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OPENSEQ.org

PUR3 - PUR9
UniProt: P08179 - P15639
Length: 741
Sequences: 460
Seq/Len: 0.65
I_Prob: 0.00

PUR3 - Phosphoribosylglycinamide formyltransferase
Paralog alert: 0.62 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: FMT PUR3
PUR9 - Bifunctional purine biosynthesis protein PurH
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PUR9
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
7_I 148_V 1.13 0.00
150_L 262_Y 1.05 0.00
92_L 77_G 1.04 0.00
181_I 343_I 1.03 0.00
81_D 354_K 1.02 0.00
51_I 57_Y 1.00 0.00
88_F 123_V 0.98 0.00
157_F 382_V 0.93 0.00
123_Q 448_M 0.92 0.00
168_R 87_D 0.90 0.00
189_L 519_M 0.90 0.00
165_I 81_G 0.89 0.00
186_D 75_V 0.89 0.00
73_H 151_S 0.89 0.00
20_A 437_N 0.88 0.00
2_N 141_H 0.87 0.00
51_I 87_D 0.85 0.00
51_I 364_V 0.84 0.00
94_P 154_D 0.84 0.00
136_V 123_V 0.83 0.00
10_N 519_M 0.83 0.00
91_I 123_V 0.83 0.00
2_N 193_Y 0.82 0.00
153_K 42_R 0.82 0.00
110_S 47_K 0.82 0.00
148_V 162_D 0.81 0.00
116_P 453_S 0.81 0.00
105_L 471_S 0.81 0.00
161_S 297_G 0.81 0.00
97_V 121_D 0.80 0.00
39_D 528_R 0.80 0.00
3_I 332_Q 0.79 0.00
130_E 162_D 0.79 0.00
128_G 403_V 0.79 0.00
6_L 256_Q 0.79 0.00
91_I 484_G 0.79 0.00
175_A 493_V 0.79 0.00
89_M 348_A 0.78 0.00
132_H 348_A 0.78 0.00
112_L 103_V 0.78 0.00
92_L 455_K 0.77 0.00
88_F 23_F 0.77 0.00
128_G 19_G 0.77 0.00
123_Q 445_A 0.77 0.00
33_V 481_F 0.77 0.00
92_L 482_R 0.77 0.00
71_L 434_Y 0.77 0.00
103_R 355_I 0.77 0.00
68_D 265_I 0.76 0.00
164_D 415_R 0.76 0.00
80_P 520_L 0.76 0.00
42_G 55_S 0.75 0.00
166_T 166_S 0.75 0.00
88_F 33_E 0.75 0.00
120_T 454_A 0.75 0.00
12_S 485_I 0.75 0.00
42_G 528_R 0.74 0.00
164_D 12_L 0.74 0.00
91_I 12_L 0.73 0.00
3_I 300_I 0.73 0.00
34_F 65_D 0.73 0.00
115_Y 19_G 0.73 0.00
184_F 306_R 0.73 0.00
124_A 456_I 0.73 0.00
100_Y 326_L 0.73 0.00
73_H 354_K 0.73 0.00
197_W 521_F 0.73 0.00
63_S 160_M 0.73 0.00
26_I 463_D 0.73 0.00
180_V 262_Y 0.73 0.00
154_V 378_D 0.72 0.00
110_S 304_Y 0.72 0.00
53_T 136_S 0.72 0.00
24_N 453_S 0.72 0.00
96_F 300_I 0.72 0.00
166_T 304_Y 0.72 0.00
52_A 29_A 0.71 0.00
92_L 93_H 0.71 0.00
134_T 65_D 0.71 0.00
12_S 513_D 0.71 0.00
2_N 354_K 0.71 0.00
114_K 172_R 0.71 0.00
148_V 408_Q 0.71 0.00
85_L 55_S 0.71 0.00
125_L 54_V 0.71 0.00
181_I 434_Y 0.71 0.00
185_A 439_M 0.71 0.00
61_F 306_R 0.70 0.00
17_I 357_A 0.70 0.00
50_G 174_D 0.70 0.00
149_I 521_F 0.70 0.00
130_E 170_A 0.70 0.00
42_G 25_Q 0.70 0.00
91_I 296_I 0.70 0.00
13_N 83_R 0.69 0.00
137_H 103_V 0.69 0.00
192_H 436_K 0.69 0.00
43_L 455_K 0.69 0.00
100_Y 226_M 0.69 0.00
192_H 364_V 0.69 0.00
30_V 43_L 0.69 0.00
39_D 299_S 0.69 0.00
166_T 98_I 0.69 0.00
118_L 481_F 0.69 0.00
12_S 404_V 0.69 0.00
42_G 266_A 0.69 0.00
161_S 355_I 0.69 0.00
170_Q 286_V 0.69 0.00
68_D 272_L 0.69 0.00
181_I 321_A 0.69 0.00
89_M 445_A 0.68 0.00
139_V 316_F 0.68 0.00
152_A 8_R 0.68 0.00
163_D 33_E 0.68 0.00
118_L 49_L 0.68 0.00
166_T 448_M 0.68 0.00
50_G 388_V 0.68 0.00
143_L 419_F 0.68 0.00
164_D 507_E 0.68 0.00
153_K 173_F 0.68 0.00
110_S 334_I 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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