
85_L 32_L 0.83 0.18
238_F 35_S 0.83 0.18
115_G 165_G 0.83 0.17
196_F 31_Y 0.82 0.17
158_V 57_I 0.82 0.17
223_D 129_V 0.82 0.17
168_V 19_V 0.82 0.17
251_L 63_I 0.82 0.17
217_A 155_A 0.82 0.17
171_A 33_I 0.82 0.17
292_P 68_V 0.82 0.17
246_V 56_I 0.82 0.17
87_P 61_G 0.81 0.17
125_L 33_I 0.81 0.17
98_F 36_L 0.81 0.17
31_F 84_E 0.81 0.16
285_I 130_G 0.81 0.16
78_S 127_K 0.81 0.16
311_I 10_L 0.81 0.16
108_V 16_T 0.81 0.16
277_F 10_L 0.81 0.16
84_T 146_M 0.81 0.16
188_N 106_V 0.80 0.16
276_A 139_L 0.80 0.16
182_S 147_L 0.80 0.16
253_V 16_T 0.80 0.16
95_L 126_A 0.80 0.16
151_A 29_L 0.80 0.16
296_Q 156_F 0.80 0.16
97_A 79_S 0.80 0.15
161_G 64_M 0.80 0.15
190_I 79_S 0.80 0.15
42_L 156_F 0.79 0.15
11_I 3_F 0.79 0.15
39_L 14_L 0.79 0.15
101_V 102_I 0.79 0.15
177_T 56_I 0.79 0.15
280_M 151_G 0.79 0.15
158_V 146_M 0.79 0.15
85_L 4_A 0.79 0.15
82_I 30_L 0.79 0.15
111_D 13_I 0.79 0.15
120_L 28_A 0.78 0.14
174_F 132_T 0.78 0.14
254_T 152_L 0.78 0.14
253_V 93_W 0.78 0.14
294_Y 64_M 0.78 0.14
289_L 15_A 0.78 0.14
136_S 43_F 0.78 0.14
197_I 90_P 0.78 0.14
203_G 146_M 0.78 0.14
197_I 80_E 0.78 0.14
120_L 18_R 0.78 0.14
149_A 94_I 0.77 0.14
161_G 70_V 0.77 0.14
174_F 126_A 0.77 0.14
128_Y 67_F 0.77 0.14
161_G 65_V 0.77 0.14
22_L 37_L 0.77 0.14
301_G 64_M 0.77 0.14
51_R 60_A 0.77 0.14
130_V 16_T 0.77 0.14
51_R 64_M 0.77 0.14
129_A 23_T 0.76 0.13
292_P 73_M 0.76 0.13
72_D 48_A 0.76 0.13
111_D 156_F 0.76 0.13
38_R 141_V 0.76 0.13
72_D 38_A 0.76 0.13
264_L 113_G 0.76 0.13
189_V 40_S 0.76 0.13
265_L 98_I 0.76 0.13
277_F 58_V 0.76 0.13
14_T 4_A 0.76 0.13
240_G 47_G 0.75 0.13
313_L 105_V 0.75 0.13
146_A 29_L 0.75 0.13
203_G 136_P 0.75 0.12
65_I 164_A 0.75 0.12
311_I 88_L 0.75 0.12
128_Y 62_A 0.75 0.12
265_L 3_F 0.75 0.12
139_N 63_I 0.74 0.12
317_A 54_L 0.74 0.12
161_G 158_V 0.74 0.12
165_M 146_M 0.74 0.12
153_T 64_M 0.74 0.12
78_S 126_A 0.74 0.12
247_T 98_I 0.74 0.12
94_L 16_T 0.74 0.12
129_A 68_V 0.74 0.12
228_E 133_L 0.74 0.12
215_P 145_S 0.74 0.12
273_L 94_I 0.74 0.12
141_Y 21_T 0.74 0.12
65_I 90_P 0.73 0.11
253_V 17_L 0.73 0.11
95_L 153_V 0.73 0.11
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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