| UniProt: | P08179 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10799 | ||
| Length: | 212 (200) | ||
| Sequences: | 4057 | ||
| Seq/Len: | 20.29 |
| PUR3
Paralog alert: 0.62 [within 20: 0.02] - ratio of genomes with paralogs Cluster includes: FMT PUR3 |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 131_E | 153_K | 3.259 | 1.00 | |
| 142_E | 145_G | 3.108 | 1.00 | |
| 7_I | 42_G | 2.819 | 1.00 | |
| 140_T | 145_G | 2.801 | 1.00 | |
| 160_D | 168_R | 2.632 | 1.00 | |
| 2_N | 29_T | 2.556 | 1.00 | |
| 4_V | 80_P | 2.482 | 1.00 | |
| 70_E | 73_H | 2.368 | 1.00 | |
| 94_P | 98_S | 2.309 | 1.00 | |
| 32_A | 78_Y | 2.258 | 1.00 | |
| 115_Y | 129_D | 2.248 | 1.00 | |
| 15_Q | 19_D | 2.23 | 1.00 | |
| 76_D | 99_H | 2.193 | 1.00 | |
| 138_F | 149_I | 2.175 | 1.00 | |
| 119_H | 122_R | 2.168 | 1.00 | |
| 114_K | 129_D | 2.157 | 1.00 | |
| 115_Y | 127_N | 2.149 | 1.00 | |
| 135_S | 148_V | 2.064 | 1.00 | |
| 94_P | 141_D | 2.025 | 1.00 | |
| 122_R | 126_E | 2.02 | 1.00 | |
| 150_L | 176_I | 1.966 | 1.00 | |
| 138_F | 184_F | 1.921 | 1.00 | |
| 152_A | 179_L | 1.907 | 1.00 | |
| 4_V | 32_A | 1.859 | 1.00 | |
| 122_R | 162_E | 1.847 | 1.00 | |
| 91_I | 143_L | 1.794 | 1.00 | |
| 82_V | 181_I | 1.782 | 1.00 | |
| 105_L | 149_I | 1.768 | 1.00 | |
| 160_D | 164_D | 1.746 | 1.00 | |
| 136_V | 180_V | 1.688 | 1.00 | |
| 63_S | 66_A | 1.665 | 1.00 | |
| 44_E | 47_R | 1.651 | 1.00 | |
| 14_L | 33_V | 1.644 | 1.00 | |
| 161_S | 164_D | 1.617 | 1.00 | |
| 17_I | 181_I | 1.61 | 1.00 | |
| 152_A | 175_A | 1.604 | 1.00 | |
| 73_H | 77_M | 1.595 | 1.00 | |
| 18_I | 49_A | 1.564 | 1.00 | |
| 150_L | 180_V | 1.564 | 1.00 | |
| 22_K | 49_A | 1.554 | 1.00 | |
| 157_F | 168_R | 1.55 | 1.00 | |
| 125_L | 165_I | 1.548 | 1.00 | |
| 98_S | 141_D | 1.545 | 1.00 | |
| 74_E | 77_M | 1.543 | 1.00 | |
| 97_V | 104_L | 1.515 | 1.00 | |
| 57_I | 60_A | 1.513 | 1.00 | |
| 2_N | 31_R | 1.496 | 1.00 | |
| 54_H | 74_E | 1.479 | 1.00 | |
| 152_A | 172_Q | 1.446 | 1.00 | |
| 15_Q | 45_R | 1.44 | 1.00 | |
| 45_R | 49_A | 1.44 | 1.00 | |
| 3_I | 28_G | 1.436 | 1.00 | |
| 182_S | 186_D | 1.433 | 1.00 | |
| 33_V | 46_A | 1.408 | 1.00 | |
| 120_T | 123_Q | 1.368 | 0.99 | |
| 123_Q | 126_E | 1.343 | 0.99 | |
| 121_H | 169_V | 1.334 | 0.99 | |
| 157_F | 160_D | 1.333 | 0.99 | |
| 154_V | 172_Q | 1.324 | 0.99 | |
| 44_E | 48_Q | 1.31 | 0.99 | |
| 72_I | 99_H | 1.299 | 0.99 | |
| 1_M | 187_G | 1.297 | 0.99 | |
| 52_A | 78_Y | 1.294 | 0.99 | |
| 56_L | 67_Y | 1.285 | 0.99 | |
| 16_A | 20_A | 1.27 | 0.99 | |
| 18_I | 51_I | 1.267 | 0.99 | |
| 4_V | 75_I | 1.251 | 0.99 | |
| 69_R | 95_A | 1.248 | 0.99 | |
| 41_F | 45_R | 1.24 | 0.98 | |
| 72_I | 100_Y | 1.236 | 0.98 | |
| 183_W | 188_R | 1.194 | 0.98 | |
| 38_A | 41_F | 1.186 | 0.98 | |
| 19_D | 45_R | 1.174 | 0.98 | |
| 2_N | 79_A | 1.174 | 0.98 | |
| 152_A | 176_I | 1.173 | 0.98 | |
| 150_L | 155_P | 1.159 | 0.97 | |
| 10_N | 170_Q | 1.151 | 0.97 | |
| 121_H | 124_A | 1.147 | 0.97 | |
| 179_L | 183_W | 1.146 | 0.97 | |
| 84_V | 181_I | 1.146 | 0.97 | |
| 162_E | 166_T | 1.145 | 0.97 | |
| 41_F | 47_R | 1.145 | 0.97 | |
| 5_V | 14_L | 1.136 | 0.97 | |
| 65_E | 95_A | 1.136 | 0.97 | |
| 69_R | 73_H | 1.125 | 0.97 | |
| 31_R | 80_P | 1.122 | 0.97 | |
| 184_F | 189_L | 1.115 | 0.96 | |
| 32_A | 80_P | 1.11 | 0.96 | |
| 28_G | 185_A | 1.091 | 0.96 | |
| 19_D | 49_A | 1.079 | 0.95 | |
| 43_L | 53_T | 1.06 | 0.95 | |
| 72_I | 76_D | 1.057 | 0.95 | |
| 41_F | 44_E | 1.056 | 0.95 | |
| 114_K | 131_E | 1.053 | 0.95 | |
| 150_L | 183_W | 1.043 | 0.94 | |
| 166_T | 170_Q | 1.033 | 0.94 | |
| 105_L | 177_Y | 1.026 | 0.94 | |
| 175_A | 179_L | 1.022 | 0.93 | |
| 124_A | 156_V | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1jkxA | 4 | 1 | 100 | 0.101 | Contact Map | 0.762 |
| 3av3A | 1 | 0.9858 | 100 | 0.121 | Contact Map | 0.778 |
| 3aufA | 1 | 0.9717 | 100 | 0.13 | Contact Map | 0.813 |
| 3tqrA | 1 | 0.9858 | 100 | 0.137 | Contact Map | 0.738 |
| 2ywrA | 1 | 0.9906 | 100 | 0.141 | Contact Map | 0.771 |
| 4ds3A | 1 | 0.9387 | 100 | 0.145 | Contact Map | 0.692 |
| 4ew1A | 1 | 0.9858 | 100 | 0.154 | Contact Map | 0.814 |
| 3nrbA | 4 | 0.9387 | 100 | 0.157 | Contact Map | 0.673 |
| 3p9xA | 2 | 0.9717 | 100 | 0.162 | Contact Map | 0.799 |
| 3obiA | 4 | 0.9387 | 100 | 0.163 | Contact Map | 0.697 |
Sequence Conservation (Image Generated using WebLogo v3)