May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [Q:0171] and [E:0173]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.1 -0.1 -0.1 0.5 0 0 -0.4 0.6 -0.2 -0.5 -0.2 0.1 -0.3 0.4 0.4 -0.2 0.6 -0.2 0.1
F 0.4 -0.1 -0.3 -0.1 -0.3 0.1 0 0.1 -0.1 0 0 -0.3 0.2 0.3 -0.5 0.5 0.8 -0.4 0 0.1
I 0.1 -0.1 -0.1 0.2 0.2 0 0 -0.4 0.5 0.7 -0.1 -0.2 -0.2 -0.3 -0.3 0.2 -0.2 0.2 -0.1 -0.1
L 0.4 -0.1 -0.1 -0.1 0.4 0 0 -0.4 0 0.5 -0.2 -0.3 -0.3 0 0.1 1 -0.3 -0.6 -0.5 -0.2
V 0.6 -0.1 -0.1 -0.2 -0.2 -0.1 0 -0.4 0.3 0.3 0 -0.3 0.1 -0.3 0.6 -0.2 0.1 0.7 0 -0.1
M -0.2 0 -0.1 -0.1 -0.1 0 0 -0.2 -0.1 0.7 -0.3 -0.1 0.2 -0.1 -0.1 0.5 -0.1 0.4 -0.3 -0.1
W -0.1 0 0 0 0 0 0 0 -0.2 -0.3 -0.1 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 0.8 0
Y 0.5 -0.1 0 -0.2 -0.2 -0.1 0 -0.2 0 -0.5 0.1 0.1 -0.1 0.4 -0.1 0.6 1 -0.6 0.3 0
D -0.5 -0.1 -0.2 0.3 0.2 -0.1 0 -0.5 0.3 -0.5 1.6 0.2 -0.3 0.5 -0.2 -0.4 0.3 -0.2 -0.1 -0.2
E -0.3 -0.1 0.3 0.3 0.2 0 0 0.7 -0.5 0 0.1 0.2 0.1 0.1 -0.2 -0.3 0.1 0.2 -0.5 -0.1
K -0.3 0.1 -0.1 -0.1 -0.2 0.4 0 0.5 0.3 0.5 0.2 -0.3 -0.3 0 -0.3 0.4 0 0.1 -0.6 -0.2
R 0.3 -0.1 0.5 -0.1 0.6 -0.1 0 -0.1 -0.6 0.3 -0.4 -0.1 -0.1 -0.1 0.1 0.3 -0.1 0.4 0 0.1
H 0.6 -0.2 0 0.2 0 -0.1 -0.1 -0.1 0.4 -0.4 0.6 0.5 -0.2 0.1 0.1 -0.5 -0.5 0 -0.1 -0.1
N -0.1 0 -0.1 -0.1 -0.1 0 0 0.1 0.3 -0.1 0.3 0.2 -0.2 0.6 -0.2 -0.4 0 0 -0.3 -0.1
Q -0.6 0.6 -0.2 -0.3 -0.4 -0.1 0 1.7 0.1 0.4 -0.6 0 -0.1 -0.2 0.1 0 0.1 -0.5 -0.8 0.9
S -0.2 -0.1 -0.2 0.2 0.1 -0.1 0 0.2 0 0.3 -0.3 -0.1 0 0.3 0 -0.3 -0.1 0.4 0.8 -0.2
T -0.3 -0.1 -0.1 -0.1 -0.2 0 0 0.1 0 0.5 -0.4 -0.2 0.1 0.1 0.1 -0.2 -0.2 -0.5 0.8 0.3
G -0.7 -0.2 1.1 0.5 0.2 -0.1 -0.1 -0.5 0.2 -0.9 0.3 0.7 0.7 -0.4 0.5 -0.7 -0.2 -0.2 0.5 -0.2
P 0.3 0 0 0 0 0 0 -0.1 -0.2 0.3 -0.1 0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0
C -0.1 0 0 0 0 0 0 0 -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.3 0 -0.1 0.2 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0171 -0.2 0.6 0.4 0.3 0.4 -0.6 -1.2 0.7 0.3 -0.1 -0.3 0.3 0.5 -0.6 0.3 0.2 -0.2 0.4 -1.1 -1.3
0173 0 -0.8 -0.4 -0.5 0.1 -0.9 -1.2 -0.6 1.3 1.9 0.6 -0.2 -0.5 0.3 0.2 0.6 0.1 0.4 -0.2 -0.4
Select residue pair below:
i_j Score Prob
0029_0173 1.012 0.90
0173_0176 0.531 0.29
0030_0173 0.507 0.26
Local Interactions:
i_j Score Prob
0173_0174 0.678 0.51
0173_0175 0.654 0.47
0171_0173 0.522 0.27
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0166 seconds.