May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [M:0140] and [K:0177]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.4 0.2 -0.1 0.2 0.1 -0.1 -0.1 -0.1 -0.1 0.1 -0.7 0.1 0.7 -0.2 -0.6 -0.2 0.9 -0.5 0.3 -0.2
F 0 -0.1 -0.1 0 -0.1 0 -0.1 0 -0.3 0.5 -0.4 -0.2 -0.1 -0.2 0.1 0.3 0 -0.1 0.3 -0.1
I 0.2 0 0 0 0.4 0 0 0 -0.2 -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.3 0
L -0.6 0.5 -0.1 -0.1 -0.2 0.6 1 -0.1 -0.5 -0.1 -0.5 -0.1 -0.2 -0.1 1.1 0 -0.3 -0.4 0.2 0.1
V 0.7 0 0 0 0 0 0 0 -0.1 0.1 0.2 -0.3 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 0
M 0.2 0 0 0 -0.1 0 0 0 0 -0.4 0.1 0.1 -0.1 -0.1 0.2 0.2 0.5 -0.1 -0.3 0
W -0.1 0 0 0 0 0 0 0 -0.1 0.1 -0.1 0.2 0 -0.1 -0.1 -0.2 -0.1 -0.1 0.5 0
Y -0.6 0.3 -0.1 -0.1 -0.1 -0.1 -0.1 0.7 0 0.2 0.2 -0.6 -0.3 0.6 -0.3 0.1 -0.1 -0.4 0.1 0.2
D 0.4 -0.2 0.2 0 0.4 -0.4 -0.3 -0.3 0.4 -0.2 0.2 0.6 -0.1 0.1 -0.8 0.2 -0.2 0.5 0.5 0.8
E -0.1 -0.2 0.1 0.3 -0.3 -0.1 -0.2 -0.1 0 -0.4 0.8 1 -0.5 0 -0.1 -0.5 -0.1 0.9 0.2 -0.1
K -0.3 0.1 -0.2 -0.2 -0.3 -0.1 -0.2 -0.1 0.6 0.9 0.2 -0.4 0.4 -0.4 1.3 -0.1 -0.6 0.1 -0.2 -0.2
R 0.2 -0.1 -0.1 -0.1 -0.1 0 -0.1 -0.1 -0.3 0.4 0.8 -0.5 1 -0.3 0.3 -0.5 -0.1 0.6 -0.5 -0.1
H 0.7 0.3 0.2 -0.3 -0.3 0 -0.2 -0.3 0.9 -0.1 -0.3 -0.1 0.3 0 -0.2 0.5 -0.4 0.3 0.1 -0.4
N -0.4 -0.3 0.1 0.5 0.7 -0.1 0 -0.1 -0.2 0.3 -0.3 -0.6 -0.4 0.1 0.2 0.6 0.7 -0.2 0.1 -0.2
Q 0.9 -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.6 -0.5 0.5 0.4 -0.3 0.6 0.3 -0.5 -0.3 -0.3 -0.2 0.2
S -0.2 -0.1 0.3 -0.1 0.3 0 0.1 0 0.1 -0.3 -0.2 -0.1 0.5 -0.3 -0.3 0.4 0.5 0.6 -0.6 -0.1
T -0.1 -0.1 -0.1 -0.1 -0.1 0 -0.1 0.1 0 0.2 0.2 0.2 -0.1 0.2 0 0.3 0.2 -0.2 -0.5 -0.1
G -0.2 -0.1 -0.1 0.3 -0.1 0 -0.1 0 -0.4 -0.1 0.7 0.3 -0.2 0.2 -0.1 0.1 -0.6 0 0.7 -0.1
P -0.2 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0.6 0 -0.6 0.5 -0.3 0.3 -0.2 -0.4 0.7 -0.1 -0.5 0.1
C -0.1 0 0 0 0 0 0 0 -0.1 -0.2 0.3 -0.2 -0.1 -0.1 -0.1 -0.1 0.2 -0.1 0.2 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0140 0.4 -0.5 -1 0.4 -1 -0.7 -1.1 0 1.9 0.9 0.7 0.1 0.7 0.9 0.3 0 -0.2 0 0.1 -1.2
0177 0.8 -0.8 -0.7 -0.7 -0.6 -1.4 -1.1 -1.3 0.8 1.3 1 0.7 -0.1 0.3 0.5 0.6 0.8 0.3 0.7 -0.9
Select residue pair below:
i_j Score Prob
0013_0140 3.203 1.00
0140_0179 1.121 0.95
0140_0177 0.874 0.79
Local Interactions:
i_j Score Prob
0140_0141 0.914 0.83
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0131 seconds.